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Decision, Action, and Neural Computation (DANC) lab

@danclab.bsky.social

1.3K followers 2.8K following 110 posts

sensorimotor computations, beta bursts, laminar MEG, infant development 🧠🦾💥🍰👶 PI: James Bonaiuto www.danclab.com

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jun 2

It's been a while since our last laminar MEG paper, but we're back! This time we push beyond deep versus superficial distinctions and go whole hog. Check it out- lots more exciting stuff to come! 🧠📈

Maciek Szul @maciekszul.bsky.social · Jun 2

🚨🚨🚨PREPRINT ALERT🚨🚨🚨
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!

Overview of the simulation strategy and analysis. a) Pial and white matter boundaries
surfaces are extracted from anatomical MRI volumes. b) Intermediate equidistant surfaces are
generated between the pial and white matter surfaces (labeled as superficial (S) and deep (D)
respectively). c) Surfaces are downsampled together, maintaining vertex correspondence across
layers. Dipole orientations are constrained using vectors linking corresponding vertices (link vectors).
d) The thickness of cortical laminae varies across the cortical depth (70–72), which is evenly sampled
by the equidistant source surface layers. e) Each colored line represents the model evidence (relative
to the worst model, ΔF) over source layer models, for a signal simulated at a particular layer (the
simulated layer is indicated by the line color). The source layer model with the maximal ΔF is
indicated by “˄”. f) Result matrix summarizing ΔF across simulated source locations, with peak
relative model evidence marked with “˄”. g) Error is calculated from the result matrix as the absolute
distance in mm or layers from the simulated source (*) to the peak ΔF (˄). h) Bias is calculated as the
relative position of a peak ΔF(˄) to a simulated source (*) in layers or mm.

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 8d

It's just a way to split bursts into groups based on their waveform similarity along that PCA dimension. It's not the best way, and there may not be discrete groups - more of a continuum, but it useful. We're always looking for better ways to do it.

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 8d

Good point, but in this case it wouldn't be so informative because we lack temporal dynamics in this task. Beta power is lower than baseline when performing actions. The cool stuff is in the waveform-specific burst rates

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 9d

I'm co-organising a #CNS2026 symposium with @adykstra.bsky.social - "Non-invasive meso-scale dynamics of perception and cognition", including @darcywaller.bsky.social and @lonikefaes.bsky.social. If you're a member, please vote for it and help us make this happen!

Darcy Waller @darcywaller.bsky.social · 9d

If you’re a @cogneuronews.bsky.social member, check out and vote on the great lineup of symposia for 2026, and plz consider our symposium “Non-invasive meso-scale dynamics of perception and cognition”, organized by @adykstra.bsky.social including James Bonauito and @lonikefaes.bsky.social!

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Andrew (Andy) Dykstra @adykstra.bsky.social · 9d

What Darcy said! If you're a @cogneuronews.bsky.social member and want to learn at #CNS2026 how MEG and fMRI can yield circuit-level insight into perception and cognition, vote for our symposium! Co-organized by laminar MEG guru @danclab.bsky.social. Vote here! www.cogneurosociety.org/account-login/

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Darcy Waller @darcywaller.bsky.social · 9d

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 11d

Dude I got an anarchy symbol tattoo on my arm like 2 years ago to match the equality symbol on my other arm that I did stick-and-poke style when I was 16. Stop trying to age gracefully

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Reposted by Decision, Action, and Neural Computation (DANC) lab

Alina Studenova @studenova.bsky.social · 12d

Simulations are fun! Especially with the right tools😉.
@willenjoy.bsky.social and I (with support from Mina Jamshidi) made a toolbox for simulating EEG/MEG data
meegsim.readthedocs.io
I put together a quick simulation using it for this short clip. Took me 10 minutes (no, really!)
#brainmovies

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 15d

Congrats!

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 16d

Sf-what?

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 17d

This was a fun paper to work on! Thanks to Andy for coordinating this. It made me think more deeply about where we might be able to go with laminar MEG, and I learned a lot in the process! #neuroskyence

Andrew (Andy) Dykstra @adykstra.bsky.social · 18d

Our open-access article - Testing circuit-level theories of consciousness in humans - together with Yunkai Zhu, Carolina Fernandez Pujol, @dvwz.bsky.social, @jonescompneurolab.bsky.social, @tmarvan.bsky.social, and @danclab.bsky.social, was just published @cp-trendscognsci.bsky.social.

Trends in Cognitive Sciences @cp-trendscognsci.bsky.social · 18d

Online Now: Testing circuit-level theories of consciousness in humans

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 21d

🚨Postdoc job offer🚨
Are you interested in beta bursts? Want to help drive methods for laminar inference with MEG? Now hiring a postdoc: run head-cast MEG experiments, help build our laMEG toolbox, and collaborate across Lyon–Marseille–Strasbourg. emploi.cnrs.fr/Offres/CDD/U...
Please repost! 🧠📈

Portail Emploi CNRS - Offre d'emploi - Post-doctorate - Beta bursts & laminar MEG (M/F)

emploi.cnrs.fr

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Reposted by Decision, Action, and Neural Computation (DANC) lab

Ole Jensen @olejensen.bsky.social · 23d

In an EEG study spearheaded by Marlena Baldauf, we show that 8-month-old babies’ visual systems resonate at 4Hz (theta rhythm) — unlike adults, who resonate around 10Hz (alpha).

