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Ivano Amelio @ivanoamelio.bsky.social · 13d

Universities generate ideas and knowledge, for long-term societal progress, not short-term metrics.

"Universities are — and must continue to be — a force for good. Fresh ideas will allow the sector to thrive and deliver value for society."
@nature.com

www.nature.com/articles/d41...

Universities are — and must continue to be — a force for good

From funding squeezes to political attacks, higher education is in trouble in many parts of the world. Fresh ideas will allow the sector to thrive and deliver value for society.

www.nature.com

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Ivano Amelio @ivanoamelio.bsky.social · Sep 5

It was a fantastic Swiss Apoptosis Meeting.
Great science and nice colleagues as usual.

This time this view of the Swiss Alps from Bern to Konstanz was a plus.

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Ivano Amelio @ivanoamelio.bsky.social · Sep 1

Moonlight. Bodensee. Silence. ✨

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Ivano Amelio @ivanoamelio.bsky.social · Aug 29

⏳ Just 3 days left! Don’t miss the chance to present your science at #ECDO2025 in Berlin.

Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...

#CellDeath #Berlin2025

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Ivano Amelio @ivanoamelio.bsky.social · Aug 19

Congrats to ‪@linkermannlab.bsky.social‬ on this important work highlighting the role of sex hormones in regulating susceptibility to ferroptosis.

... and welcome on Bleusky, btw.

Andreas Linkermann @linkermannlab.bsky.social · Aug 19

Happy to start at Bluesky with a post on our recent manuscript at @nature.com:

www.nature.com/articles/s41...

Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.

Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature

17β-oestradiol establishes an anti-ferroptotic state in female kidney tubules.

www.nature.com

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Reposted by Ivano Amelio

ECDO European Cell Death Organisation @ecdoorg.bsky.social · Aug 16

Register to the ECDO-2025 in Berlin!!!

Registration is on a first come, first served basis, so we highly recommend securing your spot as soon as possible.
Join us in Berlin for an unforgettable event.

We can’t wait to welcome you to ECDO-2025! 🌍🎓

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Reposted by Ivano Amelio

Grünewald Lab @grunewaldlab.bsky.social · Aug 11

Very proud on our stellar Alina Ritter for her frist first-author paper:

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma

tinyurl.com/3kcs3bc9

@dkfz.bsky.social
@uniheidelberg.bsky.social
@nct-heidelberg.bsky.social

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Ivano Amelio @ivanoamelio.bsky.social · Aug 11

Congratulations @grunewaldlab.bsky.social team for another impressive work...

www.biorxiv.org/content/10.1...

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

Distant metastasis is the leading cause of mortality in Ewing sarcoma (EwS) -a malignant bone or soft-tissue cancer mainly affecting children, adolescents, and young adults. Despite continuous efforts...

www.biorxiv.org

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Ivano Amelio @ivanoamelio.bsky.social · Jul 19

www.science.org/doi/10.1126/...

Aberrant basal cell clonal dynamics shape early lung carcinogenesis

Preinvasive squamous lung lesions are precursors of lung squamous cell carcinoma (LUSC). The cellular events underlying lesion formation are unknown. Using a carcinogen-induced model of LUSC with no a...

www.science.org

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Ivano Amelio @ivanoamelio.bsky.social · Jul 5

"This excess word analysis suggests that at least 13.5% of 2024 abstracts were processed with LLMs. This lower bound differed across disciplines, countries, and journals, reaching 40% for some subcorpora"

www.science.org/doi/10.1126/...

Delving into LLM-assisted writing in biomedical publications through excess vocabulary

Excess words track LLM usage in biomedical publications.

www.science.org

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Reposted by Ivano Amelio

Nature @nature.com · Jul 1

Neurons often receive mitochondria from other cells, supporting cancer cell spread

https://go.nature.com/3ZLBhnV

Neuronal transfer of mitochondria to tumour cells promotes cancer spread

Neurons often receive organelles called mitochondria from other cells. It emerges that neurons donate mitochondria that support cancer-cell spread.

go.nature.com

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Reposted by Ivano Amelio

Björn Schumacher @bjornschumacher.bsky.social · Jun 19

Register now for the 7th German-French DNA Repair Meeting, which will take place at the Campus Pierre et Marie Curie of Sorbonne University in Paris, France, from 5–7 November 2025. premc.org/dnarepair202...

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Ivano Amelio @ivanoamelio.bsky.social · Jun 12

A great cell death meeting is happening in Bern, Switzerland on Sept. 4-5, 2025!

and registration is free!!!

meetings.ls2.ch/sa2m-2025

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Ivano Amelio @ivanoamelio.bsky.social · Jun 12

www.cell.com/trends/cance...

Cancer associated to low-penetrance TP53 variants: insights from p.R337H

The TP53 p.R337H variant, prevalent in Southern Brazil, is linked to variable cancer risk for pediatric and adult cancers. Unlike high-penetrance TP53 pathogenic variants, many carriers remain cancer ...

www.cell.com

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Ivano Amelio @ivanoamelio.bsky.social · Jun 1

Good Sunday!

