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Ezgi Karaca @ezgikaraca.bsky.social · 7h

🥹😍🥰thank you for this beautiful post!

Debangana Moitra @debanganamoitra.bsky.social · 2d

Just wrapped up the EMBO Integrative Modeling Course, beautifully organized by @ezgikaraca.bsky.social & her amazing team with care🩵! From protein docking & AI-based modeling to endless coffee breaks,seaside dinners, and karaoke, it was science + community at its best. Truly unforgettable @embo.org

Ezgi Karaca @ezgikaraca.bsky.social · 2d

And the legacy continues! 😊

@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿

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Ezgi Karaca @ezgikaraca.bsky.social · 2d

@embo.org

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Ezgi Karaca @ezgikaraca.bsky.social · 2d

And the legacy continues! 😊

@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿

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Reposted by Ezgi Karaca

Marc Lensink @marclensink.bsky.social · 9d

And we're off

The EMBO IntegMod Course has started. All participants received their own mug.

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Ezgi Karaca @ezgikaraca.bsky.social · 10d

Our pleasure, Marc!

Let the #EmboIntegMod25 begin! 🤩

Marc Lensink @marclensink.bsky.social · 11d

Traveling to beautiful Izmir tomorrow for the EMBO meeting on modeling biomolecules interactions, where I will present the CAPRI blind prediction experiment on Tuesday. Looking forward to it. Thanks to @ezgikaraca.bsky.social and other organizers for the invitation

meetings.embo.org/event/25-bio...

Integrative modelling of biomolecular interactions

Experimental structural studies of interactions can be costly, low-throughput, and challenging. Therefore, computational methods aiming to model protein complexes are particularly valuable. The accur…

meetings.embo.org

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Ezgi Karaca @ezgikaraca.bsky.social · 11d

Looking forward hosting you here and listening to your awesome work!! 😍

Matthieu Montes @matthieumontes.bsky.social · 11d

Going to Izmir for the meetings.embo.org/event/25-bio...
I will talk on monday about interactive molecular visualization and simulation methods! See you there!
Thanks to the organizers for the invitation! @ezgikaraca.bsky.social @amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social

Integrative modelling of biomolecular interactions

Experimental structural studies of interactions can be costly, low-throughput, and challenging. Therefore, computational methods aiming to model protein complexes are particularly valuable. The accur…

meetings.embo.org

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Ezgi Karaca @ezgikaraca.bsky.social · Aug 22

Main PhD work, as well as the first first-author paper of @aysebercinb.bsky.social , where we investigate how two nearly identical enzymes target different substrates!!

For more, please 👇

A. Berçin Barlas @aysebercinb.bsky.social · Aug 22

🚀 Excited to share that our article with @ezgikaraca.bsky.social is now published in Communications Biology!

In this study, we explored DNA readout rules of almost identical DNMT3A and DNMT3B (91% sequence similarity!), and we asked: how can nearly the same proteins “see” DNA so differently? 🧬✨

Communications Biology @commsbio.nature.com · Aug 14

Comparative dynamics analysis identifies key residues driving sequence specificity differences between human DNA methyltransferases DNMT3A and DNMT3B.
@aysebercinb.bsky.social‬
@ezgikaraca.bsky.social‬

www.nature.com/articles/s42...

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Ezgi Karaca @ezgikaraca.bsky.social · Jul 29

We just bumped into something very preliminary… but very exciting:

AF2.3 and AF3.0 distograms may potentially reproduce MD-like behavior.

Until we do further tests, you can reach our early insights at www.biorxiv.org/content/10.1...

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Reposted by Ezgi Karaca

Ruben Ragg @rubenragg.bsky.social · Jul 1

Meet the speakers of our anniversary symposium "Advances in Structural Analysis of Biomolecules: From Subcellular Imaging to Drug Design"

cbc-cpc2025.org

October 23-24, 2025, Berlin

Please like and share! #ChemBioPhys2025

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Ezgi Karaca @ezgikaraca.bsky.social · Jun 17

Due to the high level of interest, we have decided to extend the deadline to 10 July.

That means there’s still time to apply for our @embo.org course at meetings.embo.org/event/25-bio... !!

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Ezgi Karaca @ezgikaraca.bsky.social · Jun 11

Speakers: @amjjbonvin.bsky.social @bioinfo.se @brianjimenez @dinaSchneidman @ezgikaraca.bsky.social @lindorfflarsen.bsky.social @matthieumontes.bsky.social @marclensink.bsky.social @oraSchueler-Furman @raphaelGuerois @sokrypton.org @birtheKragelund @alessandraVilla

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Ezgi Karaca @ezgikaraca.bsky.social · Jun 11

Only a few days left to apply for our EMBO course with a great lineup of speakers and tutors! Please feel free to RT!

