callista yee
@csybio.bsky.social
380 followers 300 following 220 posts
worm neurobiologist, assistant professor at UBC zoology. loves tater tots, synapses, dpy worms, and transcription factors. she/her. 🏳️‍🌈🇨🇦 Looking for grad students and postdocs!
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csybio.bsky.social
I will be opening my new lab in September at UBC! if you’re coming to #Worm25 and are looking for graduate studies or a postdoc position, let’s meet! Vancouver + worms = perfect vibes. www.zoology.ubc.ca/~yeecs/labsi... Please share! 🙌
csybio.bsky.social
I think he would love to hear from you - shoot him an email at lastname @ zoology dot ubc dot ca 🥰
csybio.bsky.social
got to hangout with don today and look what he gifted us…an original print of genetics that had The genetics of Caenorhabditis elegans by Brenner 😭 #celegans 🧪
copy of Genetics, Volume 77 number 1 Brenner’s The Generics of Caenorhabditis elegans in print format
Reposted by callista yee
celjauebel.bsky.social
Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :)
www.youtube.com/@Workingwith...
Working with C. elegans
This channel provides clear demonstrations of core C. elegans lab skills, including: recognizing life stages and common phenotypes, picking and manipulating worms, and maintaining healthy cultures. De...
www.youtube.com
Reposted by callista yee
johntngo.bsky.social
🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
csybio.bsky.social
this will not help my push to declutter the DECADES of random tchotchkes and trinkets that were left behind 🥲
csybio.bsky.social
1993 gilson pipettes!!! 😭😭😭😭
csybio.bsky.social
done, I will set aside one for you 🥰
csybio.bsky.social
I was pretty sure I never used this one then I looked it up and it was
unc-122p::gfp and now I feel dumb
csybio.bsky.social
also got a billion of cryo boxes but I haven’t figured out the best course yet with them… but they’re definitely $$$$$
csybio.bsky.social
I am ready for the apocalypse, got my sequence of pPD95.75 and others right here #celegans
floppy disk of fire lab vector sequences
csybio.bsky.social
living the car-free life unfortunately 😓
csybio.bsky.social
I am doing such a bad job at throwing things away. like look at these notes???

“We have some males produced by heat shock and they seem to be OK but not too enthusiastic”
csybio.bsky.social
if anyone wants a billion cardboard freezer boxes, hmu.
csybio.bsky.social
today in I’m Not Crying, You’re Crying, original reprints from the CGC (1976, 1977) #celegans
original reprints of two papers, from the CGC (stamped). 1976 and 1977.
csybio.bsky.social
heck yeah, soaking in all the good vibes
csybio.bsky.social
thank you so much 🥰
csybio.bsky.social
yeah honestly this is living the dream. so blessed.
csybio.bsky.social
got the keys to my office today - I’m not crying you’re crying
letter from nobel laureates in support of the C. elegans gene knockout facility at UBC
Reposted by callista yee
biorxiv-molbio.bsky.social
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1
Reposted by callista yee
ambystoma22.bsky.social
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
H3K4me3 amplifies transcription at intergenic active regulatory elements
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
csybio.bsky.social
heck yeah ethan!
dev-journal.bsky.social
Pathway to Independence – an interview with Chee Kiang (Ethan) Ewe.

In this interview, @ethanewe.bsky.social talks about about what drives and excites him, and what he hopes to achieve in his own lab:

journals.biologists.com/dev/article/...
Reposted by callista yee
barrlab.bsky.social
Worms love flies! Please consider donating to FlyBase. Model organisms unite! #celegans
flybase.bsky.social
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
FlyBase:Contribute to FlyBase - FlyBase Wiki
wiki.flybase.org