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Reposted by Karim Majzoub

Harmit Singh Malik @harmitmalik.bsky.social · 1d

Thank you to @viroscope.bsky.social and @carogoujon.bsky.social for nicely answering the very important question I’ve been receiving after more than a decade of seminars.

And the mechanism…

Quelle surprise!!! 😮 🤩

Caro Goujon @carogoujon.bsky.social · 1d

After years in the making, Joe McKellar @viroscope.bsky.social’s final PhD paper is finally out today in PNAS! 🎉 🎉🎉
www.pnas.org/doi/10.1073/...

Human MX1 orchestrates the cytoplasmic sequestration of neosynthesized influenza A virus vRNPs | PNAS

Interferon-inducible Myxovirus resistance 1 (MX1) proteins are known to restrict influenza A virus (IAV) transcription/replication process. Herein,...

www.pnas.org

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Karim Majzoub @karimaj.bsky.social · 1d

Meet us in 2 days in Montpellier for the French-Japan Virology symposium!

Karim Majzoub @karimaj.bsky.social · 21d

Meet us at Genopolys , Montpellier for a France-Japan virology workshop ! 9-10 october 2025 ! 2 exciting days with many viruses! Co-organized with @systemsvirology.bsky.social Kei Sato and Monsef Benkirane @igmm-montpel.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social

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Reposted by Karim Majzoub

Ryan Flynn @raflynn5.bsky.social · 2d

Lead by postdoc in the lab Ruiqi Ge and in collaboration with Bob Coffey’s lab, we are happy to share rPAL-seq for rapid and sensitive sequencing based profiling of glycoRNAs @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

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Karim Majzoub @karimaj.bsky.social · 4d

Thanks Maria @morielab.bsky.social , first time I heard about this journal/platform was thanks to a paper from your lab ;)

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Karim Majzoub @karimaj.bsky.social · 4d

New paper (micro) from our lab : “No evidence for human or rodent deltavirus replication in yeast”. A collaboration with Dom helmlinger’s lab .

No evidence for human or rodent deltavirus replication in yeast | microPublication

doi.org

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Karim Majzoub @karimaj.bsky.social · 5d

Our @viroscope.bsky.social Joe McKellar interviewed by The-Scientist Magazine ! Look at all these beautiful cells we have in the lab :)

Boa Constrictor Brain Cells Slither into Focus

From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.

www.the-scientist.com

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Reposted by Karim Majzoub

CNRS en Occitanie Est @cnrsoccitanieest.bsky.social · 9d

🧬 𝐋’𝐚𝐫𝐭 𝐝𝐞́𝐥𝐢𝐜𝐚𝐭 𝐝𝐞 𝐟𝐚𝐢𝐫𝐞 𝐭𝐚𝐢𝐫𝐞 𝐥𝐞𝐬 𝐠𝐞̀𝐧𝐞𝐬
Des scientifiques de l'IGMM utilisent l’embryon de drosophile pour démontrer que la répression de l’expression des gènes est un mécanisme beaucoup plus complexe qu’attendu.

📖 👉 lnkd.in/dPqUREuf
📷 © Mounia Lagha et Virginia Pimmett

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Reposted by Karim Majzoub

Karim Majzoub @karimaj.bsky.social · 21d

Meet us at Genopolys , Montpellier for a France-Japan virology workshop ! 9-10 october 2025 ! 2 exciting days with many viruses! Co-organized with @systemsvirology.bsky.social Kei Sato and Monsef Benkirane @igmm-montpel.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social

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Reposted by Karim Majzoub

Andrian Gajigan @adi-gajigan.bsky.social · 21d

Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail
nature.com/articles/s41467-025-63463-6

Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail - Nature Communications

Rodrigues and Queiroz et al. report the discovery of Naiavirus, the largest enveloped virus, isolated from a Brazil biome. With an oval capsid and flexible tail, its giant genome holds many novel gene...

nature.com

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Karim Majzoub @karimaj.bsky.social · 21d

Registration link : www.eventbrite.com/e/billets-st...

Strengthening France-Japan Collaboration in Virology

Let's come together to boost collaboration between France and Japan in the field of virology!

www.eventbrite.com

Karim Majzoub @karimaj.bsky.social · 21d

Meet us at Genopolys , Montpellier for a France-Japan virology workshop ! 9-10 october 2025 ! 2 exciting days with many viruses! Co-organized with @systemsvirology.bsky.social Kei Sato and Monsef Benkirane @igmm-montpel.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social

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Reposted by Karim Majzoub

Sofya Garushyants @garushyants.bsky.social · 23d

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

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Karim Majzoub @karimaj.bsky.social · 25d

Endogenous Deltaviruses (EVEs) in termite genomes !

