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Holmes Lab @holmeslab-bhi.bsky.social · 1d

Holmes Lab + Parkes Lab had a great fall social a few weeks back!! Pottery painting (including an awesome brain-art mug by @ambrains.bsky.social 🧠). Thank you to our awesome mentors @avramholmes.bsky.social and @lindenmp.bsky.social for encouraging these great lab events! 💫

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Avram Holmes @avramholmes.bsky.social · Sep 5

The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.

jobs.rutgers.edu/postings/209...

Human Neuroimaging Faculty Positions in Rutgers Brain Health Institute

The Center for Advanced Human Brain Imaging Research (CAHBIR), a component of the Rutgers Brain Health Institute (BHI) on the Busch campus in Piscataway, NJ, is recruiting for two open rank (Assistant...

jobs.rutgers.edu

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Avram Holmes @avramholmes.bsky.social · Sep 4

Latest
@holmeslab-bhi.bsky.social
preprint. Here, integrating genetic, post-mortem, and diffusion MRI data, Rowena Chin examines the heritability and cellular associates of late-life decline in white matter integrity.
@cahbir.bsky.social @rutgersbhi.bsky.social

www.biorxiv.org/content/10.1...

The cellular associates of late life changes in white matter microstructure

The microstructural architecture of white matter supporting information flow across local circuits and large-scale networks changes throughout the lifespan. However, the genetic and cellular factors u...

www.biorxiv.org

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Holmes Lab @holmeslab-bhi.bsky.social · Aug 21

Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!

With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social

The Transmitter @thetransmitter.bsky.social · Aug 20

When powering fMRI studies, sample size is king, but scan duration can also be a powerful tool, improving phenotypic prediction and cost-efficiency, a new analysis shows

By @claudia-lopez.bsky.social

#neuroskyence

www.thetransmitter.org/fmri/longer-...

Longer fMRI brain scans boost reliability—but only to a point

Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and cost-effective way.

www.thetransmitter.org

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Shaoshi Zhang @shaoshiz.bsky.social · Jul 17

🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:

Thomas Yeo @bttyeo.bsky.social · Jul 17

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...

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Nico Dosenbach @ndosenbach.bsky.social · Jul 17

This new Yeo Lab tool should immediately and permanently replace sample-size-only power calculations for functional MRI.

www.nature.com/articles/s41...

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Thomas Yeo @bttyeo.bsky.social · Jul 17

Everyone should try out the Trandiagnostic Connectome Project (TCP) dataset! Openly available on @openneuro.bsky.social

Sidhant Chopra @sidchop.bsky.social · Jul 17

V useful paper by @bttyeo.bsky.social @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social in @nature.com. Scan longer if you want to predict behav using fMRI and save $.

Great use of the TCP data: (pmc.ncbi.nlm.nih.gov/articles/PMC...).

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Nature @nature.com · Jul 17

Nature research paper: Longer scans boost prediction and cut costs in brain-wide association studies

go.nature.com/3IME4aA

Longer scans boost prediction and cut costs in brain-wide association studies - Nature

Although the number of participants is important for phenotypic prediction accuracy in brain-wide association studies using functional MRI, scanning for at least 30 min offers the greatest cost effectiveness.

go.nature.com

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Holmes Lab @holmeslab-bhi.bsky.social · Jun 28

And Amber @ambrains.bsky.social is killing it as the Art Exhibition Manager for the OHBM Brain Art SIG! 🎨

Major kudos to all of you, and have fun at the last day!! #OHBM

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Holmes Lab @holmeslab-bhi.bsky.social · Jun 28

Ashlea @ashleasegal.bsky.social is doing amazing work as the Chair of the OHBM Student and Postdoc Special Interest Group (SP-SIG), which has also been putting out amazing programming all year long 😍

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Holmes Lab @holmeslab-bhi.bsky.social · Jun 28

Holmes Lab is representing at #OHBM2025! 🧵 Loic
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠

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Sidhant Chopra @sidchop.bsky.social · Jun 4

Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾

Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · Jun 4

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉

www.nature.com/articles/s41...

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The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data

Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry

www.nature.com

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Cedric Boeckx @cedricboeckx.bsky.social · Jun 7

Very cool preprint examining how brain networks and cognition co-evolve during development
By @bttyeo.bsky.social @lucinauddin.bsky.social @avramholmes.bsky.social @elvisha.bsky.social & colleagues
🧪🧠
www.biorxiv.org/content/10.1...