Course website: meetings.embo.org/event/25-bio...

Organizers: myself, @amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social

Location: www.ibg.edu.tr

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Ezgi Karaca @ezgikaraca.bsky.social · May 13

Also, many thanks to @amjjbonvin.bsky.social & HADDOCK Team for including PROT-ON in their HADDOCK2.4 Antibody-Antigen tutorial!

If you are looking for a real case application example of PROT-ON, you can check: www.bonvinlab.org/education/HA...

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Ezgi Karaca @ezgikaraca.bsky.social · May 13

1 year ago, we launched PROT-ON to help scientists scan and understand mutations across protein-protein interfaces.

Since then, it has been used by researchers from all around the world!

If you haven’t tried PROT-ON yet, here is the link to our web resource: proton.tools.ibg.edu.tr:8001/about

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Ezgi Karaca @ezgikaraca.bsky.social · May 6

Thanks a lot for highlighting our work!! 💚💚

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Reposted by Ezgi Karaca

Centre for Structural Systems Biology CSSB @cssbhamburg.bsky.social · Apr 15

Today is the last day to register for the CSSB Symposium!

www.cssb-hamburg.de/symposium2025

@carobarisch.bsky.social @topf-lab.bsky.social @bosse-lab.bsky.social @landaulabcssb.bsky.social @jankosinski.bsky.social @ezgikaraca.bsky.social @jpoverington.bsky.social @marylynaddo.bsky.social

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Reposted by Ezgi Karaca

Centre for Structural Systems Biology CSSB @cssbhamburg.bsky.social · Mar 31

Ezgi Karaca @ezgikaraca.bsky.social from the Izmir Biomedicine and Genome Center will give a talk during the Emerging Themes session of our symposium.

Register: cssb-hamburg.de/symposium2025

@carobarisch.bsky.social @bosse-lab.bsky.social @landaulabcssb.bsky.social @jankosinski.bsky.social

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Ezgi Karaca @ezgikaraca.bsky.social · Mar 4

🥹🍀🥹🍀

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Reposted by Ezgi Karaca

Stephan Hacker @stephanhacker2.bsky.social · Mar 3

Very much looking forward to the 25th anniversary symposium of ChemBioChem and ChemPhysChem #CBCCPC2025 in Berlin on October 23rd and 24th, 2025.

There is an ever growing list of amazing speakers confirmed for this event. (1/2)

#chemsky #ChemBio @chemistryeurope.bsky.social

www.cbc-cpc2025.org

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Ezgi Karaca @ezgikaraca.bsky.social · Feb 24

I'm so happy to learn that our Turkey-France joint project application with @marclensink.bsky.social has been accepted!

This funding will allow us to explore whether we can sample meaningful protein interaction dynamics with MassiveFold.

Excited to be "officially" collaborating with Marc again! ♥️

TUBITAK 2509 call - France-Turkey bilateral research program

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Ezgi Karaca @ezgikaraca.bsky.social · Feb 22

Inspired by Wallner's AFsample approach, @busrasavas.bsky.social's MinnieFold produced good quality antibody-antigen models even with 95% reduced sampling over CAPRI55 targets.

Just accepted in Proteins!

Paper: www.biorxiv.org/content/10.1...
Github: github.com/CSB-KaracaLa...

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Ezgi Karaca @ezgikaraca.bsky.social · Jan 2

We offer an amazing and timely program, spanning integrative modeling, AI-based protein/complex modeling, and biomolecular dynamics.

There are also several fellowship options!

Looking forward to host this year's fun during 28 September – 03 October 2025 in Izmir 🌴

Ezgi Karaca @ezgikaraca.bsky.social · Jan 2

The legendary EMBO Integrative Modeling Course is back! If you want to be in this picture in the 2025 edition, just go ahead and register at meetings.embo.org/event/25-bio...

Organized by myself & @amjjbonvin.bsky.social & @arneelof.bsky.social & @lindorfflarsen.bsky.social

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Ezgi Karaca @ezgikaraca.bsky.social · Jan 2

The legendary EMBO Integrative Modeling Course is back! If you want to be in this picture in the 2025 edition, just go ahead and register at meetings.embo.org/event/25-bio...

Organized by myself & @amjjbonvin.bsky.social & @arneelof.bsky.social & @lindorfflarsen.bsky.social

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Ezgi Karaca @ezgikaraca.bsky.social · Dec 7

Maybe this one?
Predicting multiple conformations of ligand binding sites in proteins suggests that AlphaFold2 may remember too much
www.pnas.org/doi/abs/10.1...

www.pnas.org

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Ezgi Karaca @ezgikaraca.bsky.social · Dec 7

😍🙌