Harriette Van Spall MD MPH 🇨🇦
@hvanspall.bsky.social
680 followers 130 following 120 posts
Cardiologist, Clinical Trialist McMasterU. Heart failure, Cardiometabolic Disease, Implementation Science. Editor Circulation.
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hvanspall.bsky.social
The eligibility criteria in a trial ensure that appropriate patients are selected. A screening 24 hour Holter monitor will be used to guide patient selection for this trial. Patient will have the comorbidities that are common with this condition.
hvanspall.bsky.social
Thank you, we have already enrolled a handful of patients. The pacing rate will be personalized using a simple formula that was tested in an early phase trial.
hvanspall.bsky.social
#Medtronic press release on our pivotal #ELEVATE-HFpEF RCT which will test the efficacy & safety of a personalized elevated #pacing rate (based on LVEF & height) in #HFpEF

75 countries

2 patients enrolled already (AUS & US)

Methods to be presented at #HFSA25

news.medtronic.com/2025-09-15-M...
hvanspall.bsky.social
FDA announces approval for #semaglutide 2.4 mg sc weekly for #MASLD based on results of the #ESSENCE #RCT.

Did you know that #CVD is the leading cause of death in patients with #MASLD?

Common mechanisms & now, common treatments for #CKLM diseases
www.novonordisk.com/news-and-med...
Reposted by Harriette Van Spall MD MPH 🇨🇦
jonpheart.bsky.social
📣 How is the American Heart Association fighting for medical research & patient care on Capitol Hill? @ahascience.bsky.social #CardioSky #AHA

Join Heart Powered: The AHA is Advocating for You
🗓️ June 26 | 🕒 3 PM ET
🎙️ Dr. Bradley Marino & Emily Hubelowski

🔗 Register: heart.zoom.us/webinar/regi...
hvanspall.bsky.social
I love my outdoor #office, where work and play are fully intertwined!

What does your #Saturday morning look like?

#HappySeason #HomeSweetHome #JoyInWork
hvanspall.bsky.social
Phase 3 Trial of #Semaglutide in #Metabolic Dysfunction–Associated #Steatohepatitis

In patients with #MASH and moderate or advanced #liver #fibrosis, once-weekly semaglutide at a dose of 2.4 mg improved liver steatohepatitis & fibrosis at 72 weeks
t.co/vfcgItgXpb
https://www.nejm.org/doi/full/10.1056/NEJMoa2413258
t.co
hvanspall.bsky.social
Regional disparities in participant #enrolment in RCTs are related to regional #disparities in site recruitment relative to 🌎disease distribution

We propose estimating site representation index during trial planning to ensure globally (or nationally) representative #RCT popn
doi.org/10.1002/ejhf...
hvanspall.bsky.social
#NUDGECKD #ERA25 LBT #KristofferSkaar & #TorBiering
SimPub #Circulation

Pragmatic 2x2 factorial #implementation RCT

Randomization at cluster + individual level

E-letters re #GDMT to 1540 GPs & 22617 patients w #CKD did not ⬆️ uptake of #RASi or #SGLT2i

www.ahajournals.org/doi/10.1161/...
hvanspall.bsky.social
The #sun rose
and put on a show
just for me!

#LifeOnTheLake #Sunrise #LakeMuskoka
Reposted by Harriette Van Spall MD MPH 🇨🇦
hswapnil.medsky.social
Huge Danish trial of nudges

Patient level (N 22,000)
+ practice level (1500 practice cluster with N 28,000 pts)

To increase RASination & Flozination

www.ahajournals.org/doi/abs/10.1... in @ahajournals.bsky.social at #ERA25

Absolutely null effect - is the baseline too high to improve upon?
Figure 2 Figure 5
hvanspall.bsky.social
The views are truly mesmerizing (& distracting as my office overlooks the lake and I find myself just staring at the water instead of getting work done)🙂
hvanspall.bsky.social
#Happy season is here!

#LifeOnTheLake #LakeMuskoka #Sunsets
Reposted by Harriette Van Spall MD MPH 🇨🇦
Reposted by Harriette Van Spall MD MPH 🇨🇦
womenasone.bsky.social
🚨 Missed early registration? No problem.

You can still sign up for RISE @ ESC Congress 2025, the essential event for women in cardiology.

📍 Madrid | 🗓️ Aug 28
🎯 Leadership on the Global Stage

Register now 👉 rise.womenasone.org

#LetsRISE2025 #ESCCongress #WCCardio #CardioSky #WIC
A woman sat at a table whilst having a conversation during RISE @ ESC Congress 2024. Overlain is Information about RISE @ ESC Congress 2025.
hvanspall.bsky.social
Ship of #tolerance, created by 2000 school children in our town and displayed in #OakvilleGalleries #GairlochGardens

Such a collaborative, moving art display, with ideas communicated in a way that only kids can do.
Reposted by Harriette Van Spall MD MPH 🇨🇦
citizenslobbyca.bsky.social
“The true north is indeed, strong and free”
A balanced and appropriate speech from the throne on this historical day. Climate change and biodiversity were woven into this speech alongside, not mentioning by name he who shall not be named.

m.youtube.com/watch?v=FCzk...
LIVE: King Charles presents the speech from the throne in Ottawa | CTV News Special Coverage
YouTube video by CTV News
m.youtube.com
hvanspall.bsky.social
Comrades finding new ways to rewrite history, spread disease, punish their opponents, line their pockets.. you know, business as usual
hvanspall.bsky.social
I don’t have an air fryer (have double convection ovens, which do the trick).
How did the burgers turn out?
hvanspall.bsky.social
The sweetest word
in the world,
the one I’m most grateful
to hear each day,
is #mum.

#MothersDay2025
Reposted by Harriette Van Spall MD MPH 🇨🇦