Lightnews — Scholar-powered news

Reposted by HIPC

La Jolla Institute for Immunology (LJI) @lji.org · Aug 14

Congratulations to LJI Professor Alessandro Sette, Dr.Biol.Sci. (@settelab.bsky.social)!

The Procter Prize from Sigma Xi honors Dr. Sette's impact as an immune system researcher and a science communicator! bit.ly/3Jhqe0s #Immunology #science #health #medicine #SanDiego #STEM

LJI Professor Alessandro Sette receives William Procter Prize for Scientific Achievement

Prestigious prize recognizes Sette's accomplishments as a researcher and scientific communicator

bit.ly

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Ana Fernandez-Sesma @sesmalab.bsky.social · Aug 19

Looking forward to my visit!

Dr. Arnaldo Díaz @ajdiazphd.bsky.social · Aug 18

Join us on Sept 18th as we welcome Dr. @sesmalab.bsky.social to our PROVIDES Seminar Series. Dr. Fernández-Sesma will lead a research seminar on Immune responses to dengue virus infection and vaccination. Don’t miss the opportunity to learn about her research efforts.

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HIPC @hipcproject.bsky.social · Aug 6

Come get your curated #immune #assays from 1,000s of human subjects at our website
immunespace.org
🧪 #immunology #IDSky #ImmuneSky
immunespace.org/query/filters

giphy.com/gifs/Giflyti...

Analyze Lucky Charms GIF by Giflytics - Find & Share on GIPHY

Discover & share this Analyze Lucky Charms GIF by Giflytics with everyone you know. GIPHY is how you search, share, discover, and create GIFs.

giphy.com

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HIPC @hipcproject.bsky.social · Aug 4

3 of our recent studies deal with risk for death in #COVID19.
Two from Frontiers of Medicine.
1. frontiersin.org/journals/med...
2. frontiersin.org/journals/med...
One from @jci-insight.bsky.social

pubmed.ncbi.nlm.nih.gov/40608426/
All part of the IMPACC project. Some collaborators on map.

Map of United States shows many contributors to covid19 study called IMPACC. Study was of hospitalized patients testing their immune responses.

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HIPC @hipcproject.bsky.social · Jul 31

More insights from #IMPACC studies, including polymorphism that might protect in #covid19 in online publication.
Authors include: @skleinstein.bsky.social @bjoernpeters.bsky.social @sesmalab.bsky.social @vivianasimonlab.bsky.social @joanndarce.bsky.social ++ others
insight.jci.org/articles/vie...

Screen shot of paper entitled "MICBG4064A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury." From JCI Insight publication.

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HIPC @hipcproject.bsky.social · Jul 30

Thanks @jschaenmanmd.bsky.social for your comments and sorry if we didn't tag every author. There were too many! #covid19 #treatment #vulnerable

Joanna Schaenman, MD, PhD @jschaenmanmd.bsky.social · Jul 29

Great to see this work be published, it has been such a wonderful opportunity to be involved with the #IMPACC network - these important findings re immune response to #COVID will be useful for future pandemics especially for vulnerable populations @ast-idcop.bsky.social @niaidnews.bsky.social

HIPC @hipcproject.bsky.social · Jul 29

Our collaborators identify chief predictor of #covid19 severity + death. Many authors include members of #IMPACC network: @rrmsky.bsky.social @bjoernpeters.bsky.social @skleinstein.bsky.social @sesmalab.bsky.social
@joanndarce.bsky.social @droferlevy.bsky.social
www.frontiersin.org/journals/med...

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Joanna Schaenman, MD, PhD @jschaenmanmd.bsky.social · Jul 29

Great to see this work be published, it has been such a wonderful opportunity to be involved with the #IMPACC network - these important findings re immune response to #COVID will be useful for future pandemics especially for vulnerable populations @ast-idcop.bsky.social @niaidnews.bsky.social

HIPC @hipcproject.bsky.social · Jul 29

Our collaborators identify chief predictor of #covid19 severity + death. Many authors include members of #IMPACC network: @rrmsky.bsky.social @bjoernpeters.bsky.social @skleinstein.bsky.social @sesmalab.bsky.social
@joanndarce.bsky.social @droferlevy.bsky.social
www.frontiersin.org/journals/med...

