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Reposted by Holly Gildea

Ashley Frakes @afrakes.bsky.social · 14d

🚨Please share! We are hiring a post-doc! 🪱 🐀
Job posting: www.training.nih.gov/jobs/pdf-gb-...
Lab Website: www.niddk.nih.gov/research-fun...
NIH Trainee info: www.training.nih.gov

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Holly Gildea @hollygildea.bsky.social · Jul 22

Some of the coolest work I’ve ever been a (small) part of from @melcooperphd.bsky.social - it is a joy to be “in network” with you!

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Jul 22

Astrocytes connect specific brain regions through plastic gap junctional networks https://www.biorxiv.org/content/10.1101/2025.07.18.665573v1

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Reposted by Holly Gildea

Priya Prakash @pryprk.bsky.social · May 19

Happy to share that our work "Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease" is out now @cp-immunity.bsky.social! ➡️ www.cell.com/immunity/ful...

Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease

Why microglia stop reducing amyloid deposits from Alzheimer’s disease (AD) brains is unknown. Prakash, Manchanda, et al. show that microglia increase their lipid droplets and lose their phagocytic cap...

www.cell.com

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Holly Gildea @hollygildea.bsky.social · Mar 10

Our new work on astrocyte responses in glaucoma is out today! A tour de force of tissue clearing and analysis by @melcooperphd.bsky.social. It's one of those stories that leads to even more great questions, so stay tuned!

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

urldefense.com

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Reposted by Holly Gildea

Philip Hasel @philiphasel.bsky.social · Feb 24

Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...

Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates

Hasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...

www.cell.com

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Holly Gildea @hollygildea.bsky.social · Feb 21

Excited to share our review on astrocyte aging, out today! Hopefully the only Friday surprises this week are Liddelow lab publications! 🧪 #neuroskyence @liddelowsa.bsky.social

Mechanisms of astrocyte aging in reactivity and disease - Molecular Neurodegeneration

Normal aging alters brain functions and phenotypes. However, it is not well understood how astrocytes are impacted by aging, nor how they contribute to neuronal dysfunction and disease risk as organis...

molecularneurodegeneration.biomedcentral.com

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Reposted by Holly Gildea

John Green @johngreensbluesky.bsky.social · Feb 17

The average person with the flu gives it to around 1.4 people. The average person with measles gives it to between 12 and 18 people.

WHO @who.int · Feb 17

Measles cases continue to surge globally, putting millions of children at risk.

More than 10 million people globally were infected with measles in 2023, a 20% increase from the previous year.

bit.ly/48SAtkf

Measles is preventable with two doses of measles vaccine; yet more than 22 million children missed their first dose of measles vaccine in 2023. Globally, an estimated 83% of children received their first dose of measles vaccine last year, while only 74% received the recommended second dose.

More than 10 million people globally were infected with measles in 2023

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Holly Gildea @hollygildea.bsky.social · Feb 8

When I said “science is over we can all go home” it was a JOKE! I was KIDDING! 😭😭😭😭

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Holly Gildea @hollygildea.bsky.social · Feb 6

Contact your representatives using this link! An easy way to take action

Society for Neuroscience @sfn.org · Feb 6

🔗 Contact your representatives using SfN’s Action Alert Center: bit.ly/413khdN

#NeuroSky

Available Actions

www.sfn.org

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Reposted by Holly Gildea

Angeline J. Dukes, PhD @heydrdukes.bsky.social · Feb 2

Happy #BlackHistoryMonth! ✨

They’ll never be able to take away the impact and contributions of Black scientists, no matter how hard they try.

So each week this month, I’ll be highlighting a few #BlackInNeuro scientists for you to learn about, celebrate their work, & follow 👩🏾‍🔬👨🏽‍🔬

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Holly Gildea @hollygildea.bsky.social · Jan 29

I was a public school free lunch kid in a SNAP family who went to college on Pell grants & work study. My graduate education was funded by an NIH T32, the NSF GRFP, and an NIH F99, the K00 portion of which still funds me as a postdoc! I quite literally would not be here without federal funding.