Convergent and divergent brain-cognition relationships during development revealed by cross-sectional and longitudinal analyses in the ABCD Study

How brain networks and cognition co-evolve during development remains poorly understood. Using longitudinal data collected at baseline and Year 2 from 2,949 individuals (ages 8.9-13.5) in the Adolesce...

www.biorxiv.org

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Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · Jun 4

Check out my newest preprint to see the TCP dataset in action! 🤘🧠

Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease: www.biorxiv.org/content/10.1...

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Holmes Lab @holmeslab-bhi.bsky.social · Jun 10

If you missed it, our open source 240-person transdiagnostic dataset is now published. Read the data release 👇👇 + find it on:
OpenNeuro: openneuro.org/datasets/ds0...
NDA: nda.nih.gov/study.html?i...

Sidhant Chopra @sidchop.bsky.social · Jun 4

Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾

Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · Jun 4

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉

www.nature.com/articles/s41...

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Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · Jun 4

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉

www.nature.com/articles/s41...

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The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data

Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry

www.nature.com

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Avram Holmes @avramholmes.bsky.social · Jun 4

Our latest @holmeslab-bhi.bsky.social data release is now "live!" Available on NDA and @openneuro.bsky.social and spearheaded by @carrisacocuzza.bsky.social, @sidchop.bsky.social, and Connor Lawhead.

Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · Jun 4

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉

www.nature.com/articles/s41...

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The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data

Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry

www.nature.com

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · May 28

Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease https://www.biorxiv.org/content/10.1101/2025.05.23.655864v1

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Avram Holmes @avramholmes.bsky.social · May 30

New @holmeslab-bhi.bsky.social paper led by @carrisacocuzza.bsky.social. Brain dynamics across task and rest can be used to predict the presence of psychiatric illness (case/control status), diagnostic labels, and multi-dimensional symptom fingerprints. @rutgersbhi.bsky.social @rutgersu.bsky.social

Carrisa V. Cocuzza, PhD (she/her) @carrisacocuzza.bsky.social · May 30

🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘

www.biorxiv.org/content/10.1...

Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇

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Holmes Lab @holmeslab-bhi.bsky.social · Jun 2

Check out Carrisa's new paper! An amazing investigation into brain network dynamics across psychiatric symptoms🔥🔥
+ using our new open dataset the Transdiagnostic Connectome Project (TCP) 🔛 openneuro.org/datasets/ds0...

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Holmes Lab @holmeslab-bhi.bsky.social · May 29

Great lab outing to Duke Farms yesterday! Happy spring from the Holmes + Parkes labs 😄 🌸

With @lindenmp.bsky.social @avramholmes.bsky.social @carrisacocuzza.bsky.social @ahmadbeyh.bsky.social @loiclabache.bsky.social (+ Amber Howell & Rachel Cooper)

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Avram Holmes @avramholmes.bsky.social · May 20

We're searching for a lead Research MRI technologists at @cahbir.bsky.social! Please share and pass along to any/all interested folks.

Center for Advanced Human Brain Imaging Research @cahbir.bsky.social · May 20

CAHBIR at Rutgers University is looking for a Lead Research MRI Technologist. CAHBIR is a research-only facility that focuses on neuroimaging, and other MR imaging projects. If you are interested, see the information flier linked, and apply online!

go.rutgers.edu/mri-tech

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Holmes Lab @holmeslab-bhi.bsky.social · May 24

Last month Linden Parkes and his team put out an amazing new work! They build on their network control theory model & improved whole-brain structure-function coupling

Check this 🧵 for a summary 🔥

www.biorxiv.org/content/10.1...

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Thomas Yeo @bttyeo.bsky.social · Apr 11

While the world burns, we cook up a new preprint! doi.org/10.1101/2025...

Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N

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Holmes Lab @holmeslab-bhi.bsky.social · Apr 15

Newest #preprint from Holmes lab postdoc @loiclabache.bsky.social 🔥

Loïc Labache @loiclabache.bsky.social · Apr 12

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization

🔗 doi.org/10.1101/2025...

🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇

#neuroskyence

The molecular and cellular underpinnings of human brain lateralization

Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...

doi.org

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