Endogenous viral elements in termite genomes reveal extensive diversity of deltaviruses and provide insights into their origins

Deltaviruses are subviral agents of animals, which, in humans, require a hepadnavirus helper for transmission. The absence of deltavirus-like endogeno…

www.sciencedirect.com

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Karim Majzoub @karimaj.bsky.social · 29d

Student hostages in culture war | EMBO reports

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

www.embopress.org

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Karim Majzoub @karimaj.bsky.social · Sep 8

RIP

Cynthia Wolberger @cwolberger.bsky.social · Sep 8

A giant in molecular biology and virology has passed. RIP David Baltimore.

www.nytimes.com/2025/09/07/s...

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

www.nytimes.com

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Reposted by Karim Majzoub

Joe Bak-Coleman @jbakcoleman.bsky.social · Sep 6

Get fucked, textbooks.

Seriously breaking my PhD in ecology and evolutionary biology brain that this happened.

www.nature.com/articles/s41...

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Reposted by Karim Majzoub

Doudna Lab @doudna-lab.bsky.social · Aug 22

New pre-print from Doudna lab members @erinedoherty.bsky.social & @jnoms.bsky.social ✨

Here we explore how recurrent adaptation of a single anti-defense protein fold enables evasion of distinct immune systems.

Erin Doherty @erinedoherty.bsky.social · Aug 22

Excited to share our new preprint co-led by @jnoms.bsky.social!

Here we reveal an exceptional diversity of viral 2H phosphodiesterases (PDEs) that enable immune evasion by selectively degrading oligonucleotide-based messengers. This 2H PDE fold has evolved striking substrate breath & specificity.

Divergent viral phosphodiesterases for immune signaling evasion

Cyclic dinucleotides (CDNs) and other short oligonucleotides play fundamental roles in immune system activation in organisms ranging from bacteria to humans. In response, viruses use phosphodiesterase...

www.biorxiv.org

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Reposted by Karim Majzoub

Nature @nature.com · Aug 12

Nature research paper: RNA N-glycosylation enables immune evasion and homeostatic efferocytosis

go.nature.com/41x3bol

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis - Nature

N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network without inducing autoinflammatory responses.

go.nature.com

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Reposted by Karim Majzoub

Kranzusch Lab @kranzuschlab.bsky.social · Aug 12

Mining Iguana cDNAs for new immune proteins! Incredibly creative screen from Ian Boys and @elearlybird.bsky.social :

www.biorxiv.org/content/10.1...

A trove of antiviral TRIM family E3 ligases in reptiles

Many scaled reptiles (squamates) are exposed to flaviviruses but some, including iguanas, exhibit strong resistance to infection. To identify genes encoding viral resistance, we screened a cDNA librar...

www.biorxiv.org

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Karim Majzoub @karimaj.bsky.social · Aug 6

Incredible discovery ! The first known role for sugar coated RNAs : immune evasion ! @raflynn5.bsky.social does it angain with @vinnieviruses.bsky.social @vijayrathinam.bsky.social and colleagues !

Ryan Flynn @raflynn5.bsky.social · Aug 6

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

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Reposted by Karim Majzoub

Ryan Flynn @raflynn5.bsky.social · Aug 6

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

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Karim Majzoub @karimaj.bsky.social · Jul 25

Congrats

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Karim Majzoub @karimaj.bsky.social · Jul 7

Proud of Roni , a PhD student from our lab !

IGMM-Montpellier @igmm-montpel.bsky.social · Jul 7

Félicitations à Roni Sleiman !
Médaille d’argent à la Journée Infectiopole Sud 2025
pour sa présentation : “Unraveling Deltavirus Nuclear Exit and Assembly”.
🎉 Prix de 500 €, remis à l’IHU Méditerranée, Marseille.
@karimaj.bsky.social

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Reposted by Karim Majzoub

Dame lab at Leiden University @damelab.bsky.social · Jun 30

A must-read for histone afficionados: our new review on 'Histone-mediated chromatin organization in prokaryotes and viruses' www.cell.com/trends/bioch... @samuelschwab.bsky.social @vikramalva.bsky.social

Histone-mediated chromatin organization in prokaryotes and viruses

Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

www.cell.com

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Reposted by Karim Majzoub

New Scientist @newscientist.com · Jul 7

Beware the tech leaders making grandiose statements about artificial intelligence. They have lost sight of reality, says Philip Ball

The dangers of so-called AI experts believing their own hype

Beware the tech leaders making grandiose statements about artificial intelligence. They have lost sight of reality, says Philip Ball

www.newscientist.com

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