Jay Joseph
@jayjoseph22.bsky.social
Psychologist/author deconstructing behavioral/psychiatric genetic research and theories. Author of "Schizophrenia and Genetics: The End of An Illusion" (2023). https://jayjoseph22.substack.com/
Pinned
Jay Joseph
@jayjoseph22.bsky.social
· Aug 30
The 110-Year “Schizophrenia Genetic Research” Train Wreck
The “genetics of schizophrenia” area of research—which began as a eugenics program—is currently in disaster mode and awaits its endpoint.
www.madinamerica.com
My new article: “The 110-Year ‘Schizophrenia Genetic Research’ Train Wreck.”
"The schizophrenia/psychosis causality puzzle pieces will fit together much better once we knock the ‘genetics’ pieces off the table.”
www.madinamerica.com/2025/08/the-...
"The schizophrenia/psychosis causality puzzle pieces will fit together much better once we knock the ‘genetics’ pieces off the table.”
www.madinamerica.com/2025/08/the-...
Any honest HBD race scientists out there? No one gets "canceled" for saying "IQ is above 0% heritable." That's Psychology 101. Claims in favor of genetic ethnic differences in IQ are another matter. HBDers knowingly conflate within- and between-group IQ genetic claims to hoodwink their audience.
November 25, 2025 at 4:08 PM
Any honest HBD race scientists out there? No one gets "canceled" for saying "IQ is above 0% heritable." That's Psychology 101. Claims in favor of genetic ethnic differences in IQ are another matter. HBDers knowingly conflate within- and between-group IQ genetic claims to hoodwink their audience.
A fascinating aspect of social media is that someone who blocked you years ago, and continues to block, can talk about something you supposedly "told" him about IQ prediction ("prediction" = correlation, not cause).
November 23, 2025 at 6:18 PM
A fascinating aspect of social media is that someone who blocked you years ago, and continues to block, can talk about something you supposedly "told" him about IQ prediction ("prediction" = correlation, not cause).
Reposted by Jay Joseph
So there you have it, twin study estimates were greatly inflated, and molecular data sets the record straight. I walk through possible counter-arguments, but ultimately the uncomfortable truth is that genes contribute to traits much less than we always thought.
November 21, 2025 at 10:34 PM
So there you have it, twin study estimates were greatly inflated, and molecular data sets the record straight. I walk through possible counter-arguments, but ultimately the uncomfortable truth is that genes contribute to traits much less than we always thought.
Reposted by Jay Joseph
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
Reposted by Jay Joseph
🧬 Let’s do a GWAS on zip code. Say, the first two digits are 70 (my choice). You will likely get some correlations if the sample is large enough. What percentage of the variance explained will you get for the SNPs for “70” zip code? Say it’s 10% even with your PCA’s. Is “70” zip code genetic? Now…
November 18, 2025 at 9:19 PM
🧬 Let’s do a GWAS on zip code. Say, the first two digits are 70 (my choice). You will likely get some correlations if the sample is large enough. What percentage of the variance explained will you get for the SNPs for “70” zip code? Say it’s 10% even with your PCA’s. Is “70” zip code genetic? Now…
Reposted by Jay Joseph
Eugenics is described as a “science” which “derives from the fundamental biological reality that many human traits, including cognitive ability, physical health, and behavioral dispositions, possess substantial genetic components”
White nationalist talking points and racial pseudoscience: welcome to Elon Musk’s Grokipedia www.theguardian.com/technology/2...
White nationalist talking points and racial pseudoscience: welcome to Elon Musk’s Grokipedia
World’s richest person wanted to ‘purge’ propaganda from Wikipedia, so he created a compendium of racist disinformation
www.theguardian.com
November 18, 2025 at 12:15 AM
Eugenics is described as a “science” which “derives from the fundamental biological reality that many human traits, including cognitive ability, physical health, and behavioral dispositions, possess substantial genetic components”
Reposted by Jay Joseph
I talked a bit with Jason about Grokipedia and it is, without exaggeration, like if you trained an LLM solely on white supremacist blogs and had it try to write Wikipedia entries. Some of the most insane stuff I’ve seen on the internet
Hard to find a clearer distillation of the gen ai project.