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Reposted by Holly Gildea

Harmit Singh Malik @harmitmalik.bsky.social · Jan 28

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.

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Reposted by Holly Gildea

Celia Ford @celiaford.bsky.social · Jan 7

Are you a scientist or science policy expert who's feeling a little nervous about federal research funding, as the next administration prepared to take over? I want to hear from you.

[reposting would be greatly appreciated!]
#neuroskyence #medsky #academicsky

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Holly Gildea @hollygildea.bsky.social · Jan 8

Highly recommend submitting session ideas for SfN 2025! I had an excellent time chairing a minisymposium this past year, and it was both a great opportunity and a perfect way to hear all of the talks I personally wanted to hear! Deadline for this year is Jan 22 @sfn.org

Neuroscience 2025

www.sfn.org

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Reposted by Holly Gildea

Javier Apfeld @javierapfeld.bsky.social · Jan 6

Worm people: We are looking for a postdoc to join the C. elegans Mentor Match committee.

This is a great opportunity to shape a global mentorship program and gain leadership experience.

📩 DM or email me and Andrea Calixto if interested—and please spread the word! 🙌

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Holly Gildea @hollygildea.bsky.social · Jan 2

Receiving high-quality, attentive, productive feedback from reviewers: 🤩😍🥳
Actually incorporating said feedback: 😭

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Holly Gildea @hollygildea.bsky.social · Dec 30

Gift link for the manuscript available here! authors.elsevier.com/c/1kK24L7PXq...

authors.elsevier.com

Holly Gildea @hollygildea.bsky.social · Dec 25

Congrats to Cory Pender of @dillinlab.bsky.social for this work out today! The mechanism ended up being both super cool and unexpected, and it was a joy to be involved with!

Perception of a pathogenic signature initiates intergenerational protection

Transmission of immune responses from one generation to the next represents a powerful adaptive mechanism to protect an organism’s descendants. Parent…

www.sciencedirect.com

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Reposted by Holly Gildea

Priya Prakash @pryprk.bsky.social · Dec 17

Happy to share our review on how different lipids shape microglial biology in #GLIA journal. 💫 onlinelibrary.wiley.com/doi/full/10....

👉🏽with Gaurav Chopra, Caitlin Randolph, and @katherinewalker.bsky.social

Lipids: Emerging Players of Microglial Biology

Lipids are crucial in mediating microglial metabolism and function. The microglial lipidome is vast and complex, with over 10,000 lipid species. We discuss key lipid classes and their roles in m...

onlinelibrary.wiley.com

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Holly Gildea @hollygildea.bsky.social · Dec 15

🙋🏻‍♀️

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Holly Gildea @hollygildea.bsky.social · Dec 5

Agreed! Synapse one is cool! Arguably they could stand more secondary/tertiary processes as well 😂

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Holly Gildea @hollygildea.bsky.social · Nov 26

Very glad that everyone finally made the switch from the bird site so that I can finally find important papers I desperately need to read while procrastinating again!

Reposted by Holly Gildea

Emily C. Hughes @emilyhughes.bsky.social · Jan 9

immense respect to this science teacher for seeing his opportunity and grabbing onto it with both hands

New YorkTimes screenshot
Headline: Science Teacher Finds Missing Piece of Boeing Jet’s Fuselage in His Yard
Subhed: Bob Sauer said that his 50-foot cedar trees had acted on the same scientific principle as an airbag, disrupting the door plug’s fall in an act known in physics as impulse.

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Holly Gildea @hollygildea.bsky.social · Dec 21

They both say B! Clearly the anti-WH agenda 😂

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Holly Gildea @hollygildea.bsky.social · Dec 19

Lots of thoughts about this from an aging bio perspective - overall, anti-aging treatments target shared mechanisms that cause cognitive aging, and I think cog. aging is MUCH more mutable than total age. I don't think we're likely to see this as a result of anti aging treatments.

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