Jei Diwakar
@jei-diwakar.bsky.social
140 followers
360 following
2 posts
Full Name: Jeisimhan Diwakar. PhD student @Bonev_Lab. Previously at Oxford. Interested in TFs and the 3D genome in the cortex.
@NucleateHQ community member.
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Reposted by Jei Diwakar
Jei Diwakar
@jei-diwakar.bsky.social
· Jun 27
Reposted by Jei Diwakar
Boyan Bonev
@boyanbonev.bsky.social
· Apr 4
Neural stem cell epigenomes and fate bias are temporally coordinated during corticogenesis
The cerebral cortex orchestrates complex cognitive functions, yet how its distinct temporal lineages are molecularly patterned during development remains unresolved. Here, we integrate single-cell tra...
www.biorxiv.org
Reposted by Jei Diwakar
Reposted by Jei Diwakar
Boyan Bonev
@boyanbonev.bsky.social
· Mar 13
3D Epigenome Evolution Underlies Divergent Gene Regulatory Programs in Primate Neural Development
The expansion of the neocortex is a hallmark of human evolution and is closely linked to neural stem cell biology. Yet, the epigenetic mechanisms driving divergent gene regulation during primate neuro...
www.biorxiv.org
Reposted by Jei Diwakar
Meghana Oak
@meghana-oak.bsky.social
· Jan 22
H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development
In the life of a vertebrate embryo, gene expression is initiated for the first time at zygotic genome activation (ZGA). Maternally expressed transcription factors present in the embryo are essential f...
doi.org