Ivano Amelio @ivanoamelio.bsky.social · May 31

www.nature.com/articles/s41...

TurboCas for locus-specific proximity labelling - Nature Reviews Cancer

In this Tools of the Trade article, Bercin Cenik describes the development and use of TurboCas, an enzyme that pairs catalytically dead Cas9 with the proximity-labelling enzyme miniTurbo to map the re...

www.nature.com

Reposted by Ivano Amelio

Björn Schumacher @bjornschumacher.bsky.social · May 22

Register now: application deadline for the 7th 🇩🇪German-🇫🇷French 🧬DNA Repair Meeting, taking place in Paris from November 5 to 7, 2025, is fast approaching.
To submit applications and for full event details, please go to the website:
👉 lnkd.in/dfJVjYFQ

This link will take you to a page that’s not on LinkedIn

lnkd.in

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Ivano Amelio @ivanoamelio.bsky.social · May 24

"p53 status determines the epigenetic response to demethylating agents Azacitidine and Decitabine"

Nice to see this work finalised on @biorxivpreprint.bsky.social

Congrats to Matthew van de Pette @mrc-tu.bsky.social and colleagues.

www.biorxiv.org/content/10.1...

p53 status determines the epigenetic response to demethylating agents Azacitidine and Decitabine

5’-Azacitidine (Aza) and 5-Aza-2’-deoxycytidine (Dac) are widely used demethylating drugs that directly integrate into nucleic acids. They are frequently used interchangeably, surprisingly as their se...

www.biorxiv.org

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Ivano Amelio @ivanoamelio.bsky.social · May 22

Multigenerational cell tracking of DNA replication and heritable DNA damage

Congrats @altmeyerlab and collaborators

www.nature.com/articles/s41...

Multigenerational cell tracking of DNA replication and heritable DNA damage - Nature

A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may resemble early even...

www.nature.com

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Reposted by Ivano Amelio

Chris Carnie @cjcarnie.bsky.social · May 14

A PhD position is open in my group here in Heidelberg. We'll use cool primary cell models of osteosarcoma and genetic screens to understand and overcome mechanisms of clinically acquired drug resistance. It'll be a blast!

karriere.klinikum.uni-heidelberg.de/index.php?ac...

PhD position in the biology and treatment of Osteosarcoma (m/f/d)

Pflichtfelder sind mit einem (*) markiert.

karriere.klinikum.uni-heidelberg.de

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Reposted by Ivano Amelio

Barak Rotblat @barakrotblat.bsky.social · May 10

aligning identity is a challenge 👇

Christian Frezza @frezzalab.bsky.social · May 9

I'd like to share this short piece on a topic I hope you will find useful. It is the result of a personl journey and many discussions with friends and peers. Let me know your thoughts.

network.febs.org/posts/the-pr...

The Professional Self: The Enemy Inside

network.febs.org

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Ivano Amelio @ivanoamelio.bsky.social · May 11

"The search for worth is endless because the benchmarks by which we are measured are constantly changing; it is a moving target."

I completely agree, it is a losing battle. And often, the criteria are also subjective.

Thank you, Christian, for sharing such a beautiful piece.

Christian Frezza @frezzalab.bsky.social · May 9

I'd like to share this short piece on a topic I hope you will find useful. It is the result of a personl journey and many discussions with friends and peers. Let me know your thoughts.

network.febs.org/posts/the-pr...

The Professional Self: The Enemy Inside

network.febs.org

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Ivano Amelio @ivanoamelio.bsky.social · May 9

www.science.org/doi/10.1126/...

Integrating exposomics into biomedicine

Assessing a full range of environmental exposures will improve human health

www.science.org

Reposted by Ivano Amelio

@vdangioE3lab @vdangioe3lab.bsky.social · May 7

🧬 New Research Alert! 🧬

"Pervasive phenotypic effects of FBXO42 controlled by regulation of PP4 phosphatase"
www.biorxiv.org/content/10.1...
Our findings reveal that Fbxo42 main function is to control PP4 phosphatase.
Discussions are highly welcome!
#bioRxiv #Research #Science #ubiquitin

Pervasive phenotypic effects of FBXO42 controlled by regulation of PP4 phosphatase

F-box proteins are the substrate recognition modules of the SCF (SKP1–Cullin– F-box) E3 ubiquitin ligase complex. FBXO42, an understudied member of this family, has recently emerged as a modulator of ...

www.biorxiv.org

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Ivano Amelio @ivanoamelio.bsky.social · May 8

... yes, but of course I am right!

www.nature.com/articles/d41...

Make science more collegial: why the time for ‘adversarial collaboration’ has come

Bringing together proponents of rival theories to test their ideas against each other can advance science — but only if all sides can accept that they might be wrong.

www.nature.com