Frontiers | Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic threatened public health and placed a significant burden on medical resources. The Immunophenoty...

www.frontiersin.org

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HIPC @hipcproject.bsky.social · Jul 29

Our collaborators identify chief predictor of #covid19 severity + death. Many authors include members of #IMPACC network: @rrmsky.bsky.social @bjoernpeters.bsky.social @skleinstein.bsky.social @sesmalab.bsky.social
@joanndarce.bsky.social @droferlevy.bsky.social
www.frontiersin.org/journals/med...

Frontiers | Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic threatened public health and placed a significant burden on medical resources. The Immunophenoty...

www.frontiersin.org

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Florian Wimmers @therealimmunecell.bsky.social · Jul 24

Postdoc Opening – Cancer & Immune Interactions
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.

🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)

Apply by Aug 25

www.nature.com/naturecareer...

Postdoctoral Researcher: Cancer-Immune Interactions in Human Organoid Systems - Tübingen, Baden-Württemberg (DE) job with University of Tübingen | 12841595

We are seeking a highly motivated Postdoctoral Researcher to determine the impact of cancer on immune responses in human organoid systems.

www.nature.com

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HIPC @hipcproject.bsky.social · Jul 24

Graphical abstract for #polymorphism associated with severe #COVID19

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HIPC @hipcproject.bsky.social · Jul 24

Our collaborators unpacked a CD16 #polymorphism linked to #severe #covid19
Authors include: @skleinstein.bsky.social @bjoernpeters.bsky.social @sesmalab.bsky.social
@vivianasimonlab.bsky.social
@joanndarce.bsky.social
IMPACC group
insight.jci.org/articles/vie...

JCI Insight - High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19

insight.jci.org

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Prof. Shane Crotty @profshanecrotty.bsky.social · Jul 21

Beyond flu, intranasal platforms are also being develop for a range of pathogens.

Understanding immune dynamics at the tissue site, and being able to directly measure them in humans, may dramatically improve development of vaccines that elicit robust protection against respiratory viruses.

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Prof. Shane Crotty @profshanecrotty.bsky.social · Jul 21

In our new study we show local B-cell immunity and durable memory following live-attenuated influenza intranasal vaccination of humans. We utilized minimally invasive swabbing of human upper airway, following seasonal intramuscular or nasal (FluMist) flu vaccinations
www.biorxiv.org/content/10.1...

Local B-cell immunity and durable memory following live-attenuated influenza intranasal vaccination of humans

Seasonal influenza vaccines are most frequently delivered as intramuscular inactivated vaccines which elicit systemic responses against the immunodominant hemagglutinin (HA) head domain. An intranasal...

www.biorxiv.org

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HIPC @hipcproject.bsky.social · Jul 21

Our collaborator Eva Harris
+ others describe way to distinguish #westnile virus infection by anti-premembrane antibodies in Nicaraguan children.
WNV is difficult to distinguish from other flaviviruses in sera.

journals.asm.org/doi/10.1128/...

Identification of West Nile virus infection by anti-premembrane antibodies in Nicaraguan children prior to 2007–2009 | Microbiology Spectrum

Since its arrival to North America in 1999, West Nile virus (WNV) has caused multiple outbreaks in birds and humans, with thousands of human cases in the USA and Canada, whereas in Latin America, WNV ...

journals.asm.org

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Krishnaswamylab.org @krishnaswamylab.bsky.social · Jul 17

Good morning from Vancouver! 🌞⛰️ We’re at #ICML2025 presenting at GenBio + MAS. Come chat with us about machine learning in biology!

With @RobertXiangruTang, @ChenLiu, @DanqiLiao. Views like this make the science even sweeter.🧬🧠

#ML #ComputationalBiology #ICML #Vancouver

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HIPC @hipcproject.bsky.social · Jul 18

Our lab door has a "data door" that lets you download for #free 1000+ assays measuring #immune response.
immunespace.org

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Benaroya Research Institute @benaroyaresearch.bsky.social · Jul 15

(1/8): New findings published this week in @jama.com Pediatrics are reshaping how we understand severe childhood asthma — especially in urban, low-income communities. 🧵

Image of BRI’s Matthew C. Altman, MD, MPhil; headline reads: “Asthma Exacerbations in Children Caused by Multiple Molecular Pathways”

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HIPC @hipcproject.bsky.social · Jul 17

Hello to #ASV2025 and be sure to use our #free #data
You can upload from immunespace.org
Including multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping + many computational tools. #virology

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HIPC @hipcproject.bsky.social · Jul 9

Our collaborator Purvesh Katri, and others, discover a #signature of #immune health.

med.stanford.edu/news/all-new...

@stanfordimmunology.bsky.social

Immune ‘dysregulation’ present prior to infection predicts severe responses

Stanford Medicine-led research finds that a gene signature capturing immune health or dysfunction can forecast patient outcomes following subsequent viral or bacterial infections.

med.stanford.edu

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HIPC @hipcproject.bsky.social · Jul 7

We are a network of 8 big members:
@lji.org @columbiamed.bsky.social @yalemedicine.bsky.social MIT @seattlechildrens.bsky.social
@stanfordimmunology.bsky.social
Icahn Mt. Sinai @benaroyaresearch.bsky.social
You can upload our #free data at immunespace.org
Image from 2020. 🧪 #ImmuneSky

Against a green background, a pattern of consecutive rings has small round faces or icons. Each represents an institution or person who is connected with the center image - Human Immunology Project Consortium. A gov't financed research project aimed at understanding the human immune system.

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HIPC @hipcproject.bsky.social · Jul 2

Our collaborators @rgottardo.bsky.social Peter Sims and Ken Stuart (and others) develop tool ADTNorm, a method of helping noisy CITE-seq data to be "normalized"
#antibody
#ImmuneSky

nature.com/articles/s41...

#CITEseq #SingleCell #ADTNorm

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications

Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...

nature.com

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Raphael Gottardo @rgottardo.bsky.social · Jul 1

🧬 New paper out!
🔗 www.nature.com/articles/s41...

Frustrated by noisy CITE-seq data?
ADTNorm helps normalize it and introduces a staining index to assess antibody quality.

Great work by former postdoc Ye Zheng. Supported by @hipcproject.bsky.social

#CITEseq #SingleCell #ADTNorm

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications

Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...

www.nature.com

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Ruth Montgomery @rrmsky.bsky.social · Jul 1

Well annotated, curated, multiparameter FREE #immunology data, folks!

HIPC @hipcproject.bsky.social · Jun 30

Our project spans 8+ institutions, with human cohorts studied with multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping of leukocyte subsets + many computational methods.
Get our #data for your own investigations.
#ImmuneSky #IDsky
immunespace.org

Page shows information about Human Immunology Project Consortium and the data from 174 studies, 52 diseases. https://immunespace.org

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HIPC @hipcproject.bsky.social · Jun 30

Very glad to see our own collaborator @virusesimmunity.bsky.social honored among all of these. #science #immunology #virology #IDSky

Lucy Burns @lucyburns.bsky.social · Jun 30

Every 4th of July, Carnegie Corporation of New York celebrates remarkable Americans — all naturalized citizens — who have enriched and strengthened our democracy through their actions and contributions.

Originating from 16 countries, here is the Carnegie 2025 Class of Great Immigrants:

2025 Great Immigrants | Carnegie Corporation of New York

www.carnegie.org

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HIPC @hipcproject.bsky.social · Jun 30

Our project spans 8+ institutions, with human cohorts studied with multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping of leukocyte subsets + many computational methods.
Get our #data for your own investigations.
#ImmuneSky #IDsky
immunespace.org

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