Dirk Metzler
@dirkmetzler.bsky.social
140 followers 180 following 6 posts
stochastic modelling in biology, evolutionary bioinformatics, theoretical population genetics, evolutionary (epi)genomics and transcriptomics
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Reposted by Dirk Metzler
wetter-center.de
Die EU-Kommission will Messenger-Dienste zwingen, ALLE privaten Nachrichten und Fotos in Echtzeit zu scannen. Die #Chatkontrolle bedeutet das Ende von verschlüsselter Kommunikation. Das verstößt gegen unsere Grundrechte. Jetzt dagegen unterzeichnen: 👇
Chatkontrolle stoppen!
Die EU-Kommission will Messenger-Dienste wie WhatsApp und Signal zwingen, alle privaten Nachrichten und Fotos in Echtzeit zu scannen. Angeblich zum Kinderschutz. In Wahrheit bedeutet die Chatkontrolle...
weact.campact.de
Reposted by Dirk Metzler
jbonfield.bsky.social
Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned
Reposted by Dirk Metzler
yun-s-song.bsky.social
SINGER, our ARG inference method, is finally published and freely available online:

doi.org/10.1038/s415...

It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...
Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes - Nature Genetics
SINGER is a method for creating ancestral recombination graphs to understand the genealogical history of genomes. The method has increased speed, and thus scalability, without sacrificing accuracy.
doi.org
Reposted by Dirk Metzler
gevol.bsky.social
Many thanks to all GEvol members for a truly wonderful annual meeting. It was really great to catch up with you all again.
Reposted by Dirk Metzler
dingemanselab.bsky.social
Congrats Dr. @roriwijnhorst.bsky.social @lmumuenchen.bsky.social for an impressive PhD-presentation and defence. Thanks partner in crime @cdegroot.bsky.social and collaborators @ali--wilson.bsky.social, Henrik Jensen & Jon Wright and @dfg.de for funding his project on social evolution in sparrows
Reposted by Dirk Metzler
lmumuenchen.bsky.social
Two #LMU projects receive ERC #ProofOfConcept Grants!
🌿 Silke Robatzek is pursuing a novel approach in plant protection strategies.
🧠 @tobiasstaudigl.bsky.social optimizes deep brain stimulation with functional markers.
#LMU #ERC #ResearchInThePractice Read more here: www.lmu.de/en/newsroom/...
dirkmetzler.bsky.social
We are quite delighted by the media coverage of our paper:

This Jungle Plant Is a Good Landlord to Its Tenant Ants www.nytimes.com/2025/07/10/s...
This Jungle Plant Is a Good Landlord to Its Tenant Ants
www.nytimes.com
Reposted by Dirk Metzler
mmlopezu.bsky.social
🧬 Shift between specialized & generalized diets in #bees is associated with evolutionary changes in their sensory genes. Generalists lose odorant receptors (ORs) and gain gustatory receptors (GRs), while specialists diversify existing genes 🌸🐝 #genomics #pollinators
academic.oup.com/g3journal/ad...
Shifts in bee diet breadths are associated with gene gains and losses and positive selection across olfactory receptors
Abstract. Bees are palynivorous insects that vary widely in the number of plant families from which they collect pollen. Their evolutionary history has bee
academic.oup.com
Reposted by Dirk Metzler
chyiyin.bsky.social
Despite their strikingly different plumage, carrion and hooded crows show strong asymmetrical gene flow hidden beneath the feathers #hybridzone #evolution #demography #bird

onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
dirkmetzler.bsky.social
Further, we found – at least for a range of model parameter values – that the defence trait is indeed altruistic. That is, it reduces the direct fitness of the defender, such that, from the perspective of inclusive fitness theory, kin selection really matters.
dirkmetzler.bsky.social
Can genetic drift generate enough variation between subpopulations to allow for the evolution of defence against predators or parasites via multi-level selection? In www.sciencedirect.com/science/arti... we have explored this for a structured population model.
Selection for altruistic defense in structured populations
We model natural selection for or against an anti-parasite (or anti-predator) defense allele in a host (or prey) population that is structured into ma…
www.sciencedirect.com
Reposted by Dirk Metzler
official-smbe.bsky.social
👏 Congratulations to the organization of the SMBE satellite meeting on 'Origin, Maintenance, and Evolution of Biological Noise' that was held in Tübingen!
luisapallares.bsky.social
Thanks to all who came to Tübingen to discuss about Biological Noise, where does it come from, how does it evolve, and what role it plays in phenotypic diversity. We had great discussions despite the not so great weather! Special thanks to @official-smbe.bsky.social for funding it! #BioNoise