jaebcenter.bsky.social
@jaebcenter.bsky.social
Primary results from the INHALE-1 study examining inhaled insulin use in children with #T1D were published in November! diabetesjournals.org/care/article...
INHALE-1: A Multicenter Randomized Trial of Inhaled Technosphere Insulin in Children With Type 1 Diabetes
OBJECTIVE. To evaluate inhaled technosphere insulin (TI) in children with diabetes.RESEARCH DESIGN AND METHODS. 230 youth 4–17 years old with type 1 (98%)
diabetesjournals.org
December 2, 2025 at 4:10 PM
We are excited to share a unique opportunity for adults aged 18 and up living with type 1 diabetes to join an online diabetes and exercise education research study. To learn more and to see if you may be eligible, click here: www.jaeb.org/edge/
November 26, 2025 at 3:26 PM
Dr. Camille Powe stopped by the Diabetes Nerd podcast to discuss pregnancy and diabetes and the T1D Pregnancy & Me study in October, give it a watch/listen! www.youtube.com/watch?v=odmS...
Pregnancy & Type 1 Diabetes: What Every Woman Should Know
YouTube video by Diabetes Nerd
www.youtube.com
November 24, 2025 at 5:11 PM
If you are in Montreal for ISPAD this weekend, swing through the poster display to check out the extended study results from INHALE-1, poster P-653!

ispad2025.abstractserver.com/program/#/de...
Program
ispad2025.abstractserver.com
November 6, 2025 at 5:12 PM
JCHR was pretty active at NACFC last week in Seattle with baseline data from the STRONG study being presented and investigator meetings for the SPeCTRuM and BP CFRD studies, looking good team!
October 30, 2025 at 2:13 PM
We are proud to highlight our founder Dr. Roy Beck was a guest of honor at the recent American Academy of Ophthalmology meeting last week! www.aao.org/eyenet/acade...
Meet the 2025 Presidential Guests
Academy President Michael X. Repka, MD, MBA, began introduces three of her treasured colleagues: Roy W. Beck, MD, PhD; John M. Haley, MD; and David L. Guyton, MD.
www.aao.org
October 23, 2025 at 3:28 PM
A huge THANK YOU to our incredible investigators and staff from MGH and Joslin for joining the Breakthrough T1D Walk and sharing information about the T1D Pregnancy & Me Study with the community. Your dedication truly makes a difference. Together, we’re moving closer to breakthroughs that matter!
October 9, 2025 at 2:31 PM
Dr. Camille Powe and Carrie Matuzsan sat down with Stacey Simms on the Diabetes Connection podcast to discuss the T1D Pregnancy Study, give it a listen!

diabetes-connections.com/t1d-pregnanc...
T1D pregnancies deserve better research: this study targets the gaps - Diabetes Connections
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diabetes-connections.com
September 17, 2025 at 1:34 PM
Reposted
Michael Welsh of the University of Iowa, a winner of the @laskerfdn.bsky.social Clinical Medical Research Award, reflects on his decades of work unraveling #CysticFibrosis and how new therapies have transformed patients’ lives.

#Lasker2025 #LaskerAward
How Cystic Fibrosis Went From Fatal to Treatable
This Medical News article is an interview with pulmonologist Michael Welsh, MD, the co-recipient of the 2025 Lasker-DeBakey Clinical Medical Research Award for his research on cystic fibrosis.
jamanetwork.com
September 11, 2025 at 2:19 PM
Back in July, Dr. Carol Levy sat down on Diabetes Dialogue to discuss the T1D Pregnancy and Me study, stay tuned for additional updates!

www.hcplive.com/view/diabete...
Diabetes Dialogue: Updates in Type 1 Diabetes and Pregnancy with Carol Levy, MD
Isaacs, Bellini, and Levy discuss a currently recruiting trial investigating CGM metrics in pregnant individuals with type 1 diabetes.
www.hcplive.com
September 9, 2025 at 5:30 PM
Earlier this year results from the TIGHT study on the use of Dexcom G7 CGMs in the ICU came out in Diabetes Technology & Therapeutics and now the Dexcom G6 Pro results are available!

www.liebertpub.com/doi/10.1177/...
Accuracy of Dexcom G6 Pro Continuous Glucose Monitor in the Intensive Care Setting: TIGHT ICU G6 Study | Diabetes Technology & Therapeutics
Objective: To evaluate the accuracy of the Dexcom G6 Pro continuous glucose monitoring (CGM) system in the intensive care unit (ICU) setting. Methods: We performed a prospective, observational, multicenter study in adult ICU patients with a known diagnosis of diabetes or stress hyperglycemia who were being treated with insulin. Two Dexcom G6 Pro sensors were placed. Sensor accuracy was assessed by pairing sensor and blood glucose (BG) measurements obtained as a part of usual ICU care. Accuracy of the G6 Pro also was assessed concurrently in non-ICU hospitalized individuals. Results: A total of 130 participants were enrolled, with mean (±SD) age of 62 ± 12 years, and preexisting diabetes was present in 73% and stress hyperglycemia in 27%. A total of 9120 sensor-BG pairs were analyzed. The mean relative absolute difference (RAD) was 23% (median 19%), with a mean difference of +25 mg/dL (median 25 mg/dL). Forty-one percent of sensor glucose values were within 15% of BG values for BG values ≥100 mg/dL or within 15 mg/dL of BG values for BG values <100 mg/dL, 53% within 20%/20 mg/dL, and 72% within 30%/30 mg/dL. For the two sensors worn simultaneously, the mean absolute difference was 24 mg/dL (median 19 mg/dL) and the mean RAD was 14% (median 11%). In the non-ICU setting (N = 60; 1318 sensor-BG pairs), the mean difference was 24 mg/dL (median 21 mg/dL) and the mean RAD was 21% (median 17%). Conclusions: Accuracy of the Dexcom G6 Pro sensor in the ICU setting was worse than has previously been reported for this sensor, with sensor values tending to be biased high. However, this appears to be a function of the G6 Pro sensor and not the setting as similar results were obtained in a non-ICU setting. Results should not be generalized to the real-time G6 or other sensors.
www.liebertpub.com
September 8, 2025 at 1:56 PM
Earlier in the year JCHR and The Leona M. and Harry B. Helmsley Charitable Trust were excited to announce the start of the T1D Pregnancy & Me study. A more detailed explanation is available from Drug Delivery!

www.drugdeliverybusiness.com/researchers-...
Researchers look to study AID in pregnant women with diabetes
Researchers and diabetes in pregnancy investigators say they opened an observational study of automated insulin delivery (AID) in pregnancy.
www.drugdeliverybusiness.com
August 20, 2025 at 7:01 PM
The most recent work from PEDIG was published in late July in the Journal of the American Association for Pediatric Ophthalmology and Strabismus!

www.sciencedirect.com/science/arti...
Ophthalmic outcomes five years after lensectomy among children with Down syndrome
www.sciencedirect.com
August 6, 2025 at 1:05 PM
One of the most cited research projects here at Jaeb in the last 10 years was the T1D Exchange Clinic Network. This deep dive into the data from 2015 is still a treasure trove of information!

diabetesjournals.org/care/article...
Current State of Type 1 Diabetes Treatment in the U.S.: Updated Data From the T1D Exchange Clinic Registry
To examine the overall state of metabolic control and current use of advanced diabetes technologies in the U.S., we report recent data collected on individ
diabetesjournals.org
July 24, 2025 at 2:47 PM
The most recent results from the Foundation Fighting Blindness Clinical Consortium were published in February in IVOS!

iovs.arvojournals.org/article.aspx...
Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll | IOVS | ARVO Journals
iovs.arvojournals.org
July 21, 2025 at 2:22 PM
The latest results from the CLVer study were published in Diabetes Care earlier this month!

diabetesjournals.org/care/article...
Associations of CGM Metrics With Stimulated C-Peptide Measures in Youth With Recent-Onset Type 1 Diabetes
OBJECTIVE. Continuous glucose monitoring (CGM) measures could be a surrogate for stimulated C-peptide outcomes in type 1 diabetes trials.RESEARCH DESIGN AN
diabetesjournals.org
June 27, 2025 at 1:27 PM
We're excited to announce the recent launch of the T1D Pregnancy & Me study with The Leona M. and Harry B. Helmsley Charitable trust!

helmsleytrust.org/news-and-ins...
Launch of Innovative Real-World Study on Automated Insulin Delivery in Type 1 Diabetes During Pregnancy - Helmsley Charitable Trust
helmsleytrust.org
June 9, 2025 at 8:04 PM
The latest data from the TIGHT study examining the use of CGMs in the ICU setting were published in Diabetes Technology & Therapeutics!

www.liebertpub.com/doi/abs/10.1...
Dexcom G7 Accuracy and Reproducibility in the Intensive Care Unit | Diabetes Technology & Therapeutics
Objective: To evaluate the accuracy of Dexcom G7 continuous glucose monitor (CGM) in the intensive care unit (ICU) setting. Methods: We performed a prospective, single-center study in patients with kn...
www.liebertpub.com
June 4, 2025 at 5:58 PM
PEDIG is another of our long running registries providing doctors with a collaborative network to help develop and run multicenter clinical research in eye disorders that affect children. For more info on specific studies and results visit the website! public.jaeb.org/pedig/view/H...
Pediatric Eye Disease Investigator Group - Public Site
public.jaeb.org
May 12, 2025 at 4:30 PM
Reposted
Automated Insulin Delivery in Type 2 Diabetes (2IQP trial) nej.md/4ioCwR2

Lorundrostat for Uncontrolled Hypertension (Advance-HTN trial) nej.md/4ipbCIf

Enhanced CAR T-Cell Therapy for Lymphoma nej.md/4jSiXkX

Subscribe to NEJM for the latest medical research: nej.md/subscribe
May 8, 2025 at 1:09 PM
The latest results from our Foundation Fighting Blindness (FFB) consortium were published earlier this year in IOVS!
iovs.arvojournals.org/article.aspx...
Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll | IOVS | ARVO Journals
iovs.arvojournals.org
May 7, 2025 at 1:24 PM