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Andrei Goga

@andreigoga.bsky.social

2.5K followers 1.1K following 110 posts

Professor, UCSF Dept Cell & Tissue Biology and Medicine / Oncology Breast Medical Oncologist and Cell Biology. Exploring new mechanisms of cancer biology & therapeutics. Views my own. 🧪 #medsky Oncogenes.net

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Andrei Goga @andreigoga.bsky.social · Nov 14

Introducing the Goga Lab @ctbatucsf.bsky.social @ucsfcancer.bsky.social

We study aggressive breast and liver cancers and mechanisms of oncogene signaling that lead to metastasis.
Our works spans various areas including metabolism, cell cycle and spatial organization of tumors.

oncogenes.net

Goga Lab members dressed up as characters from The Office (circa October 31, 2023)

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Andrei Goga @andreigoga.bsky.social · 8d

Tony has produced seminal work on how cancer cells die, including new assays revealing which cells are poised to die after specific therapeutic treatments.

I wish him luck.

Reposted by Andrei Goga

Ray DuBois MD PhD @duboisrn.bsky.social · 8d

We have a new #NCI Director who was just sworn in: www.nih.gov/news-events/...

Secretary Kennedy Swears in Dr. Anthony Letai as Director of the National Cancer Institute

Dr. Letai will serve as NCI’s 18th director.

www.nih.gov

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Reposted by Andrei Goga

Jason Moore @moorejh.bsky.social · 10d

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Andrea Love, PhD | Biomedical Scientist @drandrealove.bsky.social · 11d

Influencers are selling homeopathy as Tylenol “alternatives” — it’s NOT.

⚠️Homeopathy is a scam created in 1796 by a German guy with NO plausibility or evidence.

Premise:
1️⃣ what causes a symptom will cure an illness w/the symptom
2️⃣ it’s more potent the more it’s diluted

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Reposted by Andrei Goga

Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · Aug 5

Karin Shamardani, DDS/PhD candidate, is working with Jeff Bush @jeffbush.bsky.social to study how Efnb1 and the understudied actin-regulator gene Shrm4 interact to control palatal outgrowth and mesenchymal organization during craniofacial development.

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Reposted by Andrei Goga

Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · 19d

Kyle Jacobs, a Biomedical Sciences PhD candidate in the Kutys Lab, is studying mechanisms of blood vessel inflammation and how this inflammation is dysregulated in diseases like atherosclerosis.

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Reposted by Andrei Goga

Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · 19d

Ting, a postdoc in the L’Etoile lab @girlsinscience.bsky.social, was recently awarded the BARI Postdoctoral Fellowship to study how nights of poor sleep contribute to age-related memory decline in tiny roundworms, which—like humans—also experience sleep loss and memory deterioration as they age.

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Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · 18d

Wrapping up National Postdoc Appreciation Week with a big thank you to our outstanding postdocs! #ucsfNPAW #UCSFpostdocs

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Reposted by Andrei Goga

Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · 19d

Happy National Postdoc Appreciation Week! We are celebrating all the incredible postdocs in the CTB Department! Thank you for your dedication and the vital role you play in advancing research! We will be introducing some of the postdocs who have joined in 2025. #ucsfNPAW #UCSFpostdocs

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Susan Slusser @susanslusser.bsky.social · 25d

From @shaynarubin and also well done Poseys and Giants!! Buster Posey, Giants raise $1.3M for pediatric cancer research at Oracle Park gala www.sfchronicle.com/sports/giant... via @sfchronicle

Buster Posey, Giants raise $1.3M for pediatric cancer research at Oracle Park gala

Working with UCSF Benioff Children’s Hospitals and the V Foundation, Buster Posey and the San Francisco Giants raised money at an event that choked up even the famously reserved former catcher.

www.sfchronicle.com

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Andrei Goga @andreigoga.bsky.social · 25d

I was there. The game was amazing with a walk-off grand slam in the bottom of the 10th inning. Watching someone eat so many nuggets was otherwise horrifying.

Reposted by Andrei Goga

Bruce Lee @b-lee253.bsky.social · 28d

giants win while mets, padres, and cardinals all lose

great day!

