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Reposted by Jonathan Kipnis

NPR @npr.org · 15d

The 2025 Booker shortlist is made up of works by veteran authors, many of whom have several books under their belts — and a couple that have been on this list before.

The Booker shortlist honors authors 'in total command' of their craft

The 2025 Booker shortlist is made up of works by veteran authors, many of whom have several books under their belts — and a couple that have been on this list before.

n.pr

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Reposted by Jonathan Kipnis

Aleksandra Deczkowska @adeczkowska.bsky.social · 20d

Some thoughts on meningeal mast cells inspired by Xinzhong Dong and @jonykipnis.bsky.social recent (and AWESOME) papers. Lead: @fakesamir.bsky.social

www.cell.com/trends/immun...

www.cell.com

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Reposted by Jonathan Kipnis

Glymphatic Research Network @glymphaticrnet.bsky.social · 26d

📅 Save the Date: Oxford 2026 Glymphatic Research Symposium!

• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow

Looking forward to seeing you there! 🧠

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Reposted by Jonathan Kipnis

RTN Conference @rtnconference.bsky.social · Aug 25

#ReThinkNeuroimmunology!
3 days
27 speakers
7 selected talks
2 panel discussions
>400 registered
Submit your abstract by August 28th for #RTN2025.
🔗 genelayinstitute.org/rtn/ 🧪
@quintanalabhms.bsky.social @bethstevenslab.bsky.social @jonykipnis.bsky.social @idoamitlab.bsky.social #RejaneRua

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Reposted by Jonathan Kipnis

Martin Kampmann @kampmann.bsky.social · Aug 22

Excited that the paper presenting our mouse brain in vivo CRISPR screening platform is out today in @natneuro.nature.com!

Great team effort, led by Biswa Ramani and @ivlrose.bsky.social in the Kampmann lab.

www.nature.com/articles/s41...

CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes - Nature Neuroscience

The authors developed an adeno-associated virus-based high-throughput in vivo CRISPR screening platform for endogenous mouse brain cell types. Using this platform, they define genes and pathways essen...

www.nature.com

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Jonathan Kipnis @jonykipnis.bsky.social · Aug 16

We are all in this shit… 🤦‍♂️

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Jonathan Kipnis @jonykipnis.bsky.social · Aug 2

🙏🙏🙏

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Jonathan Kipnis @jonykipnis.bsky.social · Aug 1

Thank you for inviting me back!

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Reposted by Jonathan Kipnis

The American Association of Immunologists @aai.org · Jul 31

In his “Neuroimmunology” lecture, @jonykipnis.bsky.social (@washumedicine.bsky.social) questioned what makes the CNS “immune privileged” if its antigens reach T cells via lymphatics and meningeal APCs—reshaping how we think about brain-immune interactions. #AAIcourses

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Jonathan Kipnis @jonykipnis.bsky.social · Jul 24

Excited to share our new work, led by an exceptional graduate student, Tornike Mamuladze, on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || www.cell.com/cell/fulltex...

Mast cells regulate the brain-dura interface and CSF dynamics

Dural mast cells control cerebrospinal fluid dynamics at critical brain-dura interfaces, specifically arachnoid cuff exit points. Their activation limits pathogen brain entry via histamine-induced vas...

www.cell.com

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Jonathan Kipnis @jonykipnis.bsky.social · Jun 28

Brilliant ⁦‪BIG center seminar by ex-postdoc fellow, now associate professor ⁦‪@MayoClinic‬⁩, @da-mesquita.bsky.social, who was our student-invited speaker. 👏👏👏

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Jonathan Kipnis @jonykipnis.bsky.social · Jun 19

Here is another reason to come back to Twitter 😂

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Reposted by Jonathan Kipnis

Nature Neuroscience @natneuro.nature.com · Jun 16

A route for cerebrospinal fluid flow through leptomeningeal arterial–venous overlaps enables macromolecule and fluid shunting

@jonykipnis.bsky.social

www.nature.com/articles/s41...

A route for cerebrospinal fluid flow through leptomeningeal arterial–venous overlaps enables macromolecule and fluid shunting - Nature Neuroscience

The authors describe a mechanism for the clearance of macromolecules from cerebrospinal fluid in which macromolecules traverse from periarterial to perivenous spaces, at sites where intersecting lepto...

www.nature.com

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Reposted by Jonathan Kipnis

Sabela DeScience @sabeladescience.bsky.social · Jun 10

🔗 By @leonsmyth.bsky.social & @jonykipnis.bsky.social at Nature Reviews Immunology: www.nature.com/articles/s41...
(10/11)

Redefining CNS immune privilege - Nature Reviews Immunology

In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to involve isolation of the central ner...

www.nature.com

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Jonathan Kipnis @jonykipnis.bsky.social · Jun 14

Haha! I need to come here more often to check on my posts 😂… not every day I get a Nobel Laureate comment 🤩! So, as far as I’m concerned, this one is now my #1 post of all times! And I do miss you on Twitter!

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Jonathan Kipnis @jonykipnis.bsky.social · Jun 6

Dear all, come back to Twitter. It’s more exciting there!

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Reposted by Jonathan Kipnis

Immunity @cp-immunity.bsky.social · May 20

Check out our special issue! The beautiful cover was designed by @ella-maru.bsky.social, working with @jonykipnis.bsky.social & Mitchell (Min Woo) Kim. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...

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Jonathan Kipnis @jonykipnis.bsky.social · May 18

What’s better than The Great Nerve by the amazing Kevin Tracey? Two copies of The Great Nerve 🤩 One for home and one for the lab! Amazing read and truly incredible science!

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Reposted by Jonathan Kipnis

Cell - a Cell Press journal @cp-cell.bsky.social · May 16

and how dysfunctional meningeal lymphatics regulate synaptic physiology in a microglia-dependent manner
www.cell.com/cell/fulltex... @jonykipnis.bsky.social

Meningeal lymphatics-microglia axis regulates synaptic physiology

Dysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner. Enhancing the funct...

www.cell.com

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Reposted by Jonathan Kipnis

Cell - a Cell Press journal @cp-cell.bsky.social · May 16

The new issue is out! 👉 cell.com/cell/current

On the cover, Beckwith and Brunner et al. uncover that chromosomes self-organize into their characteristic mitotic rod shape through the formation of large and extensively overlapping DNA loops

📷credit: Andreas Brunner.

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Reposted by Jonathan Kipnis

Immunity @cp-immunity.bsky.social · May 13

May issue is online! Explore reviews on the #neuroimmune axis! The beautiful cover was designed by Ella Marushchenko, working with @jonykipnis.bsky.social. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...