Holthuis Lab
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holthuislab.bsky.social
Holthuis Lab
@holthuislab.bsky.social
Lipid cell biologists who love to hang out with chemists & computer simulations experts to grasp the complex behavior of membranes
Modern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026 meetings.embo.org/event/26-lip...
January 18, 2026 at 12:31 PM
Our data collectively support a model according to which VPS13C acts upstream of OSBP/ORP lipid transport proteins to orchestrate bulk lipid transport in synchrony with lysosomal damage and repair, thereby maintaining lysosome integrity
October 25, 2025 at 1:40 PM
As ER-lysosome contact sites bridged by VPS13C have a gap width that cannot be resolved by light microscopy, we used a ratiometric approach to simultaneously trace fluorescence levels of ER-derived lipids & ER membrane proteins on the surface of damaged lysosomes containing pHrodo-labeled microbeads
October 25, 2025 at 1:31 PM
🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...
October 17, 2025 at 3:18 PM
I am proud to 📣 today’s superb thesis defense by Milena Wessing on “Molecular dissection of ceramide-induced apoptosis: a bottom-up approach”. Two papers describing Milena’s heroic efforts are close to submission. It was a privilege serving as her “Doktorvater” 🥂
October 14, 2025 at 6:37 PM
I am pleased to 📣 today’s superb thesis defense by Christian Schroer on “Chemical strategies for studying lipid signaling and transport”. Part of his work was recently published in the JLR; the other part will follow soon. A very proud and somewhat tipsy “Doktorvater” 🥂
September 30, 2025 at 6:53 PM
🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏
February 26, 2025 at 10:00 PM
"Democracy needs Science. Science needs Democracy". Germany is facing a landmark federal election. I am proud to be part of a university whose presidential board takes a clear stance that argues from the self-image of science. Please share👇
February 17, 2025 at 9:07 AM
MD simulations and experiments in cells reveal core structural determinants that govern binding of Hexokinase I to mitochondrial VDACs, a liaison with far-reaching physiological implications. Another great collaborative effort with @melolab.bsky.social and @cg-martini.bsky.social! rdcu.be/d9lO8
February 11, 2025 at 12:37 PM
🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏
January 25, 2025 at 2:34 PM
📯📯Do not miss the Sphingolipid Biology Young Researcher Contest on Tue 14th January! Free registration at sphingolipidbiology.com/registrations. Please repost!📯📯
January 10, 2025 at 9:48 AM
January 3, 2025 at 6:08 PM