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Ray DuBois MD PhD @duboisrn.bsky.social · 29d

A mega-merger for #cancer #research:

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Sarah Boyle @drsarahboyle.bsky.social · 29d

Was my pleasure to moderate the panel today at the inaugural Female Fellows symposium “Balancing Acts”. An insightful, open and frank discussion on juggling a scientific career with caring, part time work and leave, and a real sense of solidarity.

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Andrei Goga @andreigoga.bsky.social · 29d

Enjoyed the Physics of Life Symposium today @UCSF

Reposted by Andrei Goga

Max Heiman @heiman.bsky.social · Sep 7

New preprint!

How are developmental cycles coordinated across cell types?

It turns out that, like Geppetto's cuckoo clocks in the GIF below, individual cell types are each performing their own little crazy routine, but all in sync with each other.

a bunch of clocks are hanging on a wall including one that says ' 3:00 ' on it

ALT: a bunch of clocks are hanging on a wall including one that says ' 3:00 ' on it

media.tenor.com

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Andrei Goga @andreigoga.bsky.social · Sep 5

Interesting and terrifying article. Cancer cells also do something analogous to this type of dormancy to avoid most treatments. Leading to serious challenges for eliminating metastases. 🧪

Reposted by Andrei Goga

Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · Aug 26

We are thrilled that Hydronovo www.hydronovo.com has been awarded an NIH SBIR grant to develop Ceviginate, a new therapeutic for regenerating salivary gland function in debilitating xerostomia. The discoveries for this breakthrough come from the lab of Sarah Knox in CTB!

www.hydronovo.com

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Kristy A. Brown, PhD @drkristyabrown.bsky.social · Aug 24

Beautiful day for the Head for the Cure 5k to raise funds, awareness and hope for the Kansas brain cancer community. What a turnout! Looks like there may have been nearly 2,800 participants towards a goal of raising $700,000.
@kucancercenter.bsky.social

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Gabe Ortíz @tusk81.bsky.social · Aug 23

It’s my opinion that humanitarian and musical genius Dolly Parton (as well as Chef José Andrés) deserves the Nobel Peace Prize. tucson.com/life-enterta...

2,000-plus Pima County kids get free books through Dolly Parton's program

Even her biggest fans have trouble choosing Dolly Parton’s greatest hit.

tucson.com

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Andrei Goga @andreigoga.bsky.social · Aug 20

New work from stellar scientists Jeremy Williams and Roman Camarda. Many contributors including the amazing Zena Werb and Atul Butte

Work explores how breast cancer cells interact directly with adipocytes via gap junctions, leading to lipid release.
@ctbatucsf.bsky.social @ucsfcancer.bsky.social

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

Nature Communications - Breast cancer cells interact with neighbouring adipocytes, but the mechanisms are not fully understood. Here, the authors show that triple-negative breast cancer (TNBC)...

www.nature.com

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Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · Aug 5

The Department of Cell and Tissue Biology has outstanding graduate students from several different programs at UCSF. We are grateful! Over the next several weeks, we will highlight some of these students and share their research focus.

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Reposted by Andrei Goga

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · Aug 1

Alanine Catabolism as a Targetable Vulnerability for MYC-Driven Liver Cancer https://www.biorxiv.org/content/10.1101/2025.07.29.667471v1

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Andrei Goga @andreigoga.bsky.social · Aug 1

We find that genetic or chemical inhibition of GPT2, a key transaminase in MYC-high cancers, prevents tumor formation and attenuates the growth of established cancers. #HCC 🧪

Thanks to many who contributed including: Drs. Joyce Lee, Katie Kelley, and Heather Christofk and lab.

Explainer to follow.

Andrei Goga @andreigoga.bsky.social · Aug 1

Our latest on cancer metabolism by star student Tonatiuh Montoya @ctbatucsf.bsky.social @ucsfcancer.bsky.social

Liver cancers driven by the MYC oncogene are reliant on alanine metabolism. Alanine is the second most abundant amino acid and can partially substitute for glucose and glutamine. 🧪

Alanine Catabolism as a Targetable Vulnerability for MYC-Driven Liver Cancer

Liver cancer is a leading cause of cancer-related death world-wide in part due to the shortage of effective therapies, and MYC overexpression defines an aggressive and especially difficult to treat su...

www.biorxiv.org

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