In Angomonas, the host and endosymbiont divide in sync. We discovered that ETP2 helps recruit the dynamin-like protein ETP9 to the symbiont division site, revealing a new piece of the host-encoded machinery controlling endosymbiont division.
Beautiful artwork by @anaymaurya.bsky.social 2/2

Out today: New nucleus-encoded component of the endosymbiont division machinery identified in the trypanosomatid Angomonas deanei.
Congrats @anaymaurya.bsky.social and @rudycadenabioevo.bsky.social!!!🎉🎉🎉 1/2
journals.asm.org/doi/10.1128/...

🚨 Save the date! Thrilled to be co-organizing the next iteration of the @embl.org Symposium on the Cellular Mechanics of Symbiosis (📅 March 17-20), w/ @floravincent.bsky.social, @hassansalem.bsky.social & Tom Richards.
www.embl.org/about/info/c...
#EESSymbiosis #Symbiosis #SymbioSky #MicroSky 🦠

Congratulations, @messorensen.bsky.social!

Interesting AI read. 15-23% of uncultivated microbes may engage in symbiotic relationships.

www.biorxiv.org/content/10.1...

By sidestepping the complexities of polycistronic transcription (typical for trypanosomatids like Angomonas) Lena’s new system lays the groundwork for a long-awaited conditional expression platform which will be a game changer for dissecting host-symbiont molecular interactions in real time.

Excited to share that our T7 RNA polymerase-based expression system brings a new level of versatility to Angomonas deanei as a model for studying endosymbiosis!
doi.org/10.1371/jour...

Fantastic news! Congrats!!!🎉

The Nowack lab temporary tattoos have arrived! Time to decide if you're team Paulinella or team Angomonas...

New vacancy in my team!

PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.

Please repost and share with talented MSc students in #evobio, bioinformatics or related :)

www.uu.nl/en/organisat...

#MEvoSky #MicroSky

With their clever setup to visualize ongoing endosymbiotic gene transfers (EGTs), Enrique Gonzalez-Duran, Ralph Bock and team reveal how double-strand break repair limits excessive EGT. Check out their new Nature Plants paper and my News and Views summary! www.nature.com/articles/s41...

If interested in developing a proposal around microbial endosymbionts in protists (Paulinella, Angomonas or other systems), contact me by PM or email. (2/2)

Interested in joining Heinrich Heine University Düsseldorf for a 2-year postdoc project? Next week (May 6-7) the popular HHU Marie S. Curie Master Class takes place again, an online event supporting you to develop a compelling proposal for the MSCA Postdoctoral Fellowship program. (1/2)

Join the GMI as a Junior Group Leader! The GMI is seeking a talented scientist to lead an independent research group, addressing fundamental questions in molecular plant biology. More information is below.

Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6

Thank you!😊

Send your 'friend' over! I'll be happy to discuss!😆

The host-encoded dynamin-like protein ETP9 forms a contractile ring around the endosymbiont. ETP9 knock down results in division-impaired, filamentous endosymbionts before cells eventually die. 2/2

Out today: Exciting intermediate between endosymbiont and organelle identified! Endosymbionts in Angomonas deanei lost nearly all bacterial cell division genes. Instead, we identified a host-encoded protein, ETP9, that became specialized for endosymbiont division. 1/2
www.science.org/doi/10.1126/...