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Children's Medical Research Institute @cmri.bsky.social · 10d

2/2 This new research brings us a step closer to more personalised care and improving survival for people affected by this very challenging type of cancer.

You can read the full publication here: aacrjournals.org/cancerrescom...

Mapping the Proteomic Landscape of Pancreatic Cancer: Prognostic Insights and Subtype Stratification

Abstract. Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy that lacks reliable biomarkers to guide treatment decisions. Effective prognostic tools are needed to improve its clinical ...

aacrjournals.org

Children's Medical Research Institute @cmri.bsky.social · 10d

1/2 In work published this weekend, Children's Medical Research Institute's ProCan® team and collaborating cancer researchers have uncovered new clues in the proteins of pancreatic cancer that could help clinicians detect the disease earlier and choose the best treatments for each patient.

Scientist working on lab equipment while colleagues converse in a high-tech research lab.

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Children's Medical Research Institute @cmri.bsky.social · 23d

We work with closely with the team at SCHN, particularly in the exciting field of gene and cell therapies, and it was wonderful to hear Michelle passionately explain how scientists and clinicians can work together to bring treatments to children sooner.

A lecture or presentation in a room with wooden walls and ceiling. Attendees are seated in rows facing a screen displaying a presentation slide. One person stands at the podium presenting, while another stands to the side. The room is well-lit with overhead lights.

Children's Medical Research Institute @cmri.bsky.social · 23d

We are incredibly grateful to Dr Michelle Lorentzos, Advanced Therapeutics Medical Lead at The Sydney Children’s Hospital Network, for taking the time to speak at Children's Medical Research Institute last Friday.

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Children's Medical Research Institute @cmri.bsky.social · 28d

Please take the time to ask, listen, and check in with the people around you. Because life happens every day.

Children's Medical Research Institute @cmri.bsky.social · 28d

Supporting wellbeing is central to how we work together, because without our people we could not carry out our vital research for children’s health.

A big thank you to our People Team for organising such a thoughtful event for staff.

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Children's Medical Research Institute @cmri.bsky.social · 28d

Today at Children’s Medical Research Institute, staff gathered to mark R U OK? Day.

R U OK? Day reminds us of the importance of looking out for one another and taking time to connect. At CMRI, every employee matters.

Six people standing together in a room with wooden ceiling panels and overhead lighting, all wearing yellow clothing or accessories and holding yellow items like mugs or cups. Two screens are visible in the background.

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Children's Medical Research Institute @cmri.bsky.social · Jul 25

Congratulations to Dr Pragathi Masamsetti and our Embryology team for receiving front page of Developmental Cell @cellpress.bsky.social this week. The knowledge gained through this publication enriches our understanding of early human development. Read more here: doi.org/10.1016/j.de...

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Children's Medical Research Institute @cmri.bsky.social · Jul 17

We’re proud of our researcher Dr Radek Szmyd who has received a 2025 University of Sydney Faculty of Medicine and Health Mid-Career Research Outstanding Publication Award - for Radek’s extraordinary work to understand why cancer cells die in different ways following radiotherapy.

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Children's Medical Research Institute @cmri.bsky.social · Jul 11

Congratulations to A/Prof Pengyi Yang, Head of CMRI’s Computational Systems Biology Unit, on receiving Australian Research Council 2025's Future Fellowship! His project will use single-cell omics technologies to improve the study of cell programming.

Read more here: www.arc.gov.au/news-publica...

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Children's Medical Research Institute @cmri.bsky.social · Jul 2

We are excited to announce a groundbreaking study out in @natcomms.nature.com from #CMRI Dr Alex Sobinoff & team. They have discovered proteins that guide telomerase — opening doors to new treatments for #cancer, aging & genetic disease. Read more: www.cmrijeansforgenes.org.au/news/scienti...

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Reposted by Children's Medical Research Institute

Dr Kate Giles @scientistkate.bsky.social · Jun 8

There is still lots of time to donate. every $$ counts and contributes to the essential medical research being done at @cmri.bsky.social

city2surf25.grassrootz.com/cmri/kate-g

Kate G in 2025 Voltaren City2Surf

Hi Friends! I am a Postdoc Researcher at CMRI and this year I'm participating in C2S to raise funds for the research we do here. I am trying to fundraise $5000 and would be so grateful for any donati...

city2surf25.grassrootz.com

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Children's Medical Research Institute @cmri.bsky.social · Apr 17

Touring CMRI labs and meeting with our scientists, the Governor-General took tremendous interest in our research. We were delighted to hear that Her Excellency had been participating in Jeans for Genes Day since its inception and will wear her DNA double helix pin with pride.

A person in PPE gear looking through a microscope.

