Study shows criminality is associated with damage to a key brain pathway involved in emotional control and judgment

Objective Attention-deficit/hyperactivity disorder (ADHD) has been associated with decreased regional brain volume, yet no consistent localization has emerged across studies. This discrepancy has be...

Molecular Psychiatry - White matter disconnection in acquired criminality

Background Visual mental imagery, the ability to volitionally form perceptual representations without corresponding external stimuli, allows reliving of past events, solving problems and imagining the...

Nature Reviews Neurology, Published online: 01 May 2025; doi:10.1038/s41582-025-01091-wPlasma biomarker tests for Alzheimer disease are becoming increasingly reliable, which enables implementation in clinical settings in which cerebrospinal fluid analysis and PET scans are unavailable. However, a new study shows that some patients have discordant plasma and PET biomarker results. Clinicians need clear guidance to identify and manage patients who do not fit into standard clinical or biological categories.

A Mass General Brigham study of over 9,000 participants showed that early life adversities correlate with diminished white matter connections, increasing risk for cognitive difficulties, but supportiv...

Scientists have long been aware of a paradox of neurodegenerative disease – that as the brain deteriorates, in some patients creativity flourishes. Researchers have used imaging techniques to map cre...

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.