Lightnews — Scholar-powered news

Emmanuel Saliba @emmanuel-saliba.bsky.social · 3h

Group Leader positions at HIRI opened on RNA biology - a fantastic place to work and make groundbreaking discoveries - take the chance!

Jörg Vogel @jorg-vogel-lab.bsky.social · 9h

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

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Reposted by Emmanuel Saliba

Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 14d

Heute haben wir auf dem Würzburger Medizin-Campus das Richtfest unseres neuen #HIRI-Institutsgebäudes gefeiert – gemeinsam mit Bayerns stellv. Ministerpräsidenten Hubert Aiwanger und mehr als 200 Gästen. 🎉

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Reposted by Emmanuel Saliba

Emmanuel Saliba @emmanuel-saliba.bsky.social · 29d

🔔PhD position open. Interested in building competencies in computational biology in spatial transcriptomics? Malte Luecken's lab and I have an open PhD position, part of the Munich School of Data Science.
Application deadline: Sept 26
Link: www.mu-ds.de

MUDS - Helmholtz Information & Data Science Academy

www.mu-ds.de

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Reposted by Emmanuel Saliba

GeroldLab @geroldlab.bsky.social · 27d

Great news. The RSV vaccine will be freely available for newborns from October onwards. Effective protection from the most common cause of severe respiratory tract infection in newborns and toddlers.

Aberle Judith @aberlejudith.bsky.social · 28d

Good news ⭐️ RSV-Schutz mit Nirsevimab, das schwere Atemwegs-Erkrankungen um >80% reduziert, wird ab Oktober allen Neugeborenen kostenlos zur Verfügung stehen

Kinder mit erhöhtem Risiko für schwere Verläufe erhalten die Immunisierung auch vor ihrer zweiten RSV-Saison
science.orf.at/stories/3231...

Für Säuglinge erstmals von Saisonbeginn an

Erstmals steht in Österreich über die gesamte Erkältungssaison von Oktober bis März für alle Säuglinge eine kostenlose Immunisierung gegen RSV zur Verfügung. Kinder, die während dieser Zeit auf die We...

science.orf.at

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Emmanuel Saliba @emmanuel-saliba.bsky.social · 29d

In this project, we aim to develop a multilayer data analysis framework that encompasses time, space, and perturbations to understand disease progression following severe lung injury. Contact me if you're interested in knowing more!

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Emmanuel Saliba @emmanuel-saliba.bsky.social · 29d

🔔PhD position open. Interested in building competencies in computational biology in spatial transcriptomics? Malte Luecken's lab and I have an open PhD position, part of the Munich School of Data Science.
Application deadline: Sept 26
Link: www.mu-ds.de

MUDS - Helmholtz Information & Data Science Academy

www.mu-ds.de

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Emmanuel Saliba @emmanuel-saliba.bsky.social · Sep 4

Congrats Jens. This is really terrific.

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Emmanuel Saliba @emmanuel-saliba.bsky.social · Jul 7

Congrats Alex.

Reposted by Emmanuel Saliba

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · Jun 18

𝔟α𝐜𝐓𝕖Ř𝒾ⒶĹ ＳＨⓐ𝓹Ẹ 丂ħ𝓲ƒ𝓉ⒺⓇร 🦠

Ultra-sensitive RNA-seq and FISH show 𝘉𝘢𝘤𝘵𝘦𝘳𝘰𝘪𝘥𝘦𝘴 𝘵𝘩𝘦𝘵𝘢𝘪𝘰𝘵𝘢𝘰𝘮𝘪𝘤𝘳𝘰𝘯 cells adopt different shapes reflecting distinct gene expression profiles and metabolic specializations

A deliberate survival strategy for the ever-changing gut environment?

www.cell.com/cell-reports...

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Reposted by Emmanuel Saliba

Westermann Lab @westermannlab.bsky.social · Jun 17

Our latest: www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠
Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.

Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium

Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size i...

www.cell.com

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Reposted by Emmanuel Saliba

Dominic Grün @dominicgrun.bsky.social · Jun 2

We have an attractive opening for a tenure-track professorship in Single-Cell Systems Biology. Excellent package and infrastructure at @uni-wuerzburg.de Institute of Systems Immunology. Great place to live and work in the heart of the franconian wine region!

jobs.sciencecareers.org/job/673667/j...

junior professorship position (f/m/d) in Single-Cell Systems Biology - Würzburg (Stadt), Bayern (DE) job with Julius-Maximilians-University Würzburg - Faculty of Medicine | 673667

The Julius-Maximilians-University Würzburg, Faculty of Medicine is offering one junior professorship position (f/m/d) in Single-Cell Systems Biology.

jobs.sciencecareers.org

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Reposted by Emmanuel Saliba

Julius-Maximilians-Universität Würzburg @uni-wuerzburg.de · May 22

Erfolg auf ganzer Linie: zwei Exzellenzcluster für Würzburg! 🥂🚀
Im Rahmen der #ExStra wird nicht nur der Quantenphysik-Cluster ctd.qmat weiterhin gefördert. Mit NUCLEATE, einem Forschungsprojekt zu Nukleinsäuren, kommt noch ein zweiter Cluster hinzu!
➡️ go.uniwue.de/xstra25

Freude über den Doppelerfolg: Zwei Würzburger Forschungsvorhaben haben sich im Exzellenzwettbewerb durchgesetzt und erhalten Mittel aus der begehrten Millionenförderung. Von links: Caroline Kisker (Würzburger Koordinatorin von NUCLEATE und Vizepräsidentin), Cynthia Sharma (Würzburger Speakerin von NUCLEATE), Ralph Claessen (Würzburger Speaker von ctd.qmat) und Universitätspräsident Paul Pauli (Bild: Jonas Blank / JMU)

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Reposted by Emmanuel Saliba

Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · May 8

MATQ-seq allows the detection of a large number of genes per single bacterium and is characterized by a high cell retention rate. 🦠 A #HIRI & @uni-wuerzburg.de research team recently published a step-by-step protocol in @natprot.nature.com.

Learn more ⬇

Julius-Maximilians-Universität Würzburg @uni-wuerzburg.de · May 8

Analysing the gene activity of every single bacterial cell in a colony: A new technique of single-cell #transcriptomics developed with @helmholtz-hiri.bsky.social can do this more efficiently than other methods! Publication @natprot.nature.com
www.uni-wuerzburg.de/en/news-and-...

The cartoon illustrates how single-cell transcriptomics works: all mRNA molecules are recorded and characterized from countless bacterial cells, which are shown here in survival size on a conveyor belt through the laboratory. This reveals which genes are currently active in the individual bacteria. (Image: Scigraphix)

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Reposted by Emmanuel Saliba

Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · Apr 24

Last week's @embo.org Sectoral Meeting on #RNA and Structural Biology, organized by #HIRI's @emmanuel-saliba.bsky.social, was a huge success. A heartfelt thank you to everyone who contributed and participated! 👏🧬 Read more: www.helmholtz-hiri.de/en/newsroom/...

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Reposted by Emmanuel Saliba

Jens Hör @jenshoer.bsky.social · Apr 23

I'm happy to share the first publication from my lab @hoerlab.bsky.social, now out in @narjournal.bsky.social! I take a look at the biology of RNA phages, focusing on how meta-omics methods are discovering new RNA phage families and bacterial defense strategies.

#PhageSky

doi.org/10.1093/nar/...

Advancing RNA phage biology through meta-omics

Abstract. Bacteriophages with RNA genomes are among the simplest biological entities on Earth. Since their discovery in the 1960s, they have been used as i

doi.org

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Reposted by Emmanuel Saliba

Itai Yanai @itaiyanai.bsky.social · Apr 14

My guidelines for exploratory data analysis

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Reposted by Emmanuel Saliba

Anke Sparmann @ankesparmann.bsky.social · Apr 9

Microbial single-cell MATQ-seq developed by @emmanuel-saliba.bsky.social & @jorg-vogel-lab.bsky.social allows detection of a large number of genes per single bacterium & stands out for its high rate of cell retention.
For a detailed protocol, see rdcu.be/eg0Xc, now available @natprot.bsky.social.

