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Frances Arnold @francesarnold.bsky.social · Sep 8

Looking for PhD or postdoctoral opportunities in #AI+biology #proteinengineering? the brilliant @arianemora.bsky.social has joined @aithyra.bsky.social in beautiful #vienna. I wish I could start over again!

AITHYRA Research Institute of the Austrian Academy of Sciences @aithyra.bsky.social · Aug 8

Welcome ARIANE MORA!
With great pleasure we announce that Ariane Mora is one of the Starting Principal Investigators AI/LS who will join AITHYRA in November 2025. Ariane combines molecular biology, AI, and software engineering. More information: www.oeaw.ac.at/aithyra/rese...
#AITHYRA #StartingPI

Ariane Mora = impact-driven + climber + Australian + open-source enthusiast + collaborative

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Frances Arnold @francesarnold.bsky.social · Sep 4

Our new paper on AI-generated TrpBs with @anima-anandkumar.bsky.social. GenSLM generated very useful promiscuous TrpB #enzymes, bypassing a lot of #directedevolution! great work by the whole team, especially Theophile Lambert. www.biorxiv.org/content/10.1...

www.biorxiv.org

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Reposted by Frances Arnold

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · Sep 3

A compelling review of how ML/AI could help in the quest to find an enzyme for every reaction.

@jsunn-y.bsky.social @francescazfl.bsky.social Yueming Long @francesarnold.bsky.social

www.cell.com/cell-systems...

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Frances Arnold @francesarnold.bsky.social · Sep 3

Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.

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Frances Arnold @francesarnold.bsky.social · Aug 10

On the beautiful @Caltech campus with two new professors @reisenbauerlab.bsky.social and @arianemora.bsky.social headed to start their careers in Vienna. Prospective graduate students take note! This is the future of #enzymes #proteinengineering. @caltechcce.bsky.social @caltech.edu

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Frances Arnold @francesarnold.bsky.social · Jul 31

Loved seeing so many former #Arnoldgroup members at GRC #ProteinEngineering this week! Protein engineering is in good hands.

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Frances Arnold @francesarnold.bsky.social · Jul 22

I'm really proud of this work by Jae Kennemur and Yueming Long. #Enzymes rock, with some help from #directed evolution to do chemistry not known in nature (and really hard for humans, too). @caltechcce.bsky.social
pubs.acs.org/doi/10.1021/...

Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes

Azaspiro[2.y]alkanes are increasingly valuable scaffolds in pharmaceutical drug discovery; however, an asymmetric catalytic method for their synthesis remains unknown. Here, we present a stereodiverge...

pubs.acs.org

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Frances Arnold @francesarnold.bsky.social · Jul 12

I saw it firsthand at the Lindau Nobel Laureates meeting--international young scientists welcomed and recruited in Germany and elsewhere.
www.wsj.com/politics/pol...

America’s Brain Drain Could Become the World’s Brain Gain

Research-funding cuts and immigration changes threaten some of America’s economic advantages.

www.wsj.com

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Reposted by Frances Arnold

imbb-forth.bsky.social @imbb-forth.bsky.social · Jul 2

📅July 7-11
The 2025 Onassis Lectures in Biology and Chemistry will be held @forth-ite.bsky.social, Heraklion, Crete. This year’s Lectures are devoted to the advances, challenges, and future prospects of #Re-engineeringBiology through #DirectedEvolution and #Synthetic cellular pathways.

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Reposted by Frances Arnold

Stephan Hammer @stephanhammer.bsky.social · Jun 27

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry.
🙏 RETWEET (We want to recruit internationally)

Organic chemistry meets #DirectedEvolution
Highly interdisciplinary & passionate research group

uni-bielefeld.hr4you.org/job/view/433...

Research Position (PhD) in organic chemistry and b...

<div style="text-align: justify;">The  research  group  „Organic  Chemistry  and&nb...

uni-bielefeld.hr4you.org

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Frances Arnold @francesarnold.bsky.social · Jun 27

Really enjoying #Repartzymes Repurposed and Artificial Enzymes meeting organized by #TomWard of Uni. Basel. Many former group members are here! rep.artzymes.info

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Frances Arnold @francesarnold.bsky.social · Jun 25

I'm honored to be involved in the SDSS @stanforddoerr.bsky.social --we need it now more than ever. Let's continue to be bold about building the future.

