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grocottlab.bsky.social
Grocott Lab
@grocottlab.bsky.social
1.8K followers 2K following 16 posts
Dr Tim Grocott's research group, University of East Anglia UK. 🐣 embryology & new adventures in human development via stem cells. Modelling in silico/vitro. Fascinated by signalling networks, patterning, all things early development and the eye.
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grocottlab.bsky.social
Grocott Lab @grocottlab.bsky.social · Mar 6
Need to electroporate and/or live image avian embryos? We hope our new preprint will help you get started:

www.biorxiv.org/content/10.1...

Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo

🧪🐣 #devbio
A still image of a stage HH4 gastrulating chick embryo electroporated with 3 different fluorescent reporter genes shown in magenta, yellow and cyan.
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Reposted by Grocott Lab
catsbearsandme.bsky.social
Charlotte the Procrastinator @catsbearsandme.bsky.social · 10h
#WildWomanSisterhood
They asked: "Why is it important to be kind?" I said: Because we walk past hundreds of people every day, and none of them wear signs that say, "I'm grieving," "I'm exhausted", or "I'm barely holding it together."
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johninnescentre.bsky.social
John Innes Centre @johninnescentre.bsky.social · 8h
Applications are now OPEN for the JIF Rotation PhD Programme

This prestigious 4-year #PhD programme trains graduate students in Plant and Microbial Sciences at the JIC, @thesainsburylab.bsky.social and @earlhaminst.bsky.social.

🗓️ Closing date - 13 November 2025

www.jic.ac.uk/training-car...
Rotation biology PhDs | John Innes Centre
Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…
www.jic.ac.uk
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natclarke.bsky.social
Nat Clarke @natclarke.bsky.social · 9h
🚨 My lab is hiring at all levels!

Interested in animal origins & evolutionary cell biology?

I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.

🔗: clarkelab.com/join/

Please repost!
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mangieserrano.bsky.social
Angie Serrano @mangieserrano.bsky.social · 10h
So, when you’re changing media in your iPSCs today, take a moment to be amazed by what frogs taught humans. 🐸

You can read the article here journals.biologists.com/dev/article/...
The Developmental Capacity of Nuclei taken from Intestinal Epithelium Cells of Feeding Tadpoles
ABSTRACT. Nuclei from differentiated intestinal epithelium cells of feeding tadpoles and from control blastulae of Xenopus have been transplanted into enucleated recipient eggs. The differentiated sta...
journals.biologists.com
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Reposted by Grocott Lab
alliancegenome.bsky.social
Alliance of Genome Resources @alliancegenome.bsky.social · 5d
Nature has published an article on the crisis facing MODs
Model organism databases face budget cuts and closures www.nature.com/articles/d41...
@zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com
Model organism databases face budget cuts and closures
Beyond the crucial data they contain, these digital archives have provided an important space for academic communities to exchange ideas and resources.
www.nature.com
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aleksszczurek.bsky.social
Aleksander Szczurek @aleksszczurek.bsky.social · 16h
If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!
johninnescentre.bsky.social
John Innes Centre @johninnescentre.bsky.social · 2d
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.

www.jic.ac.uk/vacancies/po...

Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
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aruizherrera.bsky.social
Aurora Ruiz-Herrera @aruizherrera.bsky.social · 1d
RIP John Gurdon
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jamesbriscoe.bsky.social
James Briscoe @jamesbriscoe.bsky.social · 1d
Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
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grocottlab.bsky.social
Grocott Lab @grocottlab.bsky.social · 4d
Hi Kevin, this looks great! I managed to get my attempt to work with images other than 8-bit, but it’s still not quite there. I’ll definately check this out - it looks very slick!
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kwolbachia.bsky.social
Kevin Terretaz @kwolbachia.bsky.social · 4d
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
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gautamdey.bsky.social
Gautam Dey @gautamdey.bsky.social · 4d
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.

I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
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johninnescentre.bsky.social
John Innes Centre @johninnescentre.bsky.social · 5d
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
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cellsdev.bsky.social
Cells & Development @cellsdev.bsky.social · 5d
We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
Cell movements around the organizer/node after stage HH4. Fate maps of the ectodermal (dorsal) layer of the organizer/node, based on Selleck and Stern (1991) (Selleck and Stern, 1991). Cell movements of populations contributing to the organizer. Stages of early chick development referred to in the text. The diagrams show some of the features used to classify the stages in relation to primitive streak formation.
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evoldir.bsky.social
EvolDir @evoldir.bsky.social · 6d
The University of East Anglia seeks a Senior Research Associate in evolutionary ecology of animal behaviour and gut microbiome, with a salary of £38,784 to £46,049. Apply by 31 Oct 2025. Details: https://www.uea.ac.uk. #job
Find your place at UEA
The University of East Anglia is a home for everyone, a champion of interdisciplinarity that stands for equal opportunity in higher education. Join us at an Open Day.
www.uea.ac.uk
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natbiotech.nature.com
Nature Biotechnology @natbiotech.nature.com · 8d
Derivation of embryonic stem cells across avian species - @stemcell.keck.usc.edu go.nature.com/4gLAGcZ
Derivation of embryonic stem cells across avian species - Nature Biotechnology
Embryonic stem cells for chicken and seven other avian species are derived.
go.nature.com
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stowersinstitute.bsky.social
Stowers Institute @stowersinstitute.bsky.social · 7d
That’s a wrap on the Avian Model Systems Meeting at the Institute! 🐦✨

Scientists came together in KC to share discoveries & highlight the power of birds in advancing biology—from evolution to regeneration. Thanks to all who joined!💡🌍

#AvianModels2025 #Biology #Science
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maikbischoff.bsky.social
Maik Bischoff @maikbischoff.bsky.social · 14d
1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details
Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.
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grocottlab.bsky.social
Grocott Lab @grocottlab.bsky.social · 12d
Congratulations James et al, such a great tool!
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glover-lab.bsky.social
Glover lab @glover-lab.bsky.social · 12d
🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social
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nveits.bsky.social
Nisha Veits @nveits.bsky.social · 16d
How is developmental speed regulated ? 🪰

Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.

www.biorxiv.org/content/10.1...

A big thanks to everyone involved!
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webvision.bsky.social
Webvision @webvision.bsky.social · 16d
Webvision Has A New Home!

www.webvision.pitt.edu/2025/09/22/w...
A colorful mosaic of abstract spots arranged in squares that are derived from retinal research data.
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Reposted by Grocott Lab
alicegodden.bsky.social
Alice Godden @alicegodden.bsky.social · 22d
Our new paper is out in Dev Biol! 🎉 🐸🧬
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social
Schematic overview of our project. Dissection of Xenopus neural crest following morpholino knockdown of miRNA, then extraction of RNA for RNA-seq
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melaniedwhite.bsky.social
Melanie D. White @melaniedwhite.bsky.social · Aug 29
Bird’s eye view, literally. 🐦👁️ Glowing quail embryo eye for #FluorescenceFriday, #DevBio 🧪🔬
A microscope image showing a developing eye in a quail embryo. Actin is labelled in orange and nuclei are in cyan.
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gserranonajera.bsky.social
gserranonajera.bsky.social @gserranonajera.bsky.social · Aug 7
Hi bsky!

Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!

w/ A. Delahaye & ‪@bensteventon.bsky.social‬

shorturl.at/v01DO
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biorxiv-devbio.bsky.social
bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Aug 5
Gastruloids employ an alternative morphogenetic route to generate a posterior body axis on adherent substrates https://www.biorxiv.org/content/10.1101/2025.08.04.668470v1
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