Markus Elsner
@markuselsner.bsky.social
Deputy Director of the Institute for Intelligent Biotechnologies at HelmholtzMunich, former editor @naturebiotech.bsky.social, all views expressed here are my own
Reposted by Markus Elsner
Job alert! Assistant professor position in the Department of Molecular Genetics (University of Toronto). Amazing department and city. jobs.utoronto.ca/job/Toronto-... Please share.
Assistant Professor - Virology
Assistant Professor - Virology
jobs.utoronto.ca
January 15, 2026 at 8:04 PM
Job alert! Assistant professor position in the Department of Molecular Genetics (University of Toronto). Amazing department and city. jobs.utoronto.ca/job/Toronto-... Please share.
Reposted by Markus Elsner
🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org
A genetically encoded device for transcriptome storage in mammalian cells
Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...
www.science.org
January 15, 2026 at 8:31 PM
🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org
uuuh, this sounds super interesting. If it works as advertised, I could imagine soooo many applications:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A genetically encoded device for transcriptome storage in mammalian cells
Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...
www.science.org
January 15, 2026 at 8:51 PM
uuuh, this sounds super interesting. If it works as advertised, I could imagine soooo many applications:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Markus Elsner
Big news! The Data Management team/Data Science Centre at EMBL (i.e. my team) is hiring for a position based in Heidelberg (but working across all sites!). We are looking for a scientific workflows developer that will focus on multimodal pipelines. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Scientific Workflows Developer
The European Molecular Biology Laboratory (EMBL) is Europe’s life sciences laboratory – an intergovernmental organisation with more than 110 independent research groups and service teams covering the ...
embl.wd103.myworkdayjobs.com
January 14, 2026 at 9:37 AM
Big news! The Data Management team/Data Science Centre at EMBL (i.e. my team) is hiring for a position based in Heidelberg (but working across all sites!). We are looking for a scientific workflows developer that will focus on multimodal pipelines. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Markus Elsner
Our review on AI agents in cancer research and oncology is out in @natrevcancer.nature.com. Already partly outdated at publication, but hopefully still useful. With Daniel Truhn, Shekoofeh Azizi, James Zou, Leonor Cerda-Alberich, Faisal Mahmood -> www.nature.com/articles/s41...
Client Challenge
www.nature.com
January 13, 2026 at 9:44 PM
Our review on AI agents in cancer research and oncology is out in @natrevcancer.nature.com. Already partly outdated at publication, but hopefully still useful. With Daniel Truhn, Shekoofeh Azizi, James Zou, Leonor Cerda-Alberich, Faisal Mahmood -> www.nature.com/articles/s41...
Reposted by Markus Elsner
Want to learn state-of-the-art deep learning techniques for microscopy image analysis? Apply by Jan. 15 to join us for a bootcamp at HHMI’s Janelia Research Campus. Gain hands-on experience with tools & frameworks you can use in your own research: bit.ly/4sqejiG 🧪
Deep Learning for Microscopy Image Analysis
Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,
bit.ly
January 13, 2026 at 9:33 PM
Want to learn state-of-the-art deep learning techniques for microscopy image analysis? Apply by Jan. 15 to join us for a bootcamp at HHMI’s Janelia Research Campus. Gain hands-on experience with tools & frameworks you can use in your own research: bit.ly/4sqejiG 🧪
Interesting!
3 papers in Cell @cellpress.bsky.social today exploring the mechanistic connection between Epstein-Barr virus and multiple sclerosis #MultipleSclerosis
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 14, 2026 at 4:39 AM
Interesting!
Come work with us!
We’re hiring – Computer Science PhD at iBIO (Helmholtz Munich / LMU).
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Helmholtz Munich hiring PhD Position – Deep Learning for Multi-Omics Atlases of the Mammalian Body in Greater Munich Metropolitan Area | LinkedIn
Posted 8:43:27 PM. AI Scientist - PhD Position Institute for Intelligent Biotechnologies (iBIO), Helmholtz Munich /…See this and similar jobs on LinkedIn.
www.linkedin.com
January 14, 2026 at 4:36 AM
Come work with us!
Reposted by Markus Elsner
We’re hiring – Computer Science PhD at iBIO (Helmholtz Munich / LMU).
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Helmholtz Munich hiring PhD Position – Deep Learning for Multi-Omics Atlases of the Mammalian Body in Greater Munich Metropolitan Area | LinkedIn
Posted 8:43:27 PM. AI Scientist - PhD Position Institute for Intelligent Biotechnologies (iBIO), Helmholtz Munich /…See this and similar jobs on LinkedIn.
www.linkedin.com
January 13, 2026 at 8:51 PM
We’re hiring – Computer Science PhD at iBIO (Helmholtz Munich / LMU).
