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Reposted by Jordan Hamm

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Aug 19

Visuomotor mismatch EEG responses in occipital cortex of freely moving human subjects https://www.biorxiv.org/content/10.1101/2025.08.14.670295v1

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Reposted by Jordan Hamm

Sofiya Hupalo @sofiyahupalo.bsky.social · Aug 12

Just learned that my @acnporg.bsky.social panel was accepted!

With my colleagues Zoë Hughes, @jordanhamm.bsky.social, Bryan Baxter & Patricio O'Donnell, our #ACNP2026 panel will highlight cross-species approaches using functional brain-based biomarkers to address translational gaps in psychiatry

a group of people jumping off a cliff into a body of water with a caption that says colnah.cy

Alt: people jumping off a cliff into a body of water

media.tenor.com

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Jordan Hamm @jordanhamm.bsky.social · Aug 5

First lab outing since the move to NYC.... feeling so lucky to have such a talented and fun group! with Lital Rachmany, @adhockley.bsky.social, me, Molly Hornick, Fumiyasu Imai, and @cgalli-io.bsky.social

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Jordan Hamm @jordanhamm.bsky.social · May 21

Paper forthcoming. Thankfully, I’ve managed to keep him in my lab as a Research Scientist at the Nathan Kline Institute and NYU.

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Jordan Hamm @jordanhamm.bsky.social · May 21

and designed beautiful intuitive figures. For his final project, Connor wasn't afraid to dig into a well-worn topic in neuropsychiatry — how and why NMDA-receptor antagonists exert such powerful yet nuanced effects on brain dynamics, perception, and cognition— and he was able to glean new insights!

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Jordan Hamm @jordanhamm.bsky.social · May 21

In his time as a graduate student, Connor excelled at every aspect of research. He set up complex equipment, conducted extremely high quality recordings, analysed data in thoughtful and creative ways, applied rigorous statistics, wrote engaging introductions and balanced discussions, ...

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Jordan Hamm @jordanhamm.bsky.social · May 21

I’m delighted to congratulate Dr. Connor Gallimore for successfully defending his dissertation, “Patterns of laminar engagement during visual mismatch processing”. I consider myself lucky that Connor joined my lab in 2019. His CV, though impressive on its own, doesn’t even scratch the surface.

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Jordan Hamm @jordanhamm.bsky.social · Apr 13

Beautiful views and stimulating science discussion this week at University of Zurich/ETH Zurich with Wolfger von der Berhens, Fatih Yanık and many others. Honored to share my work with such a world class group!

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Reposted by Jordan Hamm

Maximiliano José Nigro @maxnigro.bsky.social · Feb 28

There are many studies on cell types and then there is the gold standard.
Beautiful work on the diversity of VIP interneurons by the Rudy lab!

#neuroskyence

www.biorxiv.org/content/10.1...

Inhibitory and disinhibitory VIP IN-mediated circuits in neocortex

Cortical GABAergic interneurons (INs) are comprised of distinct types that provide tailored inhibition to pyramidal cells (PCs) and other INs, thereby enabling precise control of cortical circuit acti...

www.biorxiv.org

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Jordan Hamm @jordanhamm.bsky.social · Feb 27

I'm hiring a full-time research technician to work in my lab at Nathan Kline. Benefits included! Some lab experience preferred... experience with mouse surgeries a huge plus. If you live in NYC, there are two daily shuttles that take ≈20 min from upper manhattan. nki.applicantpro.com/jobs/3663631

Research Technician I (Emotional Brain Institute) (210-2025-06) - Orangeburg, NY

JOB DESCRIPTION: The Emotional Brain Institute (EBI) is a multidisciplinary institute aimed at addressing fundamental questions in neuroscience and neuropsychiatry. We seek to hire a research technici...

nki.applicantpro.com

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Jordan Hamm @jordanhamm.bsky.social · Feb 16

... especially if a sensory cortical region is better understood and more analogous across species. And visual cortex is having a moment lately! pubmed.ncbi.nlm.nih.gov/38548877/

Altered excitatory and inhibitory ionotropic receptor subunit expression in the cortical visuospatial working memory network in schizophrenia - PubMed

Dysfunction of the cortical dorsal visual stream and visuospatial working memory (vsWM) network in individuals with schizophrenia (SZ) likely reflects alterations in both excitatory and inhibitory neu...

pubmed.ncbi.nlm.nih.gov

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Jordan Hamm @jordanhamm.bsky.social · Feb 16

Combined with that recent paper on cell-wise expression of SZ GWAS hits ( doi.org/10.1038/s415... ), this is telling me that translational studies of basic disease mechanisms in schizophrenia need not be limited to -- or even focused on -- prefrontal cortex....

Mapping the cellular etiology of schizophrenia and complex brain phenotypes - Nature Neuroscience

Duncan and colleagues link specific human brain cell types to schizophrenia and other complex brain phenotypes, providing mechanistic insights and a cellular taxonomy for psychiatric disorders.

doi.org

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Jordan Hamm @jordanhamm.bsky.social · Feb 16

New results from study of cortical thickness in 1211 psychosis cases and 734 controls demonstrates that "visual cortex is among the most profoundly affected brain regions", with effect sizes larger than prefrