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James Gurney @jamesgurney.bsky.social · 3d

Household energy after submitting grant this week.

Reposted by James Gurney

Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 8d

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production

Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces

www.gla.ac.uk/postgraduate...

please repost

University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Paul A Hoskisson

www.gla.ac.uk

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Reposted by James Gurney

Ákos T Kovács @evolvedbiofilm.bsky.social · 10d

PhD fellowship in biofilm-phage interactions - with Mette Burmølle at University of Copenhagen 🇩🇰
deadline 1 October 2025

employment.ku.dk/faculty?show...

#phagesky #microsky

PhD fellowship in biofilm-phage interactions

employment.ku.dk

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Reposted by James Gurney

Carolyn Ibberson @cbibberson.bsky.social · 21d

Come join us in Knoxville! 🧫🧪🦠

utkmicrobiology.bsky.social @utkmicrobiology.bsky.social · 22d

We’re hiring a tenure-track Assistant Professor in Microbial Drivers of Chronic Disease, starting Fall 2026!

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Reposted by James Gurney

Michael Brockhurst @brockhurstlab.bsky.social · 13d

Recent paper from the lab studying predictors of phage cocktail efficacy against complex clinical Pseudomonas populations

royalsocietypublishing.org/doi/epdf/10....

Led by Rosanna Wright with extraordinary MSc (PhD) student Maisie Czernuska

Bacteria–phage infection network structure and genomic defence system content predict efficacy of a phage therapy cocktail against Pseudomonas aeruginosa from chronic lung infections

royalsocietypublishing.org

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Reposted by James Gurney

Ajai Dandekar @ajaidandekar.bsky.social · Sep 6

Andrew Frando, @jrchandler.bsky.social, and I wrote a primer about excellent work done in Sam Brown's group @brownlab.bsky.social

journals.plos.org/plosbiology/...

Better together: Reciprocal activation of quorum sensing circuits enhances bacterial communication

Many bacteria use quorum sensing to control gene transcription based on population density. This primer explores a recent study in PLOS Biology which found that in Pseudomonas aeruginosa, two quorum-s...

journals.plos.org

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Reposted by James Gurney

PLOS Biology @plosbiology.org · Sep 5

Bacterial #QuorumSensing is often assumed to follow a strict hierarchy. @brownlab.bsky.social &co find that #Pseudomonas aeruginosa instead uses a reciprocal, cooperative system that enhances responsiveness to population density & environmental changes @plosbiology.org 🧪 plos.io/3I7DhRG

The las and rhl QS systems have a reciprocal, synergistic, and unequal relationship. Top: Single-signal models demonstrate that the summed effects of single signals (3 oxo C12 HSL alone, red; C4 HSL alone, orange) cannot account for the maximal expression of lasI or rhlI. The upper green, flat surfaces in the plots indicate the maximum mean expression level measured across all combinations of signal concentrations while the lower semi-transparent surfaces mark the sum of single signal effects. The plotted points represent observed expression levels when C4 HSL is withheld (red) and when 3 oxo C12 HSL is withheld (yellow). Lines indicate the model predictions. Bottom: Multi-signal non-linear models capture the synergistic effects of both signals and match observed expression levels. Model estimates are shown as grid lines. Horizontal bars show the mean value of expression observed at each combination of signal concentrations. Lines extend from these mean values to the relevant grid point for clarity. Right: Data show that relationship of the las and rhl systems is reciprocal, and the multi-signal model quantifies the strength of those interactions. In particular, it reveals the contribution of both signals to the maximum fold-change in expression of both synthases. The charts in this panel summarize the contribution of 3 oxo C12 HSL (red), C4 HSL (yellow), and the synergistic combination of both (orange).

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James Gurney @jamesgurney.bsky.social · Sep 5

Standing room only for Eli Mehlferber from @brownbio.bsky.social for breakfast talk this morning. Giving a great talk.

James Gurney @jamesgurney.bsky.social · Sep 3

queen elizabeth is wearing a blue suit and pearls .

ALT: queen elizabeth is wearing a blue suit and pearls .

media.tenor.com

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James Gurney @jamesgurney.bsky.social · Sep 3

a man is sitting at a desk with a panda bear on his shoulders

ALT: a man is sitting at a desk with a panda bear on his shoulders

media.tenor.com

James Gurney @jamesgurney.bsky.social · Sep 3

WHAT?!? one way to cut off my last connection to the UK. Since when has the BBC News become subscription based?

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Reposted by James Gurney

Mya Breitbart @viromegirl.bsky.social · Aug 1

Do you love phage? I have an opening for a postdoc in my lab at the University of South Florida College of Marine Science (@cmarinescience.bsky.social) looking at interactions between marine phage and iron, which is an important limiting trace metal in the oceans (1/5) 🧵#phagesky 🦠🌊

Electron micrograph of two phage infecting a host cell side-by-side, with hearts between them

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James Gurney @jamesgurney.bsky.social · Aug 17

~3 inch Joro Spider. Invasive species in Georgia now.

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James Gurney @jamesgurney.bsky.social · Aug 16

New foster in the house. “Lovely” she fits her name to a tee. If you know anyone looking for a dog in the Atlanta area hit me up!

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James Gurney @jamesgurney.bsky.social · Aug 16

This is what the look of betrayal from a cat looks like.

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Reposted by James Gurney

Ellinor Alseth @ellinoralseth.bsky.social · Aug 8

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway

Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

www.jobbnorge.no

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James Gurney @jamesgurney.bsky.social · Aug 7

Very proud of my three wonderful Summer undergrad research fellows, all supported by the Molecular Basis for Disease program at State. All three have done great work and have been a pleasure to have in the lab.

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James Gurney @jamesgurney.bsky.social · Jul 31

I'd love to come. We have two projects that are ready for public consumption. CRISPRcas and salt. we combined bioinformatics and wet work to explain why archaea have a higher prevalence of Cas. 2nd single cell RNA seq under phage infection. Also happy to talk about outreach and work with Kurzgesagt.

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James Gurney @jamesgurney.bsky.social · Jul 28

Finally got my iPod touch to turn back on. I bought this with my first PhD pay check. Time to listen to some classic pre 2010 tunes.

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James Gurney @jamesgurney.bsky.social · Jul 18

That climb yesterday was something else.

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James Gurney @jamesgurney.bsky.social · Jul 18

Used AI to recreate the strangest bathroom I viewed when I was trying to find an apartment in France. This is a fairly close rendering. Including the off angle steps and it being in the center of the room. It was a bizarre death trap. Just the right height if you fell you’d break your neck.

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James Gurney @jamesgurney.bsky.social · Jul 12

New lab logo

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Reposted by James Gurney

Gina Lewin @ginalewin.bsky.social · Jul 11

Lovely time with new and old friends at microbiology population biology camp. Leaving with lots of new ideas (and lots of new bug bites)

@cbibberson.bsky.social @peachypotato.bsky.social @jamesgurney.bsky.social

College of New Hampshire views and people eating lobster

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Reposted by James Gurney

Carolyn Ibberson @cbibberson.bsky.social · Jul 11

Feeling tired but inspired after a great week at the #MicrobialPopBioGRC. Great to see old friends and make some new ones! 🦞🗻🧫

@ginalewin.bsky.social @peachypotato.bsky.social @jamesgurney.bsky.social @stephenkdolan.bsky.social

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James Gurney @jamesgurney.bsky.social · Jul 10

My first GRC and I get why this is so many folks favorite meeting. Great presentations and interaction with some many people.

Only gripe is my room was hot. But it also does this! Warning flashing lights!

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