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Guillaume Bourque @guilbourque.bsky.social · 11d

So inspiring to run with Darryl Fox to support Terry’s dream and the @marathonofhope.bsky.social

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Reposted by Guillaume Bourque

John Greally @greally.bsky.social · Aug 18

Looks like my book is available for pre-order:

a.co/d/cTKIwBN

#EpigeneticsBook

Amazon.com

a.co

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Guillaume Bourque @guilbourque.bsky.social · Aug 17

Dear @moriartylab.bsky.social, thanks for sharing your story! It was great to work with you at the beginning of the pandemic. I’m so impressed by how much you were able to do since then! You have always been truly committed to the cause. Please take care of yourself, it all starts with that!

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Guillaume Bourque @guilbourque.bsky.social · Aug 11

Excited for the start of the Croucher Retrotransposons meeting organized by Danny Leung in Hong Kong. First speaker, the King of Krabs!

projects.croucher.org.hk/advanced-stu...

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Guillaume Bourque @guilbourque.bsky.social · Jul 30

The issue that jumped at us in the current annotation of young LTR subfamilies in human, is that there was lot of variability in divergence rate (sometimes bimodal). That's what we tried to improve.

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Guillaume Bourque @guilbourque.bsky.social · Jul 23

We don’t claim to do it perfectly either… Just think it’s important to highlight the annotation problem and show that we have new tools (eg MPRA) to improve things.

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Guillaume Bourque @guilbourque.bsky.social · Jul 21

Is the annotation of viruses in the human genome accurate? We think not. Take a look at our new paper and let us know if you agree! www.science.org/doi/10.1126/...

A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage

A phylogenetic approach reveals cryptic LTR subfamilies and functional insights at nucleotide resolution in primates.

www.science.org

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Reposted by Guillaume Bourque

Nadav Ahituv @nadavahituv.bsky.social · Jul 1

Lentivirus massively parallel reporter assays integrate & enrich for specific sequences in the genome. We utilize this to test their epigenetic modifications & open chromatin alongside their regulatory activity. Amazing work by Zicong Zhang, Fumitaka Inoue & others.
www.biorxiv.org/content/10.1...

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Cis-regulatory elements (CREs) have a major effect on phenotypes including disease. They are identified in a genome-wide manner by analyzing the binding of transcription factors (TFs), various co-fact...

www.biorxiv.org

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Reposted by Guillaume Bourque

Adam Phillippy @aphillippy.bsky.social · May 12

The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples

Human Pangenome Reference Consortium @humanpangenome.bsky.social · May 12

📢 HPRC Release 2 is here!

Now with phased genomes from 200+ individuals, a 5x increase from Release 1.

Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:

humanpangenome.org/hprc-data-re...

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Reposted by Guillaume Bourque

Genome Canada @genomecanada.ca · Apr 25

Canada’s genomics community is rising to the challenge.

➡️ We’re sequencing 100K human genomes in 4 years to give researchers and innovators the data they need to transform health care.

Learn how the diversity of the dataset we build will set Canada apart as a global leader in #PrecisionHealth.

The Conversation Canada @ca.theconversation.com · Apr 23

A golden era for personalized medicine is approaching, but are we ready?

By understanding a patient’s unique genetic profile, biomarker readings and lifestyle information, doctors could tailor the most effective and safest treatments for that individual.

theconversation.com

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Reposted by Guillaume Bourque

Jonathan Göke @jonathangoeke.bsky.social · Apr 14

Excellent opportunity for PI positions at the Genome Institute of Singapore! Outstanding facilities, latest genomic technologies, strong and stable science funding. Junior candidates and established scientists are welcome to apply

A*STAR Genome Institute of Singapore (A*STAR GIS) @astar-gis.bsky.social · Apr 14

Are you passionate about advancing scientific research?🧬🔬 🧪
We are #hiring Principal Investigators who are ready to make a difference in the world of genomic research in AI, Computational biology to develop novel high throughput technologies for unveiling new insights into the biology of DNA or RNA!

A*STAR - Agency for Science, Technology and Research hiring Principal Investigators (GIS) in Singapore, Singapore | LinkedIn

Posted 11:59:37 AM. The Genome Institute of Singapore (GIS) is Singapore"s flagship institute for the genomic sciences.…See this and similar jobs on LinkedIn.

www.linkedin.com

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Guillaume Bourque @guilbourque.bsky.social · Apr 10

Bye bye magical Kyoto, see you next time!

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Guillaume Bourque @guilbourque.bsky.social · Apr 9

I’m very sorry to hear Cedric. Stay strong!

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Guillaume Bourque @guilbourque.bsky.social · Apr 1

Check out the new STR tool from @davidlougheed.bsky.social in the group! Works with both PacBio and Nanopore!

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Guillaume Bourque @guilbourque.bsky.social · Mar 16

#GoCanadaGo

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Guillaume Bourque @guilbourque.bsky.social · Mar 11

Haha, i thought the exact same thing!

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Guillaume Bourque @guilbourque.bsky.social · Mar 11

Maybe it's the better profile picture? :)

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Guillaume Bourque @guilbourque.bsky.social · Feb 26

Yeah, great one!

Quaid Morris @quaidmorris.bsky.social · Feb 26

Errands for RNA!

Randall Munroe @xkcd.com · Feb 26

RNA xkcd.com/3056

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Reposted by Guillaume Bourque

Gavin Sherlock @gsherloc.bsky.social · Feb 15

On January 6th, 1995, my (now ex) wife and I boarded a flight from Heathrow to JFK on a one way ticket. We had two suitcases and about $900 in cash - this was everything we owned and we were moving to the US. We thought it was maybe for 2-3 years. I had visited the US once, for a conference, and

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Reposted by Guillaume Bourque

Jonathan Göke @jonathangoeke.bsky.social · Feb 13

We are recruiting! We have an open position for a postdoctoral fellow to join our team at the Genome Institute of Singapore to work with long read RNA-Seq data. It’s a beautiful city state and outstanding research environment! More details here: jglab.org/postdoc-posi...

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Guillaume Bourque @guilbourque.bsky.social · Feb 5

Amazing! So moving. Such an important cause.

Jim Woodgett @jwoodgett.bsky.social · Feb 4

Two remarkable and iconic Canadians who brought Canada together, #TerryFox and #GordDownie of the #TragicallyHip. An anthem of our time. Cancer: Finish It.

Brad Wouters 🇨🇦 @bradwouters.com · Feb 4

youtube.com/watch?v=M4lp...

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Guillaume Bourque @guilbourque.bsky.social · Feb 1

Time for #MadeInCanada! madeinca.ca

TheHome | Made in CA

The made in Canada resource to quickly find Canadian products, services and retailers, so you can use your dollars to support the Canadian economy.

madeinca.ca

Guillaume Bourque @guilbourque.bsky.social · Jan 27

Thanks for sharing this very nice story of collaboration!

Anshul Kundaje @anshulkundaje.bsky.social · Jan 24

I wanted to write briefly about a very pleasant experience we recently had coordinating and collaborating closely on competing publications with 2 other teams. 1/

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Reposted by Guillaume Bourque

Deborah Bourc’his @deborahbourchis.bsky.social · Jan 27

Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...

The mobile genome: genetic and physiological impacts of transposable elements

www.embl.org

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Guillaume Bourque @guilbourque.bsky.social · Jan 5

Back in Barbados!

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