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Reposted by Ester Hammond

Simon Buczacki @sibucz.bsky.social · 3d

New CRUK Post-doc position in our group. #mutationalorder #multiomics #cancer.
my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

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Reposted by Ester Hammond

Conway Group @conway-group.bsky.social · 13d

Hypoxia-activated PROTACs (HAP-TACs) are online in @jacs.acspublications.org (pubs.acs.org/doi/10.1021/...)! Collborative work with Ester Hammond (@hammond-lab.bsky.social). Congrats to Marta Serafini, Sophie Twigger, George Delfas, Max Mallerman, Elliot Bailey & Ewen Calder (@ecalder.bsky.social).

Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells

Proteolysis targeting chimeras (PROTACs) have helped to establish proximity induction as an exciting strategy in drug discovery, and there are multiple clinical trials focused on this modality. Howeve...

pubs.acs.org

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Ester Hammond @hammond-lab.bsky.social · Jul 25

Great end to the week! Thank you to @sophietwigger.bsky.social for aiming high and getting us the Gold award. @oncology.ox.ac.uk

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Reposted by Ester Hammond

Oxford Cancer @oxfordcancer.bsky.social · Jul 18

Join us for our DPhil in Cancer Science Open Day on Tuesday 2nd September at 12:30pm to find out how a DPhil can be the next step in your cancer research career development!

Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk

www.eventbrite.co.uk/e/university...

University of Oxford - DPhil in Cancer Science Open Day

Join the Virtual DPhil in Cancer Science Open Day to hear more about Oxford’s world-leading research training

www.eventbrite.co.uk

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Reposted by Ester Hammond

Conway Group @conway-group.bsky.social · Jul 2

Our pre-print on the development of bivalent ligands for the TRIM24 bromodomain & PHD is now online chemrxiv.org/engage/chemr...

Congratulations to the authors: Michael Platt, Ekaterina Kot, Louise Martin, Antoine Wallabrègue, Liwen Song, Alistair Boyd, Lizbé Koekemoer, & @hammond-lab.bsky.social

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Reposted by Ester Hammond

Conway Group @conway-group.bsky.social · Jun 21

As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.

This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.

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Reposted by Ester Hammond

Conway Group @conway-group.bsky.social · Jun 21

Our pre-print on hypoxia-activated PROTACs (HAP-TACs) is now on ChemRvix: chemrxiv.org/engage/chemr...

We used the indolequinone bioreductive group to protect VHL- or CRBN-recruiting BRD4 degraders rendering them inactive. This group is removed selectively in hypoxia, revealing the active PROTAC.

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Reposted by Ester Hammond

Giulia Orlando @giuliaorlandogo.bsky.social · Jun 13

Exciting news!!! We are recruiting a RA to join my lab at
‪@oncology.ox.ac.uk‬ to study epigenetic reprogramming in stem cells and within the TME using colon organoids

www.oncology.ox.ac.uk/team/giulia-...

Deadline 2nd of July (my.corehr.com/pls/uoxrecru...)

Re-post are very welcome!

my.corehr.com

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Reposted by Ester Hammond

Andrew Blackford @andrewblackford.bsky.social · May 29

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms.

Please get in touch with your CV if you are interested; closing date: 27th June 2025.

More details here: candidate.hr-manager.net/ApplicationI...

Postdoctoral Research Associate in the Blackford Group

A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th

candidate.hr-manager.net

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Ester Hammond @hammond-lab.bsky.social · May 12

We really are fans of cross-disciplinary projects! Delighted to have contributed to some #PlantScience

New Phytologist @newphyt.bsky.social · May 12

#Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues

#PlantScience by Monica Perri, et al.

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...

@emilyflashman.bsky.social @daanweits.bsky.social @conway-group.bsky.social @hammond-lab.bsky.social

Bioreductive hypoxia-responsive chemical probes show fluorescence in hypoxic tissue of Arabidopsis.

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Ester Hammond @hammond-lab.bsky.social · May 7

I highly recommend working with @kleszczynsk.bsky.social If you're looking for a postdoc and interested in hypoxia and epigenetics take a look at nencki.edu.pl/job/the-nenc...

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN Accessibility toolsIncrease TextDecrease TextGrayscaleHigh contrastReset

nencki.edu.pl

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Reposted by Ester Hammond

University of Oxford Department of Oncology @oncology.ox.ac.uk · Mar 10

Meet @halaestephan.bsky.social 👩‍🔬🔬🧪

Hala is a postdoctoral researcher here at the oncology department, working on cancer immunology.

To mark #IWD25, Hala shares her STEM journey & her advice on how to thrive as a woman in academia.

@medsci.ox.ac.uk @hammond-lab.bsky.social
#InternationalWomensDay

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Ester Hammond @hammond-lab.bsky.social · Mar 6

Great opportunity for anyone looking for a post doc in Oxford - highly recommend!