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Reposted by Markus Elsner
Im Sommersemester 2026 können wir Doktorand:innen, die Geförderte oder Alumni der Carl-Zeiss-Stiftung sind, kostenlose Teilnahmeplätze in der
➡️ CZS STEM Impact School ⬅️ anbieten.
Das dreitägige Seminar wird von @w-i-d.de angeboten und durch die #CZS gefördert.
Anmeldung: tinyurl.com/CZS-STEM-Imp...
➡️ CZS STEM Impact School ⬅️ anbieten.
Das dreitägige Seminar wird von @w-i-d.de angeboten und durch die #CZS gefördert.
Anmeldung: tinyurl.com/CZS-STEM-Imp...
January 12, 2026 at 9:04 AM
Im Sommersemester 2026 können wir Doktorand:innen, die Geförderte oder Alumni der Carl-Zeiss-Stiftung sind, kostenlose Teilnahmeplätze in der
➡️ CZS STEM Impact School ⬅️ anbieten.
Das dreitägige Seminar wird von @w-i-d.de angeboten und durch die #CZS gefördert.
Anmeldung: tinyurl.com/CZS-STEM-Imp...
➡️ CZS STEM Impact School ⬅️ anbieten.
Das dreitägige Seminar wird von @w-i-d.de angeboten und durch die #CZS gefördert.
Anmeldung: tinyurl.com/CZS-STEM-Imp...
Reposted by Markus Elsner
Targeted delivery of genome editors in vivo - @doudna-lab.bsky.social @innovativegenomics.bsky.social go.nature.com/4qKp6Tb
January 12, 2026 at 5:35 PM
Targeted delivery of genome editors in vivo - @doudna-lab.bsky.social @innovativegenomics.bsky.social go.nature.com/4qKp6Tb
Reposted by Markus Elsner
Don't miss the early-bird deadline for our Imaging Cell Dynamics meeting taking place in Catalonia, Spain in May.
Early-bird deadline: Friday 16 January
View the preliminary programme here: www.biologists.com/wp-content/u...
#JCSImaging
Early-bird deadline: Friday 16 January
View the preliminary programme here: www.biologists.com/wp-content/u...
#JCSImaging
January 12, 2026 at 10:38 AM
Don't miss the early-bird deadline for our Imaging Cell Dynamics meeting taking place in Catalonia, Spain in May.
Early-bird deadline: Friday 16 January
View the preliminary programme here: www.biologists.com/wp-content/u...
#JCSImaging
Early-bird deadline: Friday 16 January
View the preliminary programme here: www.biologists.com/wp-content/u...
#JCSImaging
Reposted by Markus Elsner
Reposted by Markus Elsner
Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info.
Deadline 8 Feb. Apply here:
umustipendie.varbi.com/en/what:job/...
#virus #virology #teamtomo #cryoEM
Deadline 8 Feb. Apply here:
umustipendie.varbi.com/en/what:job/...
#virus #virology #teamtomo #cryoEM
January 9, 2026 at 1:58 PM
Reposted by Markus Elsner
The contrastive learning framework DrugCLIP enables screening of ~10,000 human proteins against 500 million compounds in under 24 hours, achieving experimentally validated hit rate up to 17.5%. #NBThighlight www.science.org/doi/10.1126/...
Deep contrastive learning enables genome-wide virtual screening
Recent breakthroughs in protein structure prediction have opened new avenues for genome-wide drug discovery, yet existing virtual screening methods remain computationally prohibitive. We present DrugC...
www.science.org
January 9, 2026 at 4:44 PM
The contrastive learning framework DrugCLIP enables screening of ~10,000 human proteins against 500 million compounds in under 24 hours, achieving experimentally validated hit rate up to 17.5%. #NBThighlight www.science.org/doi/10.1126/...
Reposted by Markus Elsner
Human lung explants as a predictive platform for evaluating the on-target, off-tumor toxicity of T cell bispecifics https://www.biorxiv.org/content/10.64898/2026.01.08.698374v1
January 9, 2026 at 9:47 PM
Human lung explants as a predictive platform for evaluating the on-target, off-tumor toxicity of T cell bispecifics https://www.biorxiv.org/content/10.64898/2026.01.08.698374v1
Reposted by Markus Elsner
I am looking for two postdocs to join our lab
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
January 9, 2026 at 3:17 PM
I am looking for two postdocs to join our lab
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
Thank you so much for publishing (@natbiotech.nature.com)
and highlighting ( @springernature.com)our work!
and highlighting ( @springernature.com)our work!
