Jie Luo
@jie-luo-lab.bsky.social
Assistant Professor @PurdueIPPH | High-Precision Biomedical Imaging | Nucleic Acids/Protein Delivery | Physiology and Pathology | Views are my own.
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Jie Luo
@jie-luo-lab.bsky.social
· Jan 14
Twitter:
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
Excited to share our new technique for visualizing nanoparticles or viruses at single-cell resolution across the entire mouse body! This approach uses deep learning for precise quantification, and we’ve made the code available-give it a try with your dataset! Thanks so much to the whole team!
I am honored to give a talk at #SfN and to introduce my new lab, which is developing new technologies to visualize macromolecules at the whole-body scale and to identify new targets for cancer and Alzheimer’s disease.
#SfN #Purdue #TissueClearing #DrugDiscovery #Cancer #Alzheimer
#SfN #Purdue #TissueClearing #DrugDiscovery #Cancer #Alzheimer
November 20, 2025 at 7:02 PM
I am honored to give a talk at #SfN and to introduce my new lab, which is developing new technologies to visualize macromolecules at the whole-body scale and to identify new targets for cancer and Alzheimer’s disease.
#SfN #Purdue #TissueClearing #DrugDiscovery #Cancer #Alzheimer
#SfN #Purdue #TissueClearing #DrugDiscovery #Cancer #Alzheimer
Reposted by Jie Luo
Imagine being able to visualize life-saving drugs or genetic therapies being delivered to the target cells without causing harmful side effects? Another amazing study from
@erturklab.bsky.social at @naturebiotech.bsky.social 🤩
@erturklab.bsky.social at @naturebiotech.bsky.social 🤩
January 15, 2025 at 4:46 PM
Imagine being able to visualize life-saving drugs or genetic therapies being delivered to the target cells without causing harmful side effects? Another amazing study from
@erturklab.bsky.social at @naturebiotech.bsky.social 🤩
@erturklab.bsky.social at @naturebiotech.bsky.social 🤩
Reposted by Jie Luo
This is amazing!!! @caldaslab.bsky.social is excited about this approach to study cancer xenograft models!
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
www.nature.com
January 14, 2025 at 11:28 PM
This is amazing!!! @caldaslab.bsky.social is excited about this approach to study cancer xenograft models!
Reposted by Jie Luo
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - @erturklab.bsky.social @hendrikdietz.bsky.social go.nature.com/4gNLjeC
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
go.nature.com
January 14, 2025 at 5:21 PM
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - @erturklab.bsky.social @hendrikdietz.bsky.social go.nature.com/4gNLjeC
Reposted by Jie Luo
Twitter:
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
January 14, 2025 at 3:25 PM
Excited to share our new technique for visualizing nanoparticles or viruses at single-cell resolution across the entire mouse body! This approach uses deep learning for precise quantification, and we’ve made the code available-give it a try with your dataset! Thanks so much to the whole team!
Twitter:
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
January 14, 2025 at 3:30 PM
Excited to share our new technique for visualizing nanoparticles or viruses at single-cell resolution across the entire mouse body! This approach uses deep learning for precise quantification, and we’ve made the code available-give it a try with your dataset! Thanks so much to the whole team!
Reposted by Jie Luo
Look what came in the mail!!
January 11, 2025 at 12:24 AM
Look what came in the mail!!
Reposted by Jie Luo
Keep forgetting to include hashtags, like #immunosky!
The last Cell issue of the year is online. This one is a doozy if you like interferons (as I do!) or transposons and ERVs (and who doesn't?!) There's also cool stem cell and dev bio in this issue, immune responses to Zika during pregnancy... cancer, plants... cool stuff! www.cell.com/cell/issue?p...
December 27, 2024 at 1:45 PM
Keep forgetting to include hashtags, like #immunosky!
Reposted by Jie Luo
My holiday gift to all of you: The editors of @science.org's favorite papers of 2024, all wrapped up nicely in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
December 26, 2024 at 10:50 PM
My holiday gift to all of you: The editors of @science.org's favorite papers of 2024, all wrapped up nicely in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
Reposted by Jie Luo
Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/...
January 4, 2025 at 12:34 AM
Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/...
Thrilled to share I’ll officially start next Monday as a tenure-track Assistant Professor at the Department of Industrial and Molecular Pharmaceutics, Purdue University! My lab will focus on high-precision in vivo biomedical imaging for drug discovery.
January 5, 2025 at 8:14 PM
Thrilled to share I’ll officially start next Monday as a tenure-track Assistant Professor at the Department of Industrial and Molecular Pharmaceutics, Purdue University! My lab will focus on high-precision in vivo biomedical imaging for drug discovery.