Jenny Dickens
@jennydickens41.bsky.social
230 followers
89 following
22 posts
Academic physician with an interest in familial ILD and and complex lung disease models. Also a cellist, runner, baker and frazzled mum of two
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Reposted by Jenny Dickens
Reposted by Jenny Dickens
Reposted by Jenny Dickens
Jenny Dickens
@jennydickens41.bsky.social
· Jul 22
Endogenous gene editing of alveolar organoids reveals that expression of pathogenic variant SFTPC-I73T disrupts endosomal function, epithelial polarity and wound healing
Background: Idiopathic pulmonary fibrosis is a fatal lung disease of progressive lung parenchymal scarring caused by the aberrant response of an alveolar epithelium repeatedly exposed to injury. Under...
www.biorxiv.org
Jenny Dickens
@jennydickens41.bsky.social
· Jun 19
Jenny Dickens
@jennydickens41.bsky.social
· May 23
Jenny Dickens
@jennydickens41.bsky.social
· Apr 12
Jenny Dickens
@jennydickens41.bsky.social
· Feb 14
Reposted by Jenny Dickens
Reposted by Jenny Dickens
Reposted by Jenny Dickens
Jenny Dickens
@jennydickens41.bsky.social
· Jan 17
Jenny Dickens
@jennydickens41.bsky.social
· Jan 16
Jenny Dickens
@jennydickens41.bsky.social
· Jan 15
Jenny Dickens
@jennydickens41.bsky.social
· Jan 15
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease | The EMBO Journal
imageimageDisorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature human fetal-derived alveolar type 2 ...
www.embopress.org