Fabrizio Menardo
@fmenardo.bsky.social
81 followers 170 following 3 posts
Genomics, evolution and epidemiology of microbial pathogens. University of Zurich.
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Reposted by Fabrizio Menardo
zoebernasconi.bsky.social
Check out our new pre-print! ✨
We cloned AvrWTK4, the first wheat powdery mildew effector recognised by a tandem kinase protein, and show that an HMA-like integrated domain in WTK4 acts as pathogen decoy. Discover the whole story on bioRxiv ⬇️
biorxivpreprint.bsky.social
An HMA-like integrated domain in the wheat tandem kinase WTK4 recognises an RNase-like pathogen effector https://www.biorxiv.org/content/10.1101/2025.08.26.672365v1
Reposted by Fabrizio Menardo
Reposted by Fabrizio Menardo
Reposted by Fabrizio Menardo
biorxiv-evobio.bsky.social
SLiM 5: Eco-evolutionary simulations across multiple chromosomes and full genomes https://www.biorxiv.org/content/10.1101/2025.08.07.669155v1
Reposted by Fabrizio Menardo
reeserichardson.bsky.social
Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community.

reeserichardson.blog/2025/08/04/a...
A do-or-die moment for the scientific enterprise
Reflecting on our paper “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly”
reeserichardson.blog
Reposted by Fabrizio Menardo
wheatpath.bsky.social
"Off-season sex in #Zymoseptoria tritici: little room for late encounters" @biorxivpreprint, sharing our latest study on sexual reproduction in Z. tritici — its epidemiological determinants & impact — may interest those working on plant pathogen dynamics.
doi.org/10.1101/2025...
Reposted by Fabrizio Menardo
mikarantane.bsky.social
Global temperatures would have risen by 12.2 °C (!) since 1990 if everyone in the world had emitted like the wealthiest top 0.1% in world.

Fascinating new study in @natclimate.nature.com by Schöngart et al: www.nature.com/articles/s41...
Bar diagram showing the hypothetical global temperature rise if everyone would have emitted like the given income groups.
Reposted by Fabrizio Menardo
plosbiology.org
Agricultural diseases threaten sustainable food production. @jigisha1.bsky.social @fmenardo.bsky.social & co show that the population structure of #Blumeria #WheatPowderyMildew can be predicted by prevailing wind patterns (& reveal genes under recent selection) @plosbiology.org 🧪 plos.io/43qfH9F
Population structure of wheat powdery mildew in Europe and the Mediterranean. Map shows the geographical distribution of the five populations inferred from fineSTRUCTURE.
Reposted by Fabrizio Menardo
danielcroll.bsky.social
Very excited with @tobybarilbio.bsky.social to share this preprint about his latest work on TEs!

We knew that TEs were very pretty active in this global fungal pathogen of wheat.

Now with nearly 2000 Illumina genomes available, we could finally ask questions about historic TE activation waves.
Reposted by Fabrizio Menardo
ryangutenkunst.bsky.social
The collaborative paper on adding selection to stdpopsim is out! Learn about how to easily simulate realistic population genomic data with background selection and sweeps, plus some benchmarking of methods for demographic history, DFE, and sweep inference. www.biorxiv.org/content/10.1...
Accessible, realistic genome simulation with selection using stdpopsim
Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex de...
www.biorxiv.org