White nationalist talking points and racial pseudoscience: welcome to Elon Musk’s Grokipedia
World’s richest person wanted to ‘purge’ propaganda from Wikipedia, so he created a compendium of racist disinformation
www.theguardian.com
November 17, 2025 at 7:08 PM
I talked a bit with Jason about Grokipedia and it is, without exaggeration, like if you trained an LLM solely on white supremacist blogs and had it try to write Wikipedia entries. Some of the most insane stuff I’ve seen on the internet
In an ironic historical twist, the criminal behavior of two German men may have been influenced by "syndromes" associated with each other's names.
November 13, 2025 at 4:50 PM
In an ironic historical twist, the criminal behavior of two German men may have been influenced by "syndromes" associated with each other's names.
Reposted by Jay Joseph
As of this morning, Starbucks workers across the country are officially ON STRIKE. And we're prepared for this to become the biggest and longest ULP strike in Starbucks history.
Say #NoContractNoCoffee with us: DON'T BUY STARBUCKS for the duration of our open-ended ULP strike! $SBUX
Say #NoContractNoCoffee with us: DON'T BUY STARBUCKS for the duration of our open-ended ULP strike! $SBUX
November 13, 2025 at 11:33 AM
As of this morning, Starbucks workers across the country are officially ON STRIKE. And we're prepared for this to become the biggest and longest ULP strike in Starbucks history.
Say #NoContractNoCoffee with us: DON'T BUY STARBUCKS for the duration of our open-ended ULP strike! $SBUX
Say #NoContractNoCoffee with us: DON'T BUY STARBUCKS for the duration of our open-ended ULP strike! $SBUX
Reposted by Jay Joseph
This paper clearly exposes the hereditarian project for the pseudoscience it is 👇 Also highlights how overtly political are those who promote the claim there are evolved racial differences in cognitive and behavioural traits, despite strong protestations to the contrary
Today is the day! Our reply to the two concurrent critiques (from the same set of authors) is now published in the journal Intelligence 🧵 1/
November 12, 2025 at 4:13 PM
This paper clearly exposes the hereditarian project for the pseudoscience it is 👇 Also highlights how overtly political are those who promote the claim there are evolved racial differences in cognitive and behavioural traits, despite strong protestations to the contrary
Ironic he had "Kallmann Syndrome." FJ Kallmann was a fanatical racial hygienist and schizophrenia family/twin researcher during the Third Reich. He advocated forcibly sterilizing German "schizophrenic taint carriers" and some of their relatives. Had to leave Germany in 1936 due to Jewish ancestry.
November 12, 2025 at 8:28 PM
Ironic he had "Kallmann Syndrome." FJ Kallmann was a fanatical racial hygienist and schizophrenia family/twin researcher during the Third Reich. He advocated forcibly sterilizing German "schizophrenic taint carriers" and some of their relatives. Had to leave Germany in 1936 due to Jewish ancestry.
Reposted by Jay Joseph
Today is the day! Our reply to the two concurrent critiques (from the same set of authors) is now published in the journal Intelligence 🧵 1/
November 12, 2025 at 3:31 PM
Today is the day! Our reply to the two concurrent critiques (from the same set of authors) is now published in the journal Intelligence 🧵 1/
For those interested in the eugenic origins of the field of Psychiatric Genetics, check out this Google AI description of a 1942 German-language article written by Ernst Rüdin, the field's undisputed founding father.
www.google.com/search?q=R%C...
www.google.com/search?q=R%C...
Google Search
www.google.com
October 19, 2025 at 11:45 PM
For those interested in the eugenic origins of the field of Psychiatric Genetics, check out this Google AI description of a 1942 German-language article written by Ernst Rüdin, the field's undisputed founding father.
www.google.com/search?q=R%C...
www.google.com/search?q=R%C...
Wow. Who is this "blank slate Lysenkoist"? Any guesses?
October 17, 2025 at 6:16 PM
Wow. Who is this "blank slate Lysenkoist"? Any guesses?
Reposted by Jay Joseph
Adam Urato and Joanna Moncrieff join us on the Mad in America #podcast to discuss potential harms caused by #antidepressant use during pregnancy.
