Oh, I see! That's the 1% per year rule that some people write about? Thanks for the response and good luck carrying this forward!

Hi Roman, very cool paper! Nice work. I wonder how you envision that could be applied in the clinic? Wouldn't you expect any remaining, mutated cells to relatively quick overgrow again?

Cool pre-print, addressing a question that I've been wondering about for a while! Congrats :)

Thanks :)

Danke, Björn!

Thanks, Kilian!

Hi Loic, why did you exclude very rare variants with frequency <0.01%? Don't we have many of these and what would you guess is their contribution? The most severe and impactful variants are usually very rare.

I think you putting the "obivous" into a formal, non-rethoric frame out there for people to point to is amazing. As long as these assertions stand there and it's only obvious to the experts why they're false, they can convince a lot of people. You're giving people tools to refute this nonsense.

Thank you, Zach! Someone has to clean this mess up and I can only imagine how tideous it is.

It was a great pleasure to join the symposium, meet with great scientists and learn new things! Congrats again for the award!

Whaaaat!=!=!=