Jeff Bush
@jeffbush.bsky.social
140 followers 210 following 10 posts
Developmental geneticist who studies the cellular basis of mammalian morphogenesis and how it goes wrong in congenital disease.
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jeffbush.bsky.social
This is awesome! Looking forward to reading it.
jeffbush.bsky.social
Nice! Congratulations Jeremy, Roman, Andrei, and everyone!
jeffbush.bsky.social
devbiol.bsky.social
#DBfeature 🐣

CRISPR-Cas13d enables targeted gene expression knockdown in chick embryos, expanding the experimental potential and versatility of this model system.

by Minyoung Kim and Erica Hutchins @drericabiophd.bsky.social

www.sciencedirect.com/science/arti...

#CRISPRCas #ChickEmbryo
Cross-section of HH9 chick embryo head showing reduced PAX7 signal on CRISPR-Cas13d knockdown side (~17% decrease, n=15), highlighted in GFP+ cells.
Reposted by Jeff Bush
ctbatucsf.bsky.social
Karin Shamardani, DDS/PhD candidate, is working with Jeff Bush @jeffbush.bsky.social to study how Efnb1 and the understudied actin-regulator gene Shrm4 interact to control palatal outgrowth and mesenchymal organization during craniofacial development.
Reposted by Jeff Bush
semilc.bsky.social
I'm thrilled to announce that my lab is opening this August in the Department of Cell & Tissue Biology @ UCSF!

We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
Circular lab logo consisting of a ball of cells labeled with cyan nuclei and red cilia, surrounded by a white circle and the text Choksi Lab and UCSF. The 'o' in Choksi is a schematic of a multiciliated cell.
Reposted by Jeff Bush
ctbatucsf.bsky.social
CTB welcomes new Assistant Professor Semil Choksi @semilc.bsky.social to the department! The Choksi Lab will study how airway stem cells generate multiciliated cells - and how this process goes wrong in respiratory disease. His lab is opening this August. Visit choksilab.org to learn more!
jeffbush.bsky.social
We’re so lucky you will join us Semil! Can’t wait!
jeffbush.bsky.social
Just recruited two more grad students to be appreciated on Bluesky! @jasminegarciia.bsky.social @davidsungtooth.bsky.social @ophirklein.bsky.social
jeffbush.bsky.social
Happy graduate student appreciation week to David Sung and Luke Lucido!…also trying to encourage them to join Bluesky
jeffbush.bsky.social
Congratulations to Camilla Teng, for winning the "Platform presentation SDB prize" for post-docs at the Northwest SDB meeting, which sounds like it was a fantastic meeting! Camilla will be on the faculty job market soon, so look out for her! @socdevbio.bsky.social @ctbatucsf.bsky.social
Reposted by Jeff Bush
nature.com
Nature @nature.com · Feb 20
A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.

https://go.nature.com/41a7Zzj
Rare genetic disorder treated in womb for the first time
The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.
go.nature.com
Reposted by Jeff Bush
sethblackshaw.bsky.social
To my friends and colleagues at UAB, IU, UF, FSU, UL, WashU, OSU, CWRU, etc, etc. Call both your senators and your representative. They listen. Emphasize the direct economic impact of NIH research, and the indirect impacts on pharmaceutical/biotech. Underscore its relevance to national security.
adrianna.bsky.social
The Senate HELP Committee has jurisdiction over NIH.

GOP members of the committee represent AK, AL, IN, FL, KS, KY, LA, ME, MO, OH, and SC.

Research universities and hospitals in those states need to be extra loud.
jeffbush.bsky.social
Great new lab opening!…
rkzwick.bsky.social
The Zwick lab has landed in the Regenerative Medicine Institute @NYU! I’m incredibly excited to build a team to study how epithelial organs are patterned and remodeled throughout life, with a major focus on the remarkable changes that occur in the maternal body during pregnancy..1/5
Reposted by Jeff Bush
ctbatucsf.bsky.social
Vahid Niknezhad joined the Knox lab in 2022 as a postdoctoral scholar, focusing on the development of biomaterials and hydrogels for drug delivery systems and tissue repair technologies. #ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
ctbatucsf.bsky.social
Helen, a postdoc in the Hutchins lab @drericabiophd.bsky.social, is interested in how RNA binding proteins and modifications contribute to the dynamic process of neural crest cell development, and is also passionate about laboratory waste reduction and scientific illustration.#ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
ctbatucsf.bsky.social
Petria-George Thompson, a postdoc in the Goga lab @andreigoga.bsky.social, is studying mechanisms of CDK2 inhibition as therapeutics for breast cancer and other cancers. #ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
ctbatucsf.bsky.social
Camilla Teng in the Bush lab @jeffbushman.bsky.social is working to understand cell behaviors and force generators driving development of the upper lip. This mysterious process has relevance to cleft lip, which is the most common congenital anomaly affecting the face. #ucsfNPAW #UCSFpostdocs