Transcriptomic profiling of individual bacteria by MATQ-seq

Nature Protocols - Bacterial single-cell sequencing via MATQ-seq combines index sorting, random priming and rRNA depletion, and offers high cell retention and transcript capture rates, making it...

rdcu.be

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Reposted by Emmanuel Saliba

Jörg Vogel @jorg-vogel-lab.bsky.social · Apr 9

If you want to do single-cell RNA-seq on your favourite bacterium, here‘s our detailed Nature Protocol for microbial MATQ-seq. It profiles up to 600 genes in a single bacterial cell!

www.nature.com/articles/s41...

Transcriptomic profiling of individual bacteria by MATQ-seq - Nature Protocols

Bacterial single-cell sequencing via MATQ-seq combines index sorting, random priming and rRNA depletion, and offers high cell retention and transcript capture rates, making it ideal for experiments wi...

www.nature.com

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Emmanuel Saliba @emmanuel-saliba.bsky.social · Apr 1

"What is the physiological relevance?"

Reposted by Emmanuel Saliba

Andreas Moor @andreasmoor.bsky.social · Mar 24

My lab at ETH has an opening for a Scientist in Antibody & Nanobody Drug Discovery (workspace in Basel, Switzerland). jobs.ethz.ch/job/view/JOP...
Please apply if suitable or RT, thanks!

Scientist – Antibody & Nanobody Drug Discovery

jobs.ethz.ch

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Reposted by Emmanuel Saliba

RNAConnect @rnaconnect.bsky.social · Mar 19

🚨 #ABRF2025 is almost here and RNAConnect is proud to be a Gold sponsor!

RNA challenges like degradation, secondary structures & cDNA bias can compromise your data—UltraMarathonRT helps you overcome them!

📍 Visit booth #509 to learn more!

#ABRF #RNAseq #NGS #RNAResearch #RNASky

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Reposted by Emmanuel Saliba

Typas Lab @typaslab.bsky.social · Mar 20

Don't miss the deadline (1st April) for registering to the New Microbiology Lecture Course in Spetses

Typas Lab @typaslab.bsky.social · Dec 16

You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...

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Reposted by Emmanuel Saliba

Single-Cell Center Würzburg @scc-wurzburg.bsky.social · Mar 11

Pathogens often hide in just a few of a patient's trillion cells. Detecting these cells early & accurately using #singlecell sequencing opens up new possibilities for medicine. How does single-cell analysis work? Take a look at our animation by @scicomlab.bsky.social: www.youtube.com/watch?v=FiF6...

Detect a disease before it emerges? This is how single-cell research may help.

YouTube video by Helmholtz Institute Würzburg (HIRI)

www.youtube.com

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Reposted by Emmanuel Saliba

Single-Cell Center Würzburg @scc-wurzburg.bsky.social · Mar 10

Hello Bluesky! 👋🦋 We are the Single-Cell Center Würzburg and we specialize in #RNA sequencing technologies. Our objective is to analyze & understand diseases at the level of individual cells.

➡️ single-cell-center.de

@helmholtz-hiri.bsky.social @uni-wuerzburg.de @systemsimmunology.bsky.social

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Reposted by Emmanuel Saliba

RNAConnect @rnaconnect.bsky.social · Mar 4

Elevate your gene expression analysis with the uMRT Two-Step RT-qPCR Kit!

Enjoy consistent Ct values & improved data reliability, regardless of RT primer, RNA complexity, or amplicon location.

rnaconnect.com/pages/rt-qpcr

#qPCR #rtqpcr #NGS #RNA #RNASky

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