Stanford Doerr School of Sustainability @stanforddoerr.bsky.social · Jun 25

Join us in welcoming @francesarnold.bsky.social to the @stanforddoerr.bsky.social Advisory Council. As the @caltech.edu Linus Pauling Professor and a Nobel Laureate in Chemistry, she will make important contributions to the school’s bold ambition of building a more sustainable future for all.

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Reposted by Frances Arnold

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · May 22

Steered generation for protein optimization: On datasets with ~10^2 measurements, steering a discrete diffusion model outperforms RL on a protein language model for generating improved variants.

@jsunn-y.bsky.social @francesarnold.bsky.social @yisongyue.bsky.social

arxiv.org/abs/2505.15093

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Frances Arnold @francesarnold.bsky.social · Mar 30

Took a walk in the woods this weekend. So good for the soul.

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Frances Arnold @francesarnold.bsky.social · Mar 27

Such a pleasure to gather with current and former Arnold group members in San Diego! Thank you one and all. #ACSSpring2025

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Frances Arnold @francesarnold.bsky.social · Mar 25

My @acs.org Priestley award address can be found here
fhalab.caltech.edu/wp-content/u...

fhalab.caltech.edu

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Frances Arnold @francesarnold.bsky.social · Mar 25

I got to tell some stories I don't usually include in science talks. Thank you for coming. I will post the address on my website soon.

gsbardella.bsky.social @gsbardella.bsky.social · Mar 24

An amazing, totally inspirational and emotional journey! The @acs.org Priestley Medal talk by @francesarnold.bsky.social at #ACSSpring2025

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Frances Arnold @francesarnold.bsky.social · Mar 23

Thank you for visiting! We loved hearing about protein evolution--nature is very creative--you are helping us understand how novelty arises.

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Reposted by Frances Arnold

Bethany Halford @bethanyhalford.bsky.social · Mar 21

Before you meet @francesarnold.bsky.social at #ACSSpring2025, read my profile of her in @cenmag.bsky.social

cen.acs.org/people/award...

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Reposted by Frances Arnold

C&EN (Chemical & Engineering News) @cenmag.bsky.social · Mar 13

Meet @francesarnold.bsky.social, 2025 Priestley Medalist, at #ACSSpring2025.

Stop by the ACS Booth Theater in the Expo Hall to hear about her contributions to #chemistry and pick up a signed copy of her C&EN feature issue.

RSVP: connect.discoveracs.org/cen-priestle... #chemsky

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Reposted by Frances Arnold

Will Thomas @williamthomas.bsky.social · Jan 20

Also remember that the National Archives maintains prior administrations' websites, e.g., bidenwhitehouse.archives.gov. I spent a lot of time unnecessarily downloading the Obama-era OSTP archive in 2017.

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Frances Arnold @francesarnold.bsky.social · Jan 20

The White House website has been wiped clean, but thanks to @erichorvitz.bsky.social , all the Biden #PCAST reports are available below. I want to thank the #PCAST members, all of whom donated their time and expertise to helping policy be science-based. tinyurl.com/2acnv2nh

PCAST Reports (2020-2025)

tinyurl.com

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Reposted by Frances Arnold

Jason Yang @jsunn-y.bsky.social · Jan 16

Happy to share that our work on Active Learning-Assisted Directed Evolution is now published in @naturecomms.bsky.social!

Paper: www.nature.com/articles/s41...

Check out the original thread here: x.com/jsunn_y/stat...

x.com

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Frances Arnold @francesarnold.bsky.social · Jan 12

Hell continues in #LosAngeles with the #LAfires. I live next to #Altadena, which is pretty much destroyed. My power finally came on after three cold nights. So many have lost their homes, and danger not over since big winds are coming back starting tomorrow. Views at my house Wednesday early am.

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Frances Arnold @francesarnold.bsky.social · Jan 9

#eatonfire near me. So many have lost their homes. Power is out and I am drinking the best wine.

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