edvardmoser.bsky.social
Edvard I Moser
@edvardmoser.bsky.social
1.5K followers 110 following 26 posts
Scientific Co-Director and Professor at Kavli Institute for Systems Neuroscience, NTNU, Norway. Neural network computation, grid cells. Nobel Prize Physiology-Medicine 2014.
Posts Media Videos Starter Packs
Pinned
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Jun 26
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)

👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
www.science.org
5 58 210
Reposted by Edvard I Moser
clykken.bsky.social
clykken.bsky.social @clykken.bsky.social · 14d
1/8
How can the brain create countless unique memories using a single, universal metric of space? We’ve been waiting for the answer to this for two decades!
Read it here:
www.biorxiv.org/content/10.1...
2 22 56
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · 14d
5/5 Big thanks to the team and collaborators @clykken.bsky.social @beneuroscience.bsky.social @anagelhus.bsky.social @jocarpenter.bsky.social @matteoguardamagna.bsky.social @m-bmoser.bsky.social @kavlintnu.bsky.social
#Neuroscience #GridCells #PlaceCells #EpisodicMemory #Neuropixels #KiloNeurons
8
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · 14d
4/5 Conclusion: Independent phase changes across grid modules are sufficient to generate a vast array of distinct hippocampal representations.

Why this matters: Such combinatorial flexibility is a key requirement for forming episodic memories, offering a mechanism for high-capacity memory.
1 9
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · 14d
3/5 We discovered that when grid cell modules realigned differently between environments, hippocampal place cells remapped. Strikingly, the extent of this remapping was directly predicted by the disparity in phase changes across grid modules.
1 7
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · 14d
2/5 After two decades, our hypothesis for this space-to-memory transformation finally met a decisive test.
Led by our outstanding postdoc @clykken.bsky.social, we performed multi-area #Neuropixels recordings simultaneously from hippocampal place cells and multiple MEC grid cells modules in rats 🧠
1 7
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · 14d
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵
Preprint link 👇

www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
www.biorxiv.org
1 16 68
Reposted by Edvard I Moser
bernsteinneuro.bsky.social
Bernstein Network Computational Neuroscience @bernsteinneuro.bsky.social · Jul 17
In case you still need a reason to attend the #BernsteinConference, let us remind you of this year's great speaker line-up 🤩

First up is Nobel laureate @edvardmoser.bsky.social!

Be part of the bridge -- registration is open! 👉 bernstein-network.de/bernstein-co...
A portrait photo of Edvard Moser, next to it the following quote: "I am excited to participate at this conference, a major venue for bridging theory and experiment. Those bridges are vital to the progress of neuroscience."
2 10
Reposted by Edvard I Moser
trose-neuro.bsky.social
Tobias Rose @trose-neuro.bsky.social · 29d
BonnBrain 2026 is a go!
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.

Keynotes & invited speakers 👇
1 16 27
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Aug 13
Excellent work, and very interesting observations - congratulations!
1
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Aug 9
So beautiful up there, only 58 min to the trailhead!
m-bmoser.bsky.social
May-Britt Moser @m-bmoser.bsky.social · Aug 9
Storskarven 🤩
1 17
Reposted by Edvard I Moser
m-bmoser.bsky.social
May-Britt Moser @m-bmoser.bsky.social · Aug 9
Storskarven 🤩
2 1 25
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Jun 26
🧠⏳ This discovery would not be possible without #Neuropixels and the dedication and talent of @beneuroscience.bsky.social @clykken.bsky.social @nachopolti.bsky.social @m-bmoser.bsky.social at the @kavlintnu.bsky.social (2/2)
ky.social
1 14
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Jun 26
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)

👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
www.science.org
5 58 210
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Apr 9
Kudos to Minister Sigrun Aasland @kd.regjeringen.no for scrapping the language requirement for international PhD students and postdocs. I was interviewed by @nature.com about this decision that strengthens recruitment in a country where 75% of postdocs are from abroad. www.nature.com/articles/d41...
Norway set to scrap mandatory language training for foreign postdocs and PhD students
Researchers jubilant over swift ministerial response to rule they say would hamper international recruitment.
www.nature.com
4 16
Reposted by Edvard I Moser
m-bmoser.bsky.social
May-Britt Moser @m-bmoser.bsky.social · Feb 12
There is hope! 💃🏻

www.khrono.no/statsrad-aas...
1 2 9
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 12
I was interviewed by @nature.com about the risk of talent exodus following Norway’s new language law. I hope the new government and science minister will change the internationalisation policy ASAP.
@stortinget.no, @uhrno.bsky.social, @forskningspolitikk.bsky.social

www.nature.com/articles/d41...
Scientists fight Norway’s language law, warning of talent exodus
Mandatory language courses for foreign researchers could harm Norway’s ability to attract the best talent, Nobel laureate says, as rule prompts legal challenge.
www.nature.com
3 21
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 8
This could be catastrophic. Consequences for US universities (and the world) may be beyond imagination.
carlbergstrom.com
Carl T. Bergstrom @carlbergstrom.com · Feb 8
1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
1 8 30
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 8
Looking forward - opens so many doors!
carandinilab.net
Matteo Carandini @carandinilab.net · Feb 7
Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.
14
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Thanks! Not merely expressing future trajectories. The sweeps also extend into spaces not visited, and persist during sleep.
2
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Sweeps represent an efficient mechanism for scanning locations in the ambient environment during navigation. Sweep direction could be explained by an algorithm that maximizes cumulative coverage of surrounding space.
1 1 8
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Sweeps in place cells are delayed compared to sweeps in grid cells, pointing to an entorhinal origin. 📍
1 9
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Sweeps are accompanied by, and aligned with, a similarly alternating directional signal in a discrete population of direction-tuned cells with putative connections to the #gridcells 🗺️
1 6
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Sweeps extend into never-visited space inaccessible to the animal, and persist during REM sleep, pointing to an intrinsic “hardwired” network mechanism for the phenomenon. 🧹🌋🧹🌊🧹
1 1 7
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Sweeps are time-locked to the local theta rhythm. Each theta cycle has one sweep. Sweeps alternate their direction between left and right on successive theta cycles.
1 6
edvardmoser.bsky.social
Edvard I Moser @edvardmoser.bsky.social · Feb 3
Populations of grid cells and place cells encode a position signal that within a 125-ms theta cycle sweeps linearly outwards from the animal’s location into the ambient environment, alternating stereotypically between left and right directions. 🧹🧹🧹
1 8