👶🧠 echoes at 4Hz
👩‍🦰🧠 echoes at ~10Hz

Preprint:
www.biorxiv.org/content/10.1...

Infant Brains Tick at 4Hz - Resonance Properties of the Developing Visual System

Neural rhythms of the infant brain are not well understood. Testing the rhythmic properties of the adult visual system with periodic or broadband visual stimulation elicited neural resonance phenomena...

www.biorxiv.org

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Ladislas Nalborczyk @lnalborczyk.bsky.social · Sep 1

Happy to share a new preprint in which @paulbuerkner.com and I introduce a novel model-based approach for precisely estimating the onset and offset of M/EEG effects!

www.biorxiv.org/content/10.1...

Precise temporal localisation of M/EEG effects with Bayesian generalised additive multilevel models

Time-resolved electrophysiological measurements such as those obtained through magneto- and electroencephalography (M/EEG) offer a unique window onto the neural activity underlying cognitive processes...

www.biorxiv.org

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Sep 3

youtu.be/XOLak7xRYGA?...

Zoidberg - LinkedIn

YouTube video by Alex '350'

youtu.be

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Aug 14

I had to bring my dog to a retreat talk once, and she barked at someone who came in late. It was hilarious. I don't have kids myself, but I say bring them!

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Jul 15

Beta burst waveform extraction using novel 4He-OPMs https://www.biorxiv.org/content/10.1101/2025.07.10.663870v1

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jul 23

Beta burst waveforms in PD! We find that specific types of beta bursts are rate-modulated by l-dopa, and STN-cortical connectivity during these burst types is related to clinical improvement. Fantastic work by Hasnae Agouram with @pierpasorre.bsky.social 🧠📈

Maciek Szul @maciekszul.bsky.social · Jul 16

🚨
Levodopa increased burst waveform-specific connectivity between STN and the sensorimotor cortex, which correlated with medication related improvement.

Beta burst waveforms look like a promising biomarker candidate for both disease severity and treatment response.

www.medrxiv.org/content/10.1...

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👻 George oOoOoOo’Neill 👻 @goneill.bsky.social · Jul 22

Pleased to see this paper finally published. We investigated which conductive models are appropriate for source analysis of spine electrophysiology. Turns out modelling the bone is quite important! www.nature.com/articles/s41...

Volume conductor models for magnetospinography - Scientific Reports

Scientific Reports - Volume conductor models for magnetospinography

www.nature.com

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jul 17

Check out Jan's poster if you're at @meguki2025.bsky.social Great work! I'm so pleased to see these results replicated independently, even with a different type of MEG scanner!

Jan Schalla @jan-sch.bsky.social · Jul 17

Just arrived at @meguki2025.bsky.social excited to present results on head movement reduction in people with Parkinson‘s using individual head casts. Additionally we can replicate prior findings on laminar source reconstruction! If you want to find out more, do not hesitate to find me at poster 45!

Poster 45 of MEGUKI 2025 from Jan Schalla.

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Thomas Pirenne @pirtho.bsky.social · Jul 17

I’m sure you’ve always wondered how reliable Granger causality of source reconstructed MEG really is. Better yet, you surely wonder how to improve it. You’re in luck, I’ve just arrived at @meguki2025.bsky.social to discuss it. All jokes aside, meet me at poster 38 if you’re interested. 👋🏼🧠

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jul 9

Paul, I did not know that you were such a monster

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jul 9

Now to introduce another student to emacs and pit them against each other

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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jun 29

When I was a kid we called it the stingray shuffle

Reposted by Decision, Action, and Neural Computation (DANC) lab

Natalie Schaworonkow @nschawor.bsky.social · Jun 23

happy that our article about mu & alpha rhythm waveform shape in development is now finally out in the open: doi.org/10.1162/jocn...

oscillation frequency changes across development (one of the most robust findings in the oscillation world). in this work, we also look at waveform shape changes.

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Peter Zeidman @corticalpete.bsky.social · Jun 23

And huge thanks to James Bonaiuto of @danclab.bsky.social - their fantastic laminar MEG toolbox laMEG paved the way to SPM-Python! github.com/danclab/laMEG

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jun 23

So cool to see this taking off! Soon laMEG won't have to support our own compiled version of SPM

Department of Imaging Neuroscience @imagingneuroucl.bsky.social · Jun 23

Drumroll... The SPM team will announce that SPM is now fully accessible from Python! 🐍 Learn more about SPM-Python at the SPM roundtable event (Friday, 1pm) and poster number 1841 at #OHBM2025. Try the beta for yourself at github.com/spm/spm-python [2/7]

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