Lightnews — Scholar-powered news

Goran Bajic @gogo-science.bsky.social · 10h

Amazing! Congratulations! 👏🏻👏🏻👏🏻

1 1

Goran Bajic @gogo-science.bsky.social · 2d

I did not expect Treg!

Goran Bajic @gogo-science.bsky.social · 4d

My guess is Mojsov et al. 🤗

1 3

Reposted by Goran Bajic

Magnus Bauer @kinasekid.bsky.social · 8d

Phosphorylation on tyrosines control key pathways in immunity, cancer, and metabolism. For the first time, we can now design proteins that specifically recognize individual phosphotyrosines, even in disordered regions. (1/8)

Preprint: www.biorxiv.org/content/10.1...

1 18 44

Goran Bajic @gogo-science.bsky.social · 15d

Congrats!

1

Reposted by Goran Bajic

Current Biology @currentbiology.bsky.social · Aug 28

Feeling mitochondrially challenged lately?

Here are two classic reviews on #mitochondria that should help.

www.cell.com/current-biol...

www.cell.com/current-biol...

The Origin and Diversification of Mitochondria

Moving beyond the simplistic view of mitochondria as the power house of the cell, Roger et al. present the immense diversity of mitochondria and mitochondrial functions across eukaryotes, and bring th...

www.cell.com

3 44 120

Reposted by Goran Bajic

Seth Thomas Scanlon @immunoeditor.bsky.social · Aug 29

Heads up: @science.org is looking for a new research #editor based in the US or UK to handle papers in #InfectiousDiseases (e.g., #virology, #microbiology, #parasitology) & #microbiome research! This is an amazing opportunity, so don't delay! Applications are due 22 SEP!

recruiting.ultipro.com

5 3

Goran Bajic @gogo-science.bsky.social · Aug 27

Congrats!

Goran Bajic @gogo-science.bsky.social · Aug 26

New paper from the Coelho lab with a modest contribution from us:

Camila Coelho, PhD MBA @camilahcoelho.bsky.social · Aug 26

🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published:
👉 www.cell.com/cell/fulltex...
[1/9]

Human monoclonal antibodies targeting A35 protect from death caused by mpox

Three potent mAbs against the conserved MPXV A35 protein block viral spread, protect against lethal infection in mice, and align with protective antibody responses in convalescent humans, establishing...

www.cell.com

1 3

Goran Bajic @gogo-science.bsky.social · Aug 15

@cryoempapers.bsky.social

Reposted by Goran Bajic

Camila Coelho, PhD MBA @camilahcoelho.bsky.social · Aug 12

🚨 New Publication!!!

I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]

Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...

www.cell.com

3 14 40

Goran Bajic @gogo-science.bsky.social · Aug 12

The latest from us:
www.cell.com/cell-reports...
With Camila Coelho’s lab, we describe how public clonotype #antibody affinity matures against an occluded epitope on #spike we call the central interface epitope! #cryoEM

Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...

www.cell.com

1 2

Reposted by Goran Bajic

cryoEM papers @cryoempapers.bsky.social · Jul 27

Mix-it-up: Accessible time-resolved cryo-EM on the millisecond timescale www.biorxiv.org/content/10.1101/2025.07.22.666177v1 #cryoem

5 6

Reposted by Goran Bajic

Seth Thomas Scanlon @immunoeditor.bsky.social · Jun 25

To celebrate @focisimmunology.bsky.social 's annual meeting this week, #Science #Immunology has just released a new free sample collection of recent papers with a focus on human immunology! The collection will be available online to read until the end of July 2025! #FOCIS2025

bit.ly/SciImm_free

1 4 15

Goran Bajic @gogo-science.bsky.social · Jun 18

So cool!

1

Goran Bajic @gogo-science.bsky.social · May 31

#cryoEM #antibody

Goran Bajic @gogo-science.bsky.social · May 31

Another fruitful collaboration with the Coelho lab!

www.sciencedirect.com/science/arti...

1 2

Goran Bajic @gogo-science.bsky.social · Apr 23

Latest from us: another productive collaboration with the Schmidt lab on #flu #antibody

www.science.org/doi/10.1126/...

Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies

Broadly reactive human antibodies recognizing the head and stem of influenza hemagglutinin.

www.science.org

1 5

Goran Bajic @gogo-science.bsky.social · Apr 9

Can’t wait to try this new feature out!

Structura Biotechnology @structurabio.bsky.social · Apr 9

#CryoSPARC v4.7 is out! 🚀
Featuring a new automatic Micrograph Junk Detector that labels and rejects contaminants, new tools for curating subsets of particles, performance and stability fixes, and more!
Full changelog: cryosparc.com/updates

#cryoEM

Goran Bajic @gogo-science.bsky.social · Mar 11

All props to our students, Vishal and Iden, who spearheaded this study!

Vishal Rao @vishalnrao.bsky.social · Mar 11

Glad to share our work from @camilahcoelho.bsky.social’s lab on identifying affinity-enhancing somatic hypermutations in public antibodies based on convergence and clonotype-enrichment!

www.biorxiv.org/content/10.1...

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody

Public antibodies that recognize conserved epitopes are critical for vaccine development, and identifying somatic hypermutations (SHMs) that enhance antigen affinity in these public responses is key t...

www.biorxiv.org

2

Goran Bajic @gogo-science.bsky.social · Feb 26

Thanks for sharing. Aaron and I are really proud of this paper.

1

Goran Bajic @gogo-science.bsky.social · Feb 7

Really disappointed with #HHMI
www.science.org/content/arti...

HHMI kills program aimed at boosting inclusivity in STEM education

“Inclusive excellence” program had committed $60 million to 104 institutions

www.science.org

5

Goran Bajic @gogo-science.bsky.social · Jan 28

Thanks for the shoutout 🙏🏻

1

Goran Bajic @gogo-science.bsky.social · Jan 24

Our long-awaited study in collaboration with the Schmidt lab on H5Nx influenza recognition by naive B cells is out! #antibody #bcell #flu #avianflu #cryoEM

www.science.org/doi/10.1126/...

Human naïve B cells recognize prepandemic influenza virus hemagglutinins

Antibodies targeting the influenza hemagglutinin from potentially pandemic H5Nx viruses can be isolated from naïve individuals.

www.science.org

13 33

Goran Bajic @gogo-science.bsky.social · Jan 24

Thanks for sharing! 😀