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Reposted by Frank Schnorrer

FlyBase @flybase.bsky.social · 5d

There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila

FlyBase Update – October 2025
The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support:
• European labs: Please consider contributing to the Cambridge, U.K. FlyBase group
• U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups
• Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience.
For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

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Reposted by Frank Schnorrer

Felix Rico @felixrico.bsky.social · Sep 2

We close the day at #25EngLife with an inspiring talk by @frankschnorrer.bsky.social Titin rules!

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Frank Schnorrer @frankschnorrer.bsky.social · Aug 29

Read about how female muscles grow larger than male ones! and hearts too!

soumitrakp.bsky.social @soumitrakp.bsky.social · Aug 27

Excited to share our new preprint on bioRxiv: "Cell type specific allometry controls sex-differences in Drosophila body size"!

www.biorxiv.org/content/10.1...

Cell type specific allometry controls sex-differences in Drosophila body size

Species and sex-specific differences in organ size are fundamental features of animal biology, yet the mechanisms that drive these differences remain debated. Adult female Drosophila are larger than m...

www.biorxiv.org

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Frank Schnorrer @frankschnorrer.bsky.social · Aug 29

Females are larger than males. How? Here is one solution- they have MORE nuclei in their flight muscles and grow LARGER heart and fat body cells with MORE ribosomal mRNAs. Fun collaboration of @jeromeavellaneda.bsky.social with @soumitrakp.bsky.social & Brian Oliver www.biorxiv.org/content/10.1...

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Frank Schnorrer @frankschnorrer.bsky.social · Jul 26

Thanks Laurent!

Frank Schnorrer @frankschnorrer.bsky.social · Jul 21

Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

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Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

Thanks so much Brian 😀

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Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

Thanks Ale 😊

Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

Thanks Julien

Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

Thanks so much. Brian, very glad to hear that this is likely conserved. We tried to a bit in mouse but are not experts and could get convincing data in 3D.

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Frank Schnorrer @frankschnorrer.bsky.social · Jul 10

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

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Reposted by Frank Schnorrer

Biomedical Picture of the Day BPoD @bpodaily.bsky.social · May 14

Visualising where different genes are switched on throughout a fly

📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social

➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers

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Frank Schnorrer @frankschnorrer.bsky.social · May 12

Thanks Ken

Reposted by Frank Schnorrer

NordenLab @nordenlab.bsky.social · May 10

The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....

Timely neurogenesis drives the transition from nematic to crystalline nuclear packing during retinal morphogenesis

You have to enable JavaScript in your browser's settings in order to use the eReader.

www.science.org

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Frank Schnorrer @frankschnorrer.bsky.social · May 10

I see 😊 so nice to be together there - and nematic to crystalline applies to sarcomerogenesis too. 💡💡. Congrats Caren

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Frank Schnorrer @frankschnorrer.bsky.social · May 10

Thanks Francoise

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Frank Schnorrer @frankschnorrer.bsky.social · May 10

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social
www.science.org/doi/epdf/10....

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Frank Schnorrer @frankschnorrer.bsky.social · Apr 6

😀 looking forward to continuing our collaboration

Benjamin Friedrich @friedrich-group.bsky.social · Apr 6

Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social

More information here:
physics-of-life.tu-dresden.de/friedrich

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Frank Schnorrer @frankschnorrer.bsky.social · Mar 25

Congrats Stefan, very cool news 😀

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Reposted by Frank Schnorrer

Stefan Luschnig @luschnig.bsky.social · Mar 24

Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de

Epithelial biology: Holding the corners together

A new study reveals that the Drosophila follicular epithelium opens its permeability barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open, cell vertices. This work res...

www.cell.com

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Frank Schnorrer @frankschnorrer.bsky.social · Mar 18

Fly group leaders in Eastern Europe, UK, France, Germany, Switzerland/Austria, please step forward. The European Fly community needs your help. #Drosophila #EDRC

European Drosophila Society @fly-eds.bsky.social · Mar 18

European Drosophila Board election call for nominations. Join the EDB to represent and support Drosophila research in Europe! Five representatives will be elected for different regions. Check our election page for details:
europeandrosophilasociety.org/european-dro...
#Drosophila, #EDRC2025

A fly voting in the European Drosophila Board election

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Reposted by Frank Schnorrer

François Leulier @francoisleulier.bsky.social · Mar 6

💪🇺🇸🇫🇷

Stand Up For Science France @standupforscifr.bsky.social · Mar 4

Press release from Stand Up For Science France (cc @standupforscience.bsky.social)

Standing Up For Science in France
In the face of Trump’s administration’s relentless attacks on democratic institutions,
civil rights, science, public health agencies, environmental regulation, and climate
data collection, and as universities and research institutions across Europe also come
under increasing pressure, the French scientific community is taking action. On March 7,
2025, scientists, educators, students, and concerned citizens will march and rally in cities
across France to defend science and the humanities as pillars of democracy.
This mobilization is organized in solidarity with the "Stand Up For Science" movement in the US.

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Frank Schnorrer @frankschnorrer.bsky.social · Mar 6

Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org
elifesciences.org/reviewed-pre...

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Frank Schnorrer @frankschnorrer.bsky.social · Mar 4

Welcome PAvel - so nice to see you there 🌞

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Frank Schnorrer @frankschnorrer.bsky.social · Feb 4

@biancah0406.bsky.social

CNRS @cnrs.fr · Feb 4

#PodcastCNRS 🎧 Quels mécanismes sont impliqués dans la fonte musculaire lors d’une maladie ou en vieillissant ? Bianca Habermann, tente de répondre en observant les mitochondries, siège de la fabrication de notre énergie !

👉 smartlink.ausha.co/cnrs-qu-est-...

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