dijo-mj.bsky.social
dijo_mj
@dijo-mj.bsky.social
12 followers 11 following 2 posts
Doctoral Researcher at Max Planck Institute for the Science of Light, Erlangen, Germany
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lmoeckl.bsky.social
Leonhard Möckl @lmoeckl.bsky.social · 6d
NEW PREPRINT: Spatial mapping of cell-surface protein glycosylation at molecular resolution 🍭🍬🔬
For the first time, we can analyze the spatial architecture of the cell-surface glycoproteome at single-protein and single-sugar resolution. #glycotime

www.biorxiv.org/content/10.1...
Spatial mapping of cell-surface protein glycosylation at molecular resolution
Cell-surface protein glycosylation is a fundamental post-translational modification that plays a crucial role in membrane protein function and cellular behavior. However, elucidating the molecular spa...
www.biorxiv.org
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dijo-mj.bsky.social
dijo_mj @dijo-mj.bsky.social · Sep 1
Won the best poster award :) at #SMLMS2025 @smlm-symposium.bsky.social together with Sanne Giezen. Thanks to my mentor @lmoeckl.bsky.social and colleague @nazlicanyurekli.bsky.social and all the members of Möckl lab.
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dijo-mj.bsky.social
dijo_mj @dijo-mj.bsky.social · Sep 1
Attended #SMLMS2025 last week in Bonn, Germany. Many thanks to the organizers @uendesfelder.bsky.social @heilemannlab.bsky.social and Prof. Kubitscheck for introducing #youngSMLMS. That was really mindful of the young researchers including me:). Had a great time in Bonn discussing science.
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lmoeckl.bsky.social
Leonhard Möckl @lmoeckl.bsky.social · Jul 28
Very happy to see this one out - the first molecular-resolution imaging of glycocalyx components in their native environment! Great collaboration with @jungmannlab.bsky.social - congrats to first authors @karimalmahayni.bsky.social and @lumasullo.bsky.social and to the whole team!
natnano.nature.com
Nature Nanotechnology @natnano.nature.com · Jul 28
New paper online:

Ångström-resolution imaging of cell-surface glycans.

The molecular organization of sugars in the native #glycocalyx has been resolved at 9 ångström using bioorthogonal metabolic labeling and #superresolution imaging of DNA barcodes.

#Glycotime

www.nature.com/articles/s41...
Ångström-resolution imaging of cell-surface glycans - Nature Nanotechnology
By combining bioorthogonal metabolic labelling and resolution enhancement through sequential imaging of DNA barcodes, the molecular organization of individual sugars in the native glycocalyx has been ...
www.nature.com
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Reposted by dijo_mj
lmoeckl.bsky.social
Leonhard Möckl @lmoeckl.bsky.social · May 2
GLYCAN ATLASSING: NANOSCALE ANALYSIS OF GLYCOCALYX ARCHITECTURE ENABLES FUNCTIONAL TRACING OF CELL STATE 🍭🔬🧬
Don’t judge a book by its cover - judge a cell by its cover! We can now trace how cell state is encoded in glycocalyx state. #glycotime #microscopy

www.biorxiv.org/content/10.1...
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