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Reposted by Benjamin Friedrich

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Aug 3

Why do secondary #tumors go for #MET during the metastatic cascade? Our new study suggests that immune evasion—rather than faster proliferation—might give them the edge.
👉 cell.com/iscience/ful...
#CancerResearch #TumorBiology #Immunology #Metastasis

Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids

Microenvironment; Biological process; Cancer

cell.com

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Reposted by Benjamin Friedrich

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Aug 3

How do individual proteins sculpt the epithelial basement membrane?
Our new study uncovers their role in network structure, nematic alignment & fractal patterns.
🔗 www.sciencedirect.com/science/arti...
#CellBiology #ECM #BasementMembrane

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Reposted by Benjamin Friedrich

Becker Group at CRTD @beckergroup.bsky.social · Jul 9

Fabulous job call @tudresden.bsky.social @cmcb-tud.bsky.social @dcgenomecenter.bsky.social is looking for a new head. Post is for two years in the first instance, remunerated at group leader level with lots of opportunity to drive development and science
www.verw.tu-dresden.de/StellAus/ste...

Vacancy ID 12257

www.verw.tu-dresden.de

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Benjamin Friedrich @friedrich-group.bsky.social · Jul 10

Sarcomeres are the contractile units of muscle 💪. During development, sarcomeres divide to add new sarcomeres - out now and on the cover. Great work by @clementrodier.bsky.social Ian Estabrook @frankschnorrer.bsky.social at @ibdm.bsky.social & @poldresden.bsky.social: doi.org/10.1126/scia...

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Reposted by Benjamin Friedrich

Physics of Life Dresden @poldresden.bsky.social · Jul 10

🎉Paper alert!

Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social and collaborators for their new findings (+cover!) published in Science Advances. They reveal a novel mechanism for muscle growth via division of sarcomeres, throughout myofibrils

Learn more: tud.link/35mkgk

Sarcomere Division: A New Mechanism of Muscle Growth Under Tension

Researchers from the Friedrich group at PoL have identified a novel sarcomere division mechanism, explaining how muscles add new contractile units under high mechanical stress.

tud.link

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Benjamin Friedrich @friedrich-group.bsky.social · Jul 10

Wonderful theory-experiment collaboration with @frankschnorrer.bsky.social on muscle growth: by detecting and analyzing thousands of sarcomeres, we discovered a mechanism of tension-driven sarcomere addition: a mother sarcomeres divide daughter sarcomeres - now out: www.science.org/doi/10.1126/...

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Reposted by Benjamin Friedrich

TU Dresden @tudresden.bsky.social · May 22

Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...

Picture of the PIs of TUD's Clusters of Excellence and Cluster of Excellence Initiatives beeing happy.

Picture of TUD's Rector Prof. Ursula Staudinger during the announcement of the funding decision of the DFG.

Picture of cheering guests in the ballroom of the Rectorate Building.

Picture of TUD's Rector Prof. Ursula Staudinger and cheering guests in the ballroom of the Rectorate Building.

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Reposted by Benjamin Friedrich

Deutsche Forschungsgemeinschaft @dfg.de · May 22

The #ClustersOfExcellence have been selected: today, the Excellence Commission approved 70 projects for funding. 45 clusters will continue and 25 will be newly established. Funding starts on 1 Jan 2026 for 7 years, with €539 million per year. The full list: www.dfg.de/resource/blo... 1/3

Map of Germany with the Clusters of Excellence

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Reposted by Benjamin Friedrich

TUD | Center for Molecular and Cellular Bioengineering (CMCB) @cmcb-tud.bsky.social · Apr 22

Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!

✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.

Apply now ➡️ tud.link/vejrmx

#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology

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Reposted by Benjamin Friedrich

Physics of Life Dresden @poldresden.bsky.social · May 21

One week left to apply to the Physics of Life MSc this year! Students learn first-class research skills and can also avail of #scholarships to aid their studies.

Learn more and apply: physics-of-life.tu-dresden.de/career-educa...

#internationalstudents #MSc #EnglishMSc #Physics #studyabroad

TUD | Center for Molecular and Cellular Bioengineering (CMCB) @cmcb-tud.bsky.social · Apr 22

Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!

✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.

Apply now ➡️ tud.link/vejrmx

#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology

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Reposted by Benjamin Friedrich

Leo Otsuki @leootsuki.bsky.social · May 21

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14

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Reposted by Benjamin Friedrich

Deutsche Forschungsgemeinschaft @dfg.de · May 22

Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3

Deutschlandkarte der Verteilung der Exzellenzcluster auf Bundesländer und Universitäten.

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Benjamin Friedrich @friedrich-group.bsky.social · Apr 6

Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social

More information here:
physics-of-life.tu-dresden.de/friedrich

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Benjamin Friedrich @friedrich-group.bsky.social · Apr 4

It was wonderful to meet you at our #cilia meeting - thank you for your great talk!

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Reposted by Benjamin Friedrich

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Mar 9

🚀 Looking for an #HFSP ally? We’ve got you covered with #AtomicForceMicroscopy, #CellCulture, #Mechanobiological #Modeling, & more! 🤝 Interested? Let’s connect! 📧 Details 👉 physics-of-life.tu-dresden.de #Collaboration

PoL – Physics of Life | Team | PoL Groups | Elisabeth Fischer-Friedrich

Physics of Life: Discover new paradigms for understanding life and deepen our knowledge of living biological matter

physics-of-life.tu-dresden.de

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Reposted by Benjamin Friedrich

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Mar 27

It’s the #filopodia, stupid! 🚀
We just released our new study uncovering how filopodia and hydrostatic #pressure contribute to the regulation of #membrane #tension.
👉 Check it out on bioRxiv: biorxiv.org/content/10.1...
#cellbiology #biophysics #actin #mechanobiology

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Reposted by Benjamin Friedrich

Physics of Life Dresden @poldresden.bsky.social · Mar 4

A fantastic collaboration between PoL members @stefandiezlab.bsky.social and @friedrich-group.bsky.social published now in @naturephysics.bsky.social - well done to all involved! 🎉🤓

Check out the official CMCB press release below:

TUD | B CUBE - Center for Molecular Bioengineering @bcube-tud.bsky.social · Mar 4

⁉️ How can cilia beat rhythmically?

The Diez Lab @stefandiezlab.bsky.social and @friedrich-group.bsky.social at @poldresden.bsky.social found a twisting motion during cilia beats that might play a key role in coordinating their tiny molecular motors! 🌀⚙️

Read more ➡️ tud.link/wr8ze9

#CMCBnews

Verborgene Verdrillung: Forschende enthüllen die geheime Bewegung von Zilien

Spermien bewegen sich fort, indem sie ihre Geißel rhythmisch schlagen. Ähnliche Geißeln, bekannt als Zilien, finden sich auch in Zellen der Lunge und des Gehirns, wo sie Flüssigkeit durch das Gewebe …

tud.link

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Reposted by Benjamin Friedrich

natalieadye.bsky.social @natalieadye.bsky.social · Feb 18

I'm looking for a talented+motivated person to join my team at the #MechanobiologyInstitute @NUS for a #postdoc. If you're interested in investigating collective cell behavior during 3D tissue #morphogenesis with me, please apply here or PM for Qs. Please RT! careers.nus.edu.sg/job/Research...

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Reposted by Benjamin Friedrich

Gaspar Jekely @jekely.biologists.social.ap.brid.gy · Feb 7

New preprint from the lab on #coral larval light responses, including ciliary arrests and body-wide contractions.

Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social

#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1

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Benjamin Friedrich @friedrich-group.bsky.social · Feb 18

Preprint: How do axolotl regrow lost limbs that match the size of the organism? A model of coupled morphogen dynamics & tissue growth suggests that some morphogen parameters should scale with animal size, but stay constant during regeneration, i.e. show static scaling www.biorxiv.org/content/10.1...

Axolotl salamanders can regrow lost limbs that match the variable size of the adult organism. This example of adaptive morphogenesis inspired us to formulate a minimal model of coupled morphogen dynamics and tissue growth. In our preprint, we show that this simple feedback ensures robust growth arrest and proportional growth, provided at least some morphogen gradient parameters scale proportionally to animal size, but then stay constant during regeneration. We compare theory prediction and experimental quantification of SHH and FGF morphogen parameters in regenerating blastema of animals of different size and at different time points of regeneration, revealing static scaling of the FGF source size, which is sufficient to ensure proportional growth in our model.

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Reposted by Benjamin Friedrich

Physics of Life Dresden @poldresden.bsky.social · Feb 7

Fantastic work done by PoL PI @fischerfriedriclab.bsky.social with the Dahmann lab, published in Development @dev-journal.bsky.social earlier this month.

Well done to all involved in this collaboration!

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Feb 4

It turns out that #EggChamber #elongation and rotation can be decoupled in #Drosophila egg chamber #morphogenesis - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/... . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳

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Reposted by Benjamin Friedrich

Journal of Cell Science @jcellsci.bsky.social · Feb 6

We invite you to submit your latest research to our special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social.
journals.biologists.com/jcs/pages/ci...

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Reposted by Benjamin Friedrich

Fischer-Friedrich Lab @fischerfriedriclab.bsky.social · Feb 4

It turns out that #EggChamber #elongation and rotation can be decoupled in #Drosophila egg chamber #morphogenesis - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/... . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳

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Reposted by Benjamin Friedrich

Mattia Serra @mattiaserra.bsky.social · Jan 16

📣 Excited to receive the 💥 NSF CAREER 💥 Award. Our group is looking for PhD students and postdocs interested in the Nonlinear Dynamics and the Physics of Living Systems, with support from NSF, HFSP, and other sources. We’d appreciate your help in spreading the word! @ucsdphysci.bsky.social

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Benjamin Friedrich @friedrich-group.bsky.social · Jan 14

4 places left! Workshop "Biophysics of Motile Cilia": Topics: #axoneme mechanics, #synchronization, #navigation, #ciliopathies, ... Meet us in Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltun...

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