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Reposted by David J. Herzfeld

mchurchland.bsky.social @mchurchland.bsky.social · Sep 8

Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...

Motor cortex flexibly deploys a high-dimensional repertoire of subskills

Skilled movement often requires flexibly combining multiple subskills, each requiring dedicated control strategies and underlying computations. How the motor system achieves such versatility remains u...

www.biorxiv.org

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Reposted by David J. Herzfeld

Anne West @ennatsew.bsky.social · Jul 27

The Anne West lab at Duke is hiring a postdoc to work on nuclear cell biology in neurogenesis. Please help me spread the word! Applications to [email protected].

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Reposted by David J. Herzfeld

Nature Reviews Neuroscience @natrevneuro.nature.com · Jun 18

Cerebellar circuit computations for predictive motor control — a Review by Katrina P. Nguyen & Abigail L. Person

www.nature.com/articles/s41...

#neuroscience #neuroskyence

Cerebellar circuit computations for predictive motor control - Nature Reviews Neuroscience

The cerebellum helps ensure the speed and accuracy of movements, but its precise contributions to movement control are unclear. Nguyen and Person here evaluate evidence for and against feedforward mot...

www.nature.com

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David J. Herzfeld @dherzneuro.bsky.social · Jun 8

I feel very lucky in this regard - I will have already hired a fantastic lab manager with 10+ years NHP experience, and who seems to be willing to stay (fingers crossed) for the long haul!

Can't ask for better.

But I also need additional "hands" (beyond mine) to do the science.

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David J. Herzfeld @dherzneuro.bsky.social · Jun 8

My point exactly. I'm not sure how long to wait for the "right person" given that some portion of my startup expires soon-ish (3+ years).

David J. Herzfeld @dherzneuro.bsky.social · Jun 8

This is fantastic advice!

For whatever reason, I feel obligated to hire someone quickly if I put out an ad - obviously not the case (given my faculty interviews...!).

It sounds like the message is to put out multiple ads and wait for the best person/fit.

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David J. Herzfeld @dherzneuro.bsky.social · Jun 8

I received similar advice, but not sure how I can reasonably hire people if I can't guarantee them a long(ish) term position.

My PIs have been very generous with timelines. I would like to be similarly in a position to keep good people - especially when timing for their next position is unknown.

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David J. Herzfeld @dherzneuro.bsky.social · Jun 8

We have to explicitly advertise for a particular position (only post-doc/tec).

I would love to just evaluate based on fit and talent, but at least at the "professional" level, I have to explicitly specify the level/experience/salary.

So, multiple calls? But no commitments to hiring?

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David J. Herzfeld @dherzneuro.bsky.social · Jun 8

My established scientists, two incredibly "new PI" questions:

1. How do you figure out how many people to hire/can hire? What's the math based on $ in account and when those $ expire?

2. How do you figure out your ratio of techs, grad students, and post-docs? Is it project or budget based?

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Reposted by David J. Herzfeld

Amanda Therrien @amandastherrien.bsky.social · Apr 16

POSTDOC JOB OPENING. My lab at @mossresearch.bsky.social has an opening for a postdoc fellow to work with @aaronlwong.bsky.social and me on an NSF-funded research program studying mechanisms of sensory plasticity that accompany adaptive motor learning. The full posting is below. Please share!

Full job posting for a postdoc position at the Jefferson Moss Rehabilitation Research Institute.

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Reposted by David J. Herzfeld

Aaron L Wong @aaronlwong.bsky.social · Apr 16

Come work with us! Amanda is a fantastic advisor, and we have some really exciting studies planned!

Amanda Therrien @amandastherrien.bsky.social · Apr 16

POSTDOC JOB OPENING. My lab at @mossresearch.bsky.social has an opening for a postdoc fellow to work with @aaronlwong.bsky.social and me on an NSF-funded research program studying mechanisms of sensory plasticity that accompany adaptive motor learning. The full posting is below. Please share!

