Ben Snow Sipes
@itsbendetermined.bsky.social
PhD Candidate @ UCSF studying computational neuroscience, spectral graph theory, structure-function modeling, and what the brain does.
Teabags shown to be a significant source of microplastics. They readily enter intestine cells in vitro and even interact with cell nuclei. I wonder what percent of my body is plastic… this cannot be good.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Teabag-derived micro/nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios
The potential health implications of environmental micro/nanoplastics (MNPLs) are increasingly concerning. Beyond environmental exposure, other source…
www.sciencedirect.com
December 23, 2024 at 4:40 PM
Teabags shown to be a significant source of microplastics. They readily enter intestine cells in vitro and even interact with cell nuclei. I wonder what percent of my body is plastic… this cannot be good.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
I find it intriguing that if 10 bits/s processing speed is accurate, and microstates are approximately 0.1 seconds, then could that suggest that each microstate represents approximately 1 bit of processing? #Neuroscience
Just out in Neuron, by @jieyusz.bsky.social and @mameister4.bsky.social. Such an excellent, insightful analysis about a neuroscience paradox we don't discuss enough: The Unbearable Slowness of Being: Why do we live at 10 bits/s?
www.cell.com/neuron/abstr...
Paywall free:
arxiv.org/abs/2408.10234
The Unbearable Slowness of Being: Why do we live at 10 bits/s?
This article is about the neural conundrum behind the slowness of human behavior. The information throughput of a human being is about 10 bits/s. In comparison, our sensory systems gather data at ~10^...
arxiv.org
December 19, 2024 at 8:42 PM
I find it intriguing that if 10 bits/s processing speed is accurate, and microstates are approximately 0.1 seconds, then could that suggest that each microstate represents approximately 1 bit of processing? #Neuroscience
Reposted by Ben Snow Sipes
Reposted by Ben Snow Sipes
Nature Reviews Neuroscience
Structurally informed models of directed brain connectivity
www.nature.com/articles/s41...
Structurally informed models of directed brain connectivity
www.nature.com/articles/s41...
Structurally informed models of directed brain connectivity - Nature Reviews Neuroscience
The influence anatomy exerts on communication between brain regions remains unclear. In this Review, Greaves et al. synthesize how methods of structural connectivity integration constrain inference-ba...
www.nature.com
December 12, 2024 at 6:13 AM
Nature Reviews Neuroscience
Structurally informed models of directed brain connectivity
www.nature.com/articles/s41...
Structurally informed models of directed brain connectivity
www.nature.com/articles/s41...
Cool preprint by @misicbata.bsky.social I recall seeing an analysis like this done on social networks, so it's great to see it applied to the brain. It's getting me thinking about ways to also incorporate structural connectivity into this framework. #Neuroscience #Networks
doi.org/10.1101/2024...
doi.org/10.1101/2024...
The brain selectively allocates energy to functional brain networks under cognitive control
Network energy has been conceptualized based on structural balance theory in the physics of complex networks. We utilized this framework to assess the energy of functional brain networks under cogniti...
doi.org
December 13, 2024 at 1:25 AM
Cool preprint by @misicbata.bsky.social I recall seeing an analysis like this done on social networks, so it's great to see it applied to the brain. It's getting me thinking about ways to also incorporate structural connectivity into this framework. #Neuroscience #Networks
doi.org/10.1101/2024...
doi.org/10.1101/2024...
There are things better left unknown, and mirror organisms seem like they could be one. Pros: maybe some health applications. Cons: Entire and irreversible ecosystem disruption. It's okay for humanity not to know everything!
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report:
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
December 12, 2024 at 11:05 PM
There are things better left unknown, and mirror organisms seem like they could be one. Pros: maybe some health applications. Cons: Entire and irreversible ecosystem disruption. It's okay for humanity not to know everything!
Reposted by Ben Snow Sipes
Sometimes I think, "Compared to geological time, living things exist for only little blinks," but other times I think, "actually, life is one continuous chemical chain that first formed billions of years ago and every mountain range that existed back then has long since crumbled away to dust."
