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Eleanna @eleannak.bsky.social · 24d

Pleased to present the unboxing of our lab’s labubus! The green macaron named Lewy (after Lewy bodies) has officially decided to join our lab for its PhD thesis and is already learning how to write Python code 🔬 www.instagram.com/share/BAGYdC...

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Eleanna @eleannak.bsky.social · Sep 8

Thank you!

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Eleanna @eleannak.bsky.social · Sep 8

We celebrated the lab’s second anniversary! Proud of our accomplishments so far, including our paper in Cell Reports, several student awards, invited talks and good scores on NIH grants 🥳 Exciting new research is in progress and we will be ready to share it soon 🔬

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Eleanna @eleannak.bsky.social · Aug 21

Congratulations for the amazing study!

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Eleanna @eleannak.bsky.social · Aug 21

www.nature.com/articles/s41...

Quantitative imaging of lipid transport in mammalian cells - Nature

Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.

www.nature.com

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Eleanna @eleannak.bsky.social · Aug 1

Quote of the century from yesterday’s amazing Chan Zuckerberg bio hub Cell Biology at Scale symposium, which is now decorating our lab! 🐈

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Eleanna @eleannak.bsky.social · Jul 29

Lab photo July 2025!

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Eleanna @eleannak.bsky.social · Jul 6

Group imaging on our new confocal! 🔬👩‍🔬🧑‍🔬

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Eleanna @eleannak.bsky.social · Jun 27

Nah, we have to add it manually sadly 🤪 We also limit ourselves to the humble zeiss oil instead of ultra pure olive oil 🫒

Eleanna @eleannak.bsky.social · Jun 27

Adding the first drop of oil to my lab’s new in-house confocal 🤩🔬👩‍🔬

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Eleanna @eleannak.bsky.social · Jun 3

Proud that 2 students in the lab recently received 4 fellowships and awards! Michael David Rothstein Endowed Scholarship; AΩA Carolyn L. Kuckein Student Research Fellowship; Cell Biology & Neuroscience undergraduate research excellence award; Henry Rutgers Scholar Award 🥳

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Reposted by Eleanna

NEJM.org @nejm.org · May 15

A lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F

#ASGCT2025 #MedSky @asgct.bsky.social

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...

nej.md

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Eleanna @eleannak.bsky.social · May 5

Our lab's first paper has been published! www.cell.com/cell-reports...

Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

Eubanks et al. found that gene expression networks that are specific for brain regions that develop high degrees of alpha-synuclein pathology carry an increased frequency of rare risk variants in pati...

www.cell.com

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Eleanna @eleannak.bsky.social · Feb 16

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Reposted by Eleanna

Jascha Polet @jascha.bsky.social · Feb 11

“We have evidence that this is fluid-driven, swarm-type seismicity that comes in pulses. This is not unheard of in other volcanic regions; however, this time it is evolving on top of active faults that complicate the expression of seismicity.”
🧪⚒️

Chris Rowan @allochthonous.bsky.social · Feb 11

🧪⚒️ Use of machine learning algorithms to reliably detect smaller magnitude earthquakes around Santorini:

- Detected swarm about 5 days earlier;
- Located 10 times more earthquakes, which gives us more insight into what is going on.

Artificial intelligence is proving a game changer in tracking the Santorini earthquake swarm - British Geological Survey

An online tool that shows which roads are most likely to cause river pollution is being expanded to assess pollution from agricultural areas.

www.bgs.ac.uk

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Eleanna @eleannak.bsky.social · Feb 11

What is the name of the fault line to which it corresponds? Is it the Amorgos fault line?

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Reposted by Eleanna

Jannes Münchmeyer @jannesmunch.bsky.social · Feb 10

Hi Seismo-Bluesky! I decided to test a pipeline with SeisBench, PyOcto, NonLinLoc, and HypoDD on the Santorini sequence. The level of activity (>4,500 events) is truly stunning! There are repeated bursts migrating backwards and forwards, spreading outwards from a narrow, almost linear channel.

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Reposted by Eleanna

MwahahahahahadScientist @mads100tist.bsky.social · Feb 9

Editors be like:

An image with a half-bust drawing of a monkey. On the first panel, the monkey is relax, uninterested. The words "transcriptomics" can be read. On the second panel, the monkey is active and interested. It's brain is shown with an arrow and NEURON ACTIVATION labeled. The words "SPATIAL transcriptomics" can be read.

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Reposted by Eleanna

André Nadler @nadlerlab.bsky.social · Jan 31

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that.
www.biorxiv.org/content/10.1...

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Reposted by Eleanna

The Science of Parkinson's @scienceofpd.bsky.social · Jan 29

Is anyone else starting to think that its all about cillia?

Researchers report PINK1 knock-out mice display cilia defects & reduced GDNF expression akin to LRRK2 mutant mice

A convergent mechanism for #Parkinsons?
www.pnas.org/doi/10.1073/...

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Reposted by Eleanna

Science News @scinews.bsky.social · Jan 26

Ten simple rules for developing good reading habits during graduate school and beyond

journals.plos.org/ploscompbiol...

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Reposted by Eleanna

Fyodor Urnov @urnov.bsky.social · Jan 16

I started working on genetic therapies for Mendelian disease in 2000 - and in the subsequent 25 years have never seen a disease where the molecular aetiology has undergone as giant an "OH WOW" moment as this.
www.cell.com/cell/fulltex...

Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease

Single-cell measurement of the Huntington’s disease-causing CAG repeat reveals that somatic expansion of this repeat drives pathological changes in neurons, providing insights into disease progression...

www.cell.com

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Reposted by Eleanna

Jake Wintermute @synbio1.bsky.social · Jan 15

This pretty much settles it: we're entering the era of low-cost, on-demand binders for everything

Excited to see what people build now that "inject a llama with some junk and bleed it a month later" is no longer the cutting-edge tech
www.nature.com/articles/s41...

De novo designed proteins neutralize lethal snake venom toxins - Nature

Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...

www.nature.com

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Eleanna @eleannak.bsky.social · Jan 5

www.nejm.org/doi/full/10....

Genetic Analysis of a Sarcoma Accidentally Transplanted from a Patient to a Surgeon | NEJM

Modern concepts of cancer immunology originated from the classic observations by Jensen, Loeb, Tyzzer, and Little in the early years of the 20th century of the rejection of transplanted allogeneic ...

www.nejm.org

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Eleanna @eleannak.bsky.social · Dec 31

Last western blot of 2024!

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