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pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬
@pilhoferlab.bsky.social
1.6K followers 630 following 42 posts
Microbial cell-cell interactions | contractile injection systems | cytoskeleton | evolution | multiscale imaging | ETH Zürich - run by lab members -
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pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · Mar 21
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
Credit: Margot Riggi (@margotriggi.bsky.social), Max-Planck Institute of Biochemistry (@mpibiochem.bsky.social)
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pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 3h
🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social[email protected] trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...
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pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 5h
Congrats🥳 to @mike-wieczorek.bsky.social, Bin Cai, and our former lab member Jingwei Xu @xujwet.bsky.social to their multiscale imaging 🔬 story of the centriolar AC linker #teamtomo
www.science.org/doi/10.1126/...
Structure and assembly of the A-C linker connecting microtubule triplets in centrioles
Multiscale cryo-EM of centrioles reveals the structure and polymorphism of the A-C linker connecting microtubule triplets.
www.science.org
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Reposted by Pilhofer Lab 🦠❄️🔬
embo.org
EMBO @embo.org · 1d
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.

Deadline: 20 December 2025

https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Structure and Function of the Cytoskeleton
The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …
meetings.embo.org
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daumlab.bsky.social
The Daum Lab @daumlab.bsky.social · 2d
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
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qiangguo.bsky.social
qiangguo.bsky.social @qiangguo.bsky.social · 3d
What's the role of stress granules in translation? Here we provide a clue: we characterized the distribution of ribosomal complexes within SGs and reproduced this landscape with a phase-field model, pointing to a new regulatory mechanism. #TEAMTOMO www.science.org/doi/10.1126/...
Translation landscape of stress granules
Cryo–electron tomography visualizes stress granules in situ, revealing their spatial interplay with translation machinery.
www.science.org
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erinrgreen.bsky.social
Erin Green @erinrgreen.bsky.social · 4d
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
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cryoempapers.bsky.social
cryoEM papers @cryoempapers.bsky.social · 19d
Correlative MS Imaging for cellular identification and analysis of in situ cryo-ET www.biorxiv.org/content/10.1101/2025.09.16.676641v1 #cryoem
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jcamthrash.bsky.social
Cameron Thrash @jcamthrash.bsky.social · 6d
A new paradigm for outer membrane protein biogenesis in the Bacteroidota www.nature.com/articles/s41... #jcampubs
A new paradigm for outer membrane protein biogenesis in the Bacteroidota - Nature
Structural and biochemical studies of the β-barrel-assembly machinery from Flavobacterium johnsoniae reveal a subunit composition and assembly that are distinct from those of the canonical Escherichia coli complex.
www.nature.com
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cellarchlab.com
Ben Engel @cellarchlab.com · 8d
EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬

The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓
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samreckpeterson.bsky.social
Samara Reck-Peterson @samreckpeterson.bsky.social · 9d
We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...
Join our Faculty | Department of Biochemistry & Biophysics
Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...
biochem.weill.cornell.edu
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biozentrum.unibas.ch
Biozentrum, University of Basel @biozentrum.unibas.ch · 9d
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
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lalouxlab.bsky.social
Géraldine Laloux @lalouxlab.bsky.social · 13d
📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...
Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
www.biorxiv.org
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pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 13d
Huuge congrats 🥳🍸 to our friends, collaborators and former colleagues in the Matos Lab
www.maxperutzlabs.ac.at/news/latest-...
maxperutzlabs.ac.at
Max Perutz Labs Vienna @maxperutzlabs.ac.at · 13d
Paper alert! 📢 How do cells strike the perfect balance during meiosis? ⚖️ A new study from the Matos lab in @natureportfolio.nature.com uncovers how Holliday junctions and the synaptonemal complex safeguard crossovers ➡️ tinyurl.com/2k4mmpzu

@univie.ac.at
@meduniwien.ac.at
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nexperion.net
Guenter Resch @nexperion.net · 15d
Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit
www.nexperion.net/semcm2026
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enningalab.bsky.social
Enninga Lab @enningalab.bsky.social · 20d
🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1
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cellarchlab.com
Ben Engel @cellarchlab.com · 16d
Huntingtin protein bound to actin filaments. I didn’t know it could do that! Nice one @schurlab.bsky.social and friends! 🧪🧶🧬 #TeamTomo
istaresearch.bsky.social
Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 16d
Cryo-ET visualization of HTT bound to F-actin, highlighted in the yellow square on the left.
On the right, a detailed zoom-in view of the molecular model of the HTT/F-actin complex is shown.
📷 © Florian Schur
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mishakudryashev.bsky.social
Misha Kudryashev @mishakudryashev.bsky.social · 16d
We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.

We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography

zenodo.org/records/1717...
Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles
zenodo.org
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cellarchlab.com
Ben Engel @cellarchlab.com · 18d
A molecular-resolution look into the near-native architecture of the spinach chloroplast🌱. This one was a long time in the oven, but we're happy to finally share our "version of record". What long-standing debates did we settle? Check back for a short thread🧵 on Monday. #TeamTomo #PlantScience 🧪🧶🧬🔬🌾
elife.bsky.social
eLife @elife.bsky.social · 18d
🌱 Using ‘compelling’ methods, including #CryoET, researchers mapped spinach thylakoid membranes at single-molecule precision, revealing how photosynthetic complexes are organised and settling long-standing debates on chloroplast architecture.
buff.ly/j3TSIkn
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stcmicrobeblog.bsky.social
STCmicrobeblog @stcmicrobeblog.bsky.social · 17d
cell divisionists & FtsZ fans take note 👇
padaung halsring-schmuck source: https://www.ebay.at/itm/304571100558
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thejoesorg.bsky.social
Joe Sorg @thejoesorg.bsky.social · 26d
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks

jobs.sciencecareers.org/job/675062/f...
Five Tenure-Track Assistant Professor Positions in Microbiology, Evolution, and Biological Clocks - College Station, Texas job with Department of Biology - TAMU | 675062
Texas A&M University (TAMU) invites applications for five full-time, tenure-track Assistant Professor positions
jobs.sciencecareers.org
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archaellum.bsky.social
Sonja-Verena Albers @archaellum.bsky.social · 21d
Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...

Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
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embl.org
EMBL @embl.org · 21d
Are you ready to lead ground-breaking research in Infection Biochemistry?

We are recruiting outstanding scientists to establish research groups based at @cssbhamburg.bsky.social tackling fundamental questions in molecular mechanisms of infection.

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Text box says: "We are hiring".
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jpkbravo.bsky.social
Jack Bravo @jpkbravo.bsky.social · 23d
Join us for the Austrian Cryo-EM Symposium Nov 11–12 at @istaresearch.bsky.social!

Top speakers, cutting-edge cryo-EM, and a chance to explore Vienna & the ISTA campus.

Register now 👉 cryoem-symposium.pages.ist.ac.at #cryoEM #teamtomo
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biology.ox.ac.uk
Oxford Biology @biology.ox.ac.uk · 23d
Oxford Biology is growing 📢

We’re appointing 3 Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology

3 fields. 3 opportunities. One new home for Oxford Biology.

Learn more 👉 bit.ly/41S2Tc7
Apply now 👉 bit.ly/488CNW3
Photo showing the inside atrium of the new Life and Mind Building
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maxplanck.de
Max-Planck-Gesellschaft @maxplanck.de · 23d
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
Graphic with a blue background and light green dots. The text 'call for applications' appears in green, and 'Ausschreibung' in white. A white arrow on the right points diagonally upward.
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