December 10, 2024 at 4:43 PM
Sometimes I think, "Compared to geological time, living things exist for only little blinks," but other times I think, "actually, life is one continuous chemical chain that first formed billions of years ago and every mountain range that existed back then has long since crumbled away to dust."
Reposted by Ben Snow Sipes
Visualizations from previous work with @rodlaje.bsky.social. The two output units in the top panel are driven by a chaotic RNN-and a small perturbation is injected at 0.16. In the lower panel the RNN is trained to "tame chaos"-creating a "dynamic attractor"-and a larger perturbation is injected.
December 2, 2024 at 4:50 AM
Visualizations from previous work with @rodlaje.bsky.social. The two output units in the top panel are driven by a chaotic RNN-and a small perturbation is injected at 0.16. In the lower panel the RNN is trained to "tame chaos"-creating a "dynamic attractor"-and a larger perturbation is injected.
I love that this article comes with graphs 👌
#Neuroscience
#Neuroscience
Huge influx of neuroscientists migrates to Bluesky
www.thetransmitter.org/community/hu...
#Neuroscience
www.thetransmitter.org/community/hu...
#Neuroscience
‘Huge influx’ of neuroscientists migrates to Bluesky
Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.
www.thetransmitter.org
November 24, 2024 at 6:28 AM
I love that this article comes with graphs 👌
#Neuroscience
#Neuroscience
Reposted by Ben Snow Sipes
Important paper!
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org
November 22, 2024 at 2:47 PM
Important paper!
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
Balancing integration and segregation is critical to brain function, and these attributes are often described by graph metrics. It turns out that structural connectome harmonics subsumes this framework by precisely extracting the integrative and segregative network features. #Neuroscience #Networks
November 22, 2024 at 5:40 PM
Balancing integration and segregation is critical to brain function, and these attributes are often described by graph metrics. It turns out that structural connectome harmonics subsumes this framework by precisely extracting the integrative and segregative network features. #Neuroscience #Networks
Love seeing this idea gain traction. Brain harmonics provides a critical framework to continue exploring degeneracy in the brain.
𝗜𝘀 𝗱𝗲𝗴𝗲𝗻𝗲𝗿𝗮𝗰𝘆 𝗼𝗻𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗯𝗲𝘀𝘁 𝗸𝗲𝗽𝘁 𝘀𝗲𝗰𝗿𝗲𝘁𝘀 𝗼𝗳 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻?
"Recurrent systems naturally implement many-to-many mappings between their units, leading to inherent plurifunctionality and many irreducible high-order mechanisms."
doi.org/10.1523/JNEU...
#neuroscience
"Recurrent systems naturally implement many-to-many mappings between their units, leading to inherent plurifunctionality and many irreducible high-order mechanisms."
doi.org/10.1523/JNEU...
#neuroscience
November 22, 2024 at 12:18 AM
Love seeing this idea gain traction. Brain harmonics provides a critical framework to continue exploring degeneracy in the brain.
Brain harmonics have Integrative, Segregative, and Degenerate regimes that have distinct properties. Degenerate harmonics have similar eigenvalues and contribute the most subject-specific network-level features. #Neuroscience #Networks #BrainFingerprinting Details in DOI: 10.1038/s42003-024-06669-6
November 21, 2024 at 8:45 PM
Brain harmonics have Integrative, Segregative, and Degenerate regimes that have distinct properties. Degenerate harmonics have similar eigenvalues and contribute the most subject-specific network-level features. #Neuroscience #Networks #BrainFingerprinting Details in DOI: 10.1038/s42003-024-06669-6
White matter harmonics are wave functions describing brain signal distributions that live on the network. I presently believe that brain harmonics are critical to understanding what the brain does. #Neuroscience #ComputationalNeuroscience #NeuroPhysics
November 20, 2024 at 5:49 PM
White matter harmonics are wave functions describing brain signal distributions that live on the network. I presently believe that brain harmonics are critical to understanding what the brain does. #Neuroscience #ComputationalNeuroscience #NeuroPhysics