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Reposted by David J. Herzfeld

Philip Sabes @psabes.bsky.social · Mar 28

Are you an ambitious scientist or engineer?
Do you want to do hard engineering that will transform lives and advance science?
Come join us to build next-generation neurotechnology at Integral.

Integral @integralneuro.bsky.social · Mar 26

We're hiring again.

- EEs
- MechEs
- BiomedEs
- ASIC designers
- and more...

www.integralneuro.com/careers

Careers | Integral

Integral is building technologies to treat neurological and psychiatric disorders.

www.integralneuro.com

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David J. Herzfeld @dherzneuro.bsky.social · Mar 3

I believe there was an update today (3/3/25)! The announcement is currently listed as "pending," scheduled to be officially posted 3/4. It lists review meetings for the DP2, Transformative Research Awards, and PBKD.

Link here: www.federalregister.gov/public-inspe...

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Reposted by David J. Herzfeld

Maxime Beau @maxime-beau.bsky.social · Mar 1

I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.ce... 1/16 🧵

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David J. Herzfeld @dherzneuro.bsky.social · Feb 28

We think that our approach can be generalized to other brain areas - allowing links from neurons to circuits to behavior.

And...our automated tool can be used right now by other cerebellar researchers!

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David J. Herzfeld @dherzneuro.bsky.social · Feb 28

We certainly learned lots of lessons from this paper (e.g., need for standardizing pre-processing across labs and incredibly careful data curation, necessity of pharmacological blockade for opto-tagging in cerebellum, nearly complete inability to record granule cells using conventional probes).

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David J. Herzfeld @dherzneuro.bsky.social · Feb 28

We are very excited to see our collaborative paper on classification of neuron types in the cerebellum (across species!) now published in Cell.

www.cell.com/cell/fulltex...

This was a huge project, spanning multiple labs - across continents - and a huge team effort!

A deep learning strategy to identify cell types across species from high-density extracellular recordings

We constructed a deep learning classifier that solves the problem of neuron-type identification from simultaneous extracellular recordings of many neurons. The classifier was trained on a ground-truth...

www.cell.com

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

Thanks, Andrew!

David J. Herzfeld @dherzneuro.bsky.social · Feb 23

And - another personal plug: I am setting up my lab at UW-Madison this summer (herzfeldlab.neuro.wisc.edu). I am looking for people passionate about linking circuit computations to behavior in primates! (6/6)

Herzfeld Lab

Herzfeld Lab at UW-Madison: Herzfeld Lab

herzfeldlab.neuro.wisc.edu

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

We hope that this work inspires others to perform similar circuit dissection analyses in other regions of the cerebellum (and beyond)! (5/6)

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

Along the way, we demonstrate the requisite properties of granule cell responses (a cerebellar neuron whose activity is invisible to current multi-contact electrodes). (4/6)

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

Using these neuron-identification tools, we characterize the input-output computations performed by the cerebellum and go on to show how (and where) the cerebellar circuit implements these computations. Long-story short, the cerebellum implements temporal and directional transformations. (3/6)

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

We take advantage of some new tools we developed to distinguish neuron types within the cerebellum from extracellular recordings (doi.org/10.1101/2025... & doi.org/10.1101/2024...) in a region that is crucial for the execution of smooth eye movements (the floccular complex). (2/6)

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David J. Herzfeld @dherzneuro.bsky.social · Feb 23

I'm thrilled to share our new *NIH funded* paper (doi.org/10.1101/2025...) describing the circuit-level computations performed by the cerebellum during eye movements in primates. (1/6)

Neural circuit mechanisms to transform cerebellar population dynamics for motor control in monkeys

We exploit identification of neuron types during extracellular recording to demonstrate how the cerebellar cortex's well-established architecture transforms inputs into outputs. During smooth pursuit ...

doi.org

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Reposted by David J. Herzfeld

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Jan 29

Strategies to decipher neuron identity from extracellular recordings in the cerebellum of behaving non-human primates https://www.biorxiv.org/content/10.1101/2025.01.29.634860v1

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