One of our top-rated posts on @altmetric.com in 2025 was published in @natbiotech.nature.com. You can read 'Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning' open access here: spklr.io/63322BQufI
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
spklr.io
January 8, 2026 at 12:47 PM
Thank you so much for publishing (@natbiotech.nature.com)
and highlighting ( @springernature.com)our work!
and highlighting ( @springernature.com)our work!
Reposted by Markus Elsner
"Cancer pathway connectivity resolved by drug
perturbation and RNA sequencing" presents a unique RNA-seq after perturbation dataset of B cell cancer samples from 116 patients, (almost) each perturbed with 10 small molecule compounds & control.
www.biorxiv.org/content/10.6...
perturbation and RNA sequencing" presents a unique RNA-seq after perturbation dataset of B cell cancer samples from 116 patients, (almost) each perturbed with 10 small molecule compounds & control.
www.biorxiv.org/content/10.6...
January 7, 2026 at 9:28 AM
"Cancer pathway connectivity resolved by drug
perturbation and RNA sequencing" presents a unique RNA-seq after perturbation dataset of B cell cancer samples from 116 patients, (almost) each perturbed with 10 small molecule compounds & control.
www.biorxiv.org/content/10.6...
perturbation and RNA sequencing" presents a unique RNA-seq after perturbation dataset of B cell cancer samples from 116 patients, (almost) each perturbed with 10 small molecule compounds & control.
www.biorxiv.org/content/10.6...
Hope Denmark is beefing up security for its Prime Minister.
Never thought that I would think that war with the US is more likely than a war with Russia in 2026.
That I think that any war is even a remote possibility is really frightening.
Never thought that I would think that war with the US is more likely than a war with Russia in 2026.
That I think that any war is even a remote possibility is really frightening.
January 5, 2026 at 2:24 PM
Hope Denmark is beefing up security for its Prime Minister.
Never thought that I would think that war with the US is more likely than a war with Russia in 2026.
That I think that any war is even a remote possibility is really frightening.
Never thought that I would think that war with the US is more likely than a war with Russia in 2026.
That I think that any war is even a remote possibility is really frightening.
Reposted by Markus Elsner
Eleven clinical trials that will shape medicine in 2026
Happy to see a lot of cell-based therapies!
Happy to see a lot of cell-based therapies!
January 4, 2026 at 4:15 PM
Eleven clinical trials that will shape medicine in 2026
Happy to see a lot of cell-based therapies!
Happy to see a lot of cell-based therapies!
Ok, he was unhinged as usual, but seriously Trump did not seem well.
January 3, 2026 at 11:36 PM
Ok, he was unhinged as usual, but seriously Trump did not seem well.
Interesting!
Generation of T cells with reduced off-target cross-reactivities by engineering co-signaling receptors
CD5, CD8, or CD4(w/o changing TCR)
www.nature.com/articles/s41... @natbiomedeng.nature.com @tcell.bsky.social @ox.ac.uk
CD5, CD8, or CD4(w/o changing TCR)
www.nature.com/articles/s41... @natbiomedeng.nature.com @tcell.bsky.social @ox.ac.uk
January 3, 2026 at 12:22 PM
Interesting!
Reposted by Markus Elsner
Here is the link to download the PDF of my course#5 on Biological computation. I present & discuss Self-tuning, Adaptation and Learning in biological (non-neuronal) systems, in particular during embryonic development.
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
January 3, 2026 at 9:47 AM
Here is the link to download the PDF of my course#5 on Biological computation. I present & discuss Self-tuning, Adaptation and Learning in biological (non-neuronal) systems, in particular during embryonic development.
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
Reposted by Markus Elsner
The cryo cyclical multiplexing expansion microscopy (Cy-ExM) preprint from
@seweryn-galecki.bsky.social , @kevin-dean.bsky.social et al is online.
20 targets across an entire cell. Mr. Snouty also joined the fun.
www.biorxiv.org/content/10.6...
@seweryn-galecki.bsky.social , @kevin-dean.bsky.social et al is online.
20 targets across an entire cell. Mr. Snouty also joined the fun.
www.biorxiv.org/content/10.6...
January 2, 2026 at 7:39 PM
The cryo cyclical multiplexing expansion microscopy (Cy-ExM) preprint from
@seweryn-galecki.bsky.social , @kevin-dean.bsky.social et al is online.
20 targets across an entire cell. Mr. Snouty also joined the fun.
www.biorxiv.org/content/10.6...
@seweryn-galecki.bsky.social , @kevin-dean.bsky.social et al is online.
20 targets across an entire cell. Mr. Snouty also joined the fun.
www.biorxiv.org/content/10.6...