#mentalhealth #psychology #psychiatry #pregnancyhealth #maternity #FDA
Read or listen here ⬇️
#mentalhealth #psychology #psychiatry #pregnancyhealth #maternity #FDA
Read or listen here ⬇️
Medical Organizations Turn Blind Eye to Harms of Maternal Antidepressant Use: A Conversation With Adam Urato and Joanna Moncrieff
Adam Urato and Joanna Moncrieff join Robert Whitaker on the Mad in America podcast to discuss risks posed by maternal use of antidepressants.
buff.ly
October 16, 2025 at 4:04 PM
Adam Urato and Joanna Moncrieff join us on the Mad in America #podcast to discuss potential harms caused by #antidepressant use during pregnancy.
#mentalhealth #psychology #psychiatry #pregnancyhealth #maternity #FDA
Read or listen here ⬇️
#mentalhealth #psychology #psychiatry #pregnancyhealth #maternity #FDA
Read or listen here ⬇️
Really? Systematic racism is built into IQ tests, which are designed to produce ethnic but not gender differences. Murray and Pinker assume ethnic differences are influenced by genetics, when there is no scientifically valid evidence supporting even WITHIN-group "heritability" osf.io/preprints/ps...
October 15, 2025 at 3:07 PM
Really? Systematic racism is built into IQ tests, which are designed to produce ethnic but not gender differences. Murray and Pinker assume ethnic differences are influenced by genetics, when there is no scientifically valid evidence supporting even WITHIN-group "heritability" osf.io/preprints/ps...
It can’t be stressed enough that, false genetic between-group difference claims aside, The Bell Curve presented no scientifically valid evidence in support of genetic influences on within-group IQ score differences.
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Your Genes Are Simply Not Enough to Explain How Smart You Are
Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.
www.theatlantic.com
October 13, 2025 at 4:31 PM
It can’t be stressed enough that, false genetic between-group difference claims aside, The Bell Curve presented no scientifically valid evidence in support of genetic influences on within-group IQ score differences.
Reposted by Jay Joseph
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Your Genes Are Simply Not Enough to Explain How Smart You Are
Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.
www.theatlantic.com
October 13, 2025 at 1:33 PM
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Reposted by Jay Joseph
I’ve shared these a few times on the other site, but since everything is new again, here’s a thread of extremist profiles on prominent scientific racists I wrote for @SPLC roughly 10 years ago:
July 5, 2023 at 4:42 PM
I’ve shared these a few times on the other site, but since everything is new again, here’s a thread of extremist profiles on prominent scientific racists I wrote for @SPLC roughly 10 years ago:
The decades-old Danish schizophrenia adoption studies by Seymour Kety and colleagues are still widely cited. Yet, the genetic findings from these studies were based on deceptive (p-hacked) research practices. My latest detailed description of one aspect of this deception.
jayjoseph22.substack.com
jayjoseph22.substack.com
October 5, 2025 at 2:51 PM
The decades-old Danish schizophrenia adoption studies by Seymour Kety and colleagues are still widely cited. Yet, the genetic findings from these studies were based on deceptive (p-hacked) research practices. My latest detailed description of one aspect of this deception.
jayjoseph22.substack.com
jayjoseph22.substack.com
Reposted by Jay Joseph
Over 2 million people across Italy have rallied in more than 100 cities for a one-day general strike.
2 million rally in Italy for Gaza as general strike halts key services
Over 2 million people across Italy have rallied in more than 100 cities for a one-day general strike.
bit.ly
October 4, 2025 at 9:00 AM
Over 2 million people across Italy have rallied in more than 100 cities for a one-day general strike.
Reposted by Jay Joseph
The world against complicity!
October 2, 2025 at 1:10 PM
The world against complicity!
The causes of autism are in the news these days. In my 2006 book "The Missing Gene," I assessed the evidence that autism has a genetic basis. The evidence usually cited came from twin and DNA-based research. I concluded that the genetic evidence was weak. Chapters:
drive.google.com/file/d/1voc_...
drive.google.com/file/d/1voc_...
September 25, 2025 at 6:41 PM
The causes of autism are in the news these days. In my 2006 book "The Missing Gene," I assessed the evidence that autism has a genetic basis. The evidence usually cited came from twin and DNA-based research. I concluded that the genetic evidence was weak. Chapters:
drive.google.com/file/d/1voc_...
drive.google.com/file/d/1voc_...