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deeganlab.bsky.social
Deegan Lab
@deeganlab.bsky.social
170 followers 150 following 7 posts
Research group at MRC Human Genetics Unit in Edinburgh working on DNA replication (https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/deegan-group)
institute-genetics-cancer.ed.ac.uk
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · May 12
Application deadline is this Friday!
deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Apr 15
Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @mdc-berlin.bsky.social and @uoe-igc.bsky.social. See below for more details and please get in touch if you're interested.

www.findaphd.com/phds/project...
Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh on FindAPhD.com
PhD Project - Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Apr 15
Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @mdc-berlin.bsky.social and @uoe-igc.bsky.social. See below for more details and please get in touch if you're interested.

www.findaphd.com/phds/project...
Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh on FindAPhD.com
PhD Project - Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Apr 15
3rd edition of the fantastic UK DNA replication meeting is happening next September in Edinburgh. Don't miss out 🧬🏴󠁧󠁢󠁳󠁣󠁴󠁿

www.biochemistry.org/events-and-t...
UK DNA Replication Meeting 2026
Research in the DNA replication field is progressing at a remarkable rate. Technological innovations in biochemical reconstitution, structural biology, proteomics and DNA sequencing are helping to rap...
www.biochemistry.org
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Apr 14
Two weeks left to apply for this PhD opportunity in our group. Informal enquiries welcome.
deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Feb 7
4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection!

institute-genetics-cancer.ed.ac.uk/igc-graduate...
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Reposted by Deegan Lab
groth-anja.bsky.social
Anja Groth @groth-anja.bsky.social · Feb 26
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
 
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).

www.embl.org/about/info/c...
DNA replication and genome maintenance: from basic biology to disease
www.embl.org
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Feb 7
4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection!

institute-genetics-cancer.ed.ac.uk/igc-graduate...
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Jan 21
Congratulations Francesca. And looking forward to your seminar in Edinburgh later this week!
hubrechtinstitute.bsky.social
Hubrecht Institute @hubrechtinstitute.bsky.social · Jan 20
What if science truly is like volleyball, where teamwork and support are everything? We spoke with @fmattiroli.bsky.social, who recently earned tenure, to explore this question and more. Read her inspiring story here 👇 www.hubrecht.eu/francesca-ma...
Francesca Mattiroli got tenure: ‘Science is a team sport’ - Hubrecht Institute
She always dreamed of becoming a scientist. Francesca Mattiroli, has passed tenure evaluation with flying colors. She will expand her chromatin research.
www.hubrecht.eu
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Reposted by Deegan Lab
duxinlab.bsky.social
Duxin lab @duxinlab.bsky.social · Jan 16
A huge thanks to Ryo Fujisawa for joining our JC this week!

Ryo's formidable work on TTF2 from his recent article "TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε" was enlightening. Great scientific discussion!

Ryo's work doi.org/10.1101/2024...
TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε
Mammalian cells frequently enter mitosis before DNA replication has finished, necessitating the rapid processing of replication forks to facilitate chromosome segregation. The TRAIP ubiquitin ligase i...
doi.org
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Reposted by Deegan Lab
karimaj.bsky.social
Karim Majzoub @karimaj.bsky.social · Jan 15
Anti-venom spat out of a computer ! Thank you David Baker !
De novo designed proteins neutralize lethal snake venom toxins - Nature
Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...
www.nature.com
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deeganlab.bsky.social
Deegan Lab @deeganlab.bsky.social · Jan 6
Beautiful work from the Douglas lab. Give it a read!
jenscs83.bsky.social
Jens Schmidt @jenscs83.bsky.social · Jan 2
Really cool work, demonstrating TRF2-RAP1 mediated inhibition of the NHEJ machinery at chromosome ends!

www.biorxiv.org/content/10.1...
Chromosome end protection by RAP1-mediated inhibition of DNA-PK
During classical non-homologous end joining (cNHEJ), DNA-dependent protein kinase (DNA-PK) encapsulates free DNA ends, forming a recruitment platform for downstream end-joining factors including Ligas...
www.biorxiv.org
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