Faraz Mardakheh @mardakheh.bsky.social · Mar 6

🚨Our post is now live! Apply and join us!

my.corehr.com/pls/uoxrecru...

Faraz Mardakheh @mardakheh.bsky.social · Feb 5

🚨Thanks to generous support from @cancerresearchuk.org, we have multiple postdoctoral positions available in our lab (www.mardakhehlab.info) @oxfordbiochemistry.bsky.social to study ribosomes synthesis in cancer. Get in touch if you’re interested + RT and spread the word! 📣 #cancer #RNA 🚨

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Reposted by Ester Hammond

Conway Group @conway-group.bsky.social · Feb 27

Great to see this collaborative work with @emilyflashman.bsky.social and @hammond-lab.bsky.social on @biorxivpreprint.bsky.social. Using our previously developed hypoxia probes (pubs.acs.org/doi/full/10....) to image hypoxia in plants.

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Reposted by Ester Hammond

University of Oxford @ox.ac.uk · Feb 7

Curious about doing a PhD? 🤔

Join Oxford's research community and work with academic staff on projects in a range of subject areas.

UNIQ+ research internships are now open for applications from UK undergraduates from under-represented and disadvantaged backgrounds.

More info ⬇️

What is a UNIQ+ Research Internship? | University of Oxford

What is UNIQ+?UNIQ+ Research Internships are designed to provide students from under-represented and disadvantaged backgrounds who are ordinarily resident in the UK with the opportunity to experience

www.ox.ac.uk

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Reposted by Ester Hammond

University of Oxford Department of Oncology @oncology.ox.ac.uk · Jan 22

The MSc in Medical Physics with Radiobiology at @oncology.ox.ac.uk welcomes students looking to kickstart a career in medical physics research, clinical practice, or industry.

Find out more: tinyurl.com/4a4km74v

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Reposted by Ester Hammond

The Dunn School, Oxford @dunnschool.bsky.social · Jan 22

ICYMI

We are recruiting a new Associate Professor in cell and molecular biology, with a preference for immunology, inflammation and/or infection - all defined broadly

Come and be our colleague!

Deadline 28 Feb, please spread the word!

www.path.ox.ac.uk/vacancy/asso...

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Ester Hammond @hammond-lab.bsky.social · Jan 7

Congratulations to the new Dr Twigger @sophietwigger.bsky.social and many thanks to Angie Russell and Navita Somaiah for examining. Let the celebrations commence

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Ester Hammond @hammond-lab.bsky.social · Jan 3

Great start to 2025. Tumor hypoxia promotes immune evasion by autophagy-mediated downregulation of MHC class I expression leading to reduced antigen presentation. Great work from @halaestephan.bsky.social www.embopress.org/doi/full/10....

Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation | The EMBO Journal

imageimageHypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor hypoxia promotes immune evasion by autophagy-mediated downregulation ...

www.embopress.org

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Reposted by Ester Hammond

Eileen Parkes @eileenparkes.bsky.social · Dec 30

Are you full of ideas, thinking about applying for fellowships and looking for a home i.e. junior group leader position? We're recruiting! my.corehr.com/pls/uoxrecru...

Job Details

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Ester Hammond @hammond-lab.bsky.social · Dec 16

We enjoyed a great holiday celebration, throwing some darts (some better than others) and eating lots. Happy holidays to all @sophietwigger.bsky.social @katroseworth.bsky.social @olivierzanier.bsky.social @brightw.bsky.social @halaestephan.bsky.social @edpetrosyan.bsky.social @chuminz.bsky.social

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Ester Hammond @hammond-lab.bsky.social · Dec 10

Exciting opportunity to establish your own research group in the Department of Oncology at Oxford. Please spread the word

my.corehr.com/pls/uoxrecru...

Job Details

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Reposted by Ester Hammond

Aga Gambus @agagambus.bsky.social · Dec 9

Still a month left to apply for one of our fully funded PhD positions in Birmingham, UK. EU / International students welcomed. DNA replication, biochemistry, structural biology. Supportive, multinational team. Please RT (not just ❤️). Thank you!

Aga Gambus @agagambus.bsky.social · Nov 27

Two fully funded PhD opportunities in our lab. Interdisciplinary, DNA replication, cancer research, structural biology… deadlines in early Jan. Open to international students. t.co/WEJJIU4zU4

www.findaphd.com/phds/project...

https://www.findaphd.com/phds/project/inhibitor-of-donson-gins-interaction-as-an-experimental-tool-and-potential-anticancer-strategy/?p178853

t.co

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Reposted by Ester Hammond

keithcaldecott.bsky.social @keithcaldecott.bsky.social · Dec 3

Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on [email protected]

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Ester Hammond @hammond-lab.bsky.social · Nov 27

Really was fab, enjoyed it a lot

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