Evan Brenner
@evanbrenner.bsky.social
120 followers 460 following 6 posts
Postdoc in the JRavi Lab at the University of Colorado, applying machine learning methods to figure out how microbes evolve and what risks they pose to human and animal health. Ask me about bacteria!
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Reposted by Evan Brenner
maxkozlov.bsky.social
🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious.

"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."

Each of them are VOID and ILLEGAL, he says.
Reposted by Evan Brenner
interprodb.bsky.social
🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB!
For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.
CATH-Gene3D annotation visualised on BFVD structure prediction of UniProt A0A075FDU7
Reposted by Evan Brenner
tsbschm.bsky.social
The Koonin Law of Computatoinal Biology:

Whenever you think you have a great idea in computational or evolutionary biology, it will already have been published by Eugene Koonin in the mid 90ies.
Reposted by Evan Brenner
kgandersen.bsky.social
The spread of Mpox in Sierra Leone is unlike anything we have ever seen - and we have been keeping an eye on this bug in the region for >15 years.

Given geographical spread, 50/50 men vs women, this is no "sexual network".

This could be the next one.

clt.npha.gov.sl/outbreak.aspx
Reposted by Evan Brenner
maxkozlov.bsky.social
Who's calling the shots at NIH?

Sworn testimonies and internal e-mails reveal for the first time the breadth of DOGE's control over the world's largest public biomedical funder.

DOGE has provided lists of hundreds of grants to cut, and DOGE is now reviewing ALL NIH awards before they're released
NIH killed grants on orders from Elon Musk’s DOGE
Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.
www.nature.com
Reposted by Evan Brenner
gemmaatkinson.bsky.social
Really excited to share our resource and analysis of AlphaFold-predicted monomers and homodimers across viruses and phages. Project driven by fab PhD student @rodai.bsky.social and with our great collaborators Joana Pereira @joanampereira.bsky.social and @ninjani.bsky.social
biorxiv-molbio.bsky.social
The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes https://www.biorxiv.org/content/10.1101/2025.05.14.653371v1
Reposted by Evan Brenner
zaminiqbal.bsky.social
Delighted to see this paper from danderson123.bsky.social 's PhD out. We have been building tools for AMR gene detection for over a decade now, but multicopy genes remain challenging. Dan shows that with a gene-space de Bruijn graph and long reads, you can do well
www.biorxiv.org/content/10.1...
Reposted by Evan Brenner
petrathepostdoc.bsky.social
an old redraw of one of my fav microbe memes, by @prokaryota.bsky.social

"eAT The DiRT bRöTHer" 🦠

#SciArt #microbes
screenshot of a twitter post, the poster is Elisa Granato @Prokaryota
the picture is the swole and weak shiba meme, the swole shiba on the left says
BACTERIA IN NATURE
eating literal dirt
defying the physical limits of life
this is my third eukaryotic extinction event in a row (raised hands emoji)

the right weak shibe text is
BACTERIA IN THE LAB
not my favourite sugar (three sad smiley emojis)
the pH is off by 0.001
is this tap water? I'm allergic my redraw of Elisa Granato's bacteria meme
left has a buff orange bacteria with massive flagellas and a 10 pack, text says
BACTERIA IN NATURE
eating literal dirt
defying the physical limits of life
this is my third eukaryotic extinction event in a row (raised hands emoji)

the right has a weakly pink brown blobby bacteria with tiny hairs, text says
BACTERIA IN THE LAB
not my favourite sugar (three sad smiley emojis)
the pH is off by 0.001
is this tap water? I'm allergic
Reposted by Evan Brenner
chiaramasnovophd.bsky.social
Having a hard time processing this. HHMI is pausing all competitions. Very demoralizing for early career scientists like me @hhmi.org
Reposted by Evan Brenner
danieltamarit.bsky.social
New vacancy in my team!

PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.

Please repost and share with talented MSc students in #evobio, bioinformatics or related :)

www.uu.nl/en/organisat...

#MEvoSky #MicroSky
Reposted by Evan Brenner
baym.lol
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
A screenshot of the termination notice showing "Outstanding Investigator Grants" A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted
Reposted by Evan Brenner
punkrockscience.bsky.social
Optometrist: you should really probably spend less time on screens

Me, a computational biologist: I’ll… just take that under advisement, shall I?
Reposted by Evan Brenner
beaconbio.bsky.social
Nine cases of Middle East Respiratory Syndrome (MERS) have been reported in Saudi Arabia including two fatalities and a cluster of seven cases linked to healthcare associated transmission.
http://spr.ly/63329Nk0yX
Reposted by Evan Brenner
maxkozlov.bsky.social
BREAKING: Reports that Trump would try to cut NIH's budget by 40% have come true.

The request released moments ago would:
- Cut $18 BILLION to NIH's $47b budget
- Eliminate NIMHD, NCCIH, FIC
- Collapse ICs into five 'focus areas'

There's also a long screed about NIH's deficiencies.
Reposted by Evan Brenner
dangaristo.bsky.social
NEW: Starting May 5, NSF will implement an across-the-board 15% indirect cost rate (mirroring policies at DOE, NIH)

Also, NSF staff expect 341 additional terminations today, bringing the total number of terminations to ~1,380.
Effective May 5, 2025, NSF will apply a standard indirect cost rate not to exceed 15% to all
grants and cooperative agreements awarded to IHEs for which indirect costs are allowable.1 The
awardee is authorized to determine the appropriate rate up to this limit.
Reposted by Evan Brenner
Reposted by Evan Brenner
colincarlson.bsky.social
🦟🦠 NEW! We looked at every experiment going back to the 1960s, and found that mosquitoes are almost certainly not primary or secondary vectors of Oropouche virus - a common claim in both the scientific literature and public health communication. #EpiSky #IDSky 😷🧪

journals.plos.org/plosntds/art...
Vector competence for Oropouche virus: A systematic review of pre-2024 experiments
Oropouche virus has recently become an urgent threat to public health in Central and South America. OROV is mainly transmitted by biting midges; however, some public health agencies and scientific sou...
journals.plos.org
evanbrenner.bsky.social
Congrats Kevin on a well-earned and well-timed career advancement. Best of luck!
Reposted by Evan Brenner
ianholmes.org
This is a lovely thread of self-introductions from members of the compbio/genomics crowd on BlueSky. It feels a bit more friendly and warm than a starter pack
casey.greenelab.com
There are so many people moving over that I'm sure I'm missing folks. Can we make a #compbio / #genomics intro thread to get reacquainted?

I'm at the University of Colorado. I often say that if you pick two of three from #transcriptome, #ML, and #publicdata, my lab is probably interested.
Reposted by Evan Brenner
physgal.bsky.social
Calling all US and Canadian students thinking about graduate studies! Come study science at #SFU in beautiful British Columbia, Canada. Graduate admissions have been reopened. Apply by April 25th. ⚛️ 🧪👩‍🔬🎢 🇨🇦
Reposted by Evan Brenner