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Giusy Mariano @giusym1990.bsky.social · 7d

🚨PhD Opportunity Alert🚨 Join me, @suzieh.bsky.social and @walllabuoglasgow.bsky.social to investigate how environment shapes anti-phage defences & prophage–prophage conflict in Pseudomonas aeruginosa.
Apply here:
www.gla.ac.uk/postgraduate...

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Reposted by Giusy Mariano

Sazanov Lab @sazanovlab.bsky.social · 20d

How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint!
t.co/962Kj9pt6F

https://www.biorxiv.org/content/10.1101/2025.09.16.676506v1

t.co

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Reposted by Giusy Mariano

Stephen Garrett @stephenrgarrett.bsky.social · 22d

Really excited to share my first paper from the Whitney lab, alongside an amazing grad student, Polina. Here we identify a chaperone family required for the folding of a central domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. www.pnas.org/doi/10.1073/...

A widespread family of molecular chaperones promotes the intracellular stability of type VIIb secretion system–exported toxins | PNAS

To survive in highly competitive environments, bacteria use specialized secretion systems to deliver antibacterial toxins into neighboring cells, t...

www.pnas.org

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Giusy Mariano @giusym1990.bsky.social · May 9

It was a really nice experience to give a talk at Northumbria University! Very happy to get to present our work on Zorya systems for the first time - A huge thank you to @emmseveri.bsky.social and (not on bluesky?) Ciarán Kelly and Darren Smith for the invitation!

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Reposted by Giusy Mariano

Stephen Garrett @stephenrgarrett.bsky.social · Apr 14

Really excited to share this story from Jake in the lab! We have found bacterial protein toxins that can enter Gram positive bacterial cells without the need for a receptor resulting in broad spectrum antibacterial activity.

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Apr 14

Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria https://www.biorxiv.org/content/10.1101/2025.04.13.648598v1

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Giusy Mariano @giusym1990.bsky.social · Apr 4

For those of you who approached me at @microbiologysociety.org #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Reposted by Giusy Mariano

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Reposted by Giusy Mariano

Aleksei Agapov @alekseiagapov.bsky.social · Mar 31

Presenting a poster at #Microbio25 today/tomorrow. Come for a chat about defence hotspots in Pseudomonas phage!

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Giusy Mariano @giusym1990.bsky.social · Mar 17

Still time left to apply!!

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Giusy Mariano @giusym1990.bsky.social · Mar 9

Pleased to share that my main Sir Henry Wellcome Fellowship project is now published! This study provides mechanistic insights into Zorya II function. Grateful to all who contributed! Read it here:https://tinyurl.com/ZoryaII

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Giusy Mariano @giusym1990.bsky.social · Feb 26

We have extended the deadline for this! If you are passionate about phage-bacteria interactions, check this out and join us!

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Reposted by Giusy Mariano

Suzie Humphrey @suzieh.bsky.social · Feb 8

🚨 #PhD opportunity! 🚨

Come and work with @evaheinz7.bsky.social and me at the University of Strathclyde (Glasgow) on an exciting project investigating the roles that #bacteriophages play in the evolution and virulence of #enterococci. 🧫🧬

Details here: www.strath.ac.uk/studywithus/...

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Reposted by Giusy Mariano

University of Glasgow School of Infection & Immunity @uofgsii.bsky.social · Feb 21

📌 WE ARE HIRING!

@uofgsii.bsky.social is seeking to appoint a Research Associate in Molecular Microbiology.

⏺️ Vacancy Ref: 164773
⌛️ Closing date: 24 Feb 2025
📧 Informal Enquiries: Dr @giusym1990.bsky.social [email protected]

More Info | How To Apply: www.jobs.gla.ac.uk/job/research...

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Giusy Mariano @giusym1990.bsky.social · Feb 18

Still time to apply! Join us in Glasgow—be part of my team. Closing date: Feb 24th

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Giusy Mariano @giusym1990.bsky.social · Feb 10

Love phage-bacteria interactions, anti-phage systems, and a sprinkle of evolutionary biology? There’s still time to apply and join our team in Glasgow at @uofgsii.bsky.social !

Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Reposted by Giusy Mariano

Rémi Fronzes @fronzeslab.bsky.social · Jan 26

We are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis.
#CryoEM #microsky

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Giusy Mariano @giusym1990.bsky.social · Jan 24

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

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Giusy Mariano @giusym1990.bsky.social · Dec 16

Happy to share the final version of our paper on Serratia defence islands. Congrats to first-authors Tom and Suraj, and a big thank you to Blowerlab and @stephenrgarrett.bsky.social tinyurl.com/3vnyvufa

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Giusy Mariano @giusym1990.bsky.social · Dec 11

Thank you!

Giusy Mariano @giusym1990.bsky.social · Dec 11

Massive thanks to everyone who helped and supported me during the preparation—half of whom I can't tag because they’re not on BlueSky! 😅

Giusy Mariano @giusym1990.bsky.social · Dec 11

Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow !! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!

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Giusy Mariano @giusym1990.bsky.social · Nov 29

That is totally the first thing i thought when i chose the new job! 😆

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Giusy Mariano @giusym1990.bsky.social · Nov 29

"Now that shipments are booked and the flat is moved, it’s official… Starting from January, I’m thrilled to announce that my lab is moving to the University of Glasgow! 🎉 More good news will follow soon—once I’m free to share them! Very happy to return to Scotland 🧪✨

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Reposted by Giusy Mariano

Sorek Lab @soreklab.bsky.social · Dec 19

News on the Zorya defense system: anchors to the peptidoglycan and detects membrane disruption by phage. It has a flagella-motor-like device that rotates once activated. So cool! I've been waiting for insights on Zorya since we first described it 5 years ago. Congrats Tylor&co!

t.co/WFvS9FePB5

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Reposted by Giusy Mariano

Justine Rudkin @scousemicrobe.bsky.social · Dec 11

Come do a PhD with me at University of Glasgow.
3-year fully funded PhD for UK students.
Friend to Foe: Colonisation as an Entry Point for S. aureus Infectionhttps://www.findaphd.com/phds/project/fully-funded-friend-to-foe-colonisation-as-an-entry-point-for-staphylococcus-aureus-infection/?p166823

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