Three people in PPE gear taking a selfie in a lab and one of them putting up the peace sign.

Four people in a lab having a nice discussion together.

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Children's Medical Research Institute @cmri.bsky.social · Apr 17

Children's Medical Research Institute is thrilled to announce Her Excellency the Honourable Ms Sam Mostyn AC, Australia’s Governor-General, as our Patron. We were delighted to welcome Her Excellency to the institute today.

A person in brown professional attire standing proudly behind a CMRI podium stand.

A room full of people proudly standing together.

A group of five people in PPE gear in a lab.

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Children's Medical Research Institute @cmri.bsky.social · Apr 16

A new research group at CMRI, led by Dr Rebecca Poulos, aims to improve precision medicine for hard-to-treat #childhoodcancers. The Multi-Omics in Childhood Cancer group addresses urgent needs in diagnosis and treatment.
www.cmrijeansforgenes.org.au/news/newest-...

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Children's Medical Research Institute @cmri.bsky.social · Apr 11

CMRI is excited to announce that Dr Scott Cohen and Prof Tracy Bryan have won a $440,000 grant from @CCNewSouthWales for their work identifying two new drugs, known as telomerase inhibitors, that could work with chemotherapy to improve cancer treatment. www.cancercouncil.com.au/research-pt/...

Two people smiling proudly together in a lab.

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Children's Medical Research Institute @cmri.bsky.social · Mar 27

The NSW Organoid Innovation Centre was launched this week by NSW Chief Scientist Prof Hugh Durrant-Whyte with partners @sydney.edu.au and @unsw.bsky.social. A very exciting time for #stemcell research with CMRI at the forefront of this work. Read more: www.cmrijeansforgenes.org.au/news/organoi...

A group of seven people in a lab proudly smiling in their business attire.

Two people proudly standing in front of a CMRI/Jeans for Genes promotional pull up banner.

Children's Medical Research Institute @cmri.bsky.social · Mar 25

Congrats to Pragathi Masamsetti and our Embryology team on their @Dev_Cell publication! Their study is the first to reveal how the embryo forms its head which is key to understanding the cause of craniofacial malformations. Read more: www.cell.com/developmenta...

Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo

Masamsetti et al. identified a transient non-renewing cell population that displays dual lineage propensity for mesoderm and endoderm in mouse embryos at mid- to late-gastrulation. These mesendoderm p...

www.cell.com

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Children's Medical Research Institute @cmri.bsky.social · Mar 23

Congrats to Prof Patrick Tam on receiving the 2025 @isscr.org Public Service Award! As a member of their working group, he has played a key role in refining guidelines for Stem Cell Research and Clinical Translation. We're proud to see Patrick's contributions recognised globally.

2025 ISSCR Public Service Award Honoree - Patrick P.L. Tam, PhD, Children's Medical Research Institute, Australia.

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Children's Medical Research Institute @cmri.bsky.social · Mar 17

@thecesarelab.bsky.social at CMRI & Kyoto University have discovered the previously unknown “active’’ role that telomeres can play in avoiding #cancer. Now in Nature Communications @springernature.com: www.nature.com/articles/s41...

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Children's Medical Research Institute @cmri.bsky.social · Mar 13

This is going to be a great discussion. We can't wait! 🙌

Reposted by Children's Medical Research Institute

Tony Cesare @thecesarelab.bsky.social · Mar 4

Review from our lab out today: "Roles for the 3D Genome In the cell cycle, DNA replication, and double strand break repair." Written by @scientistkate.bsky.social, with her co-supervisor @piptaberlay.bsky.social and collaborator Mat Jones. www.frontiersin.org/journals/cel...

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Children's Medical Research Institute @cmri.bsky.social · Mar 3

We’ve had another amazing discovery from our ProCan® team – this time impacting #throatcancer! This collaborative project has led to a way for scientists to predict patients who may experience a recurrence of a type of throat cancer. Read more here: doi.org/10.1158/2767...

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Children's Medical Research Institute @cmri.bsky.social · Feb 19

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This initiative aims to serve the research community in NSW and across Australia, and everyone interested is invited to connect.

Join the network and share your views by registering your interest today: www.medicalresearch.nsw.gov.au/nat-net/

Non-Animal Technologies Network (NAT-Net) - NSW Health & Medical Research

www.medicalresearch.nsw.gov.au

Children's Medical Research Institute @cmri.bsky.social · Feb 19

Are you working in the non-animal technologies space?
The Non-Animal Technologies Network (NAT-Net), including CMRI, aims to make groundbreaking discoveries in the field of medicine and health while developing and promoting alternative methods that reduce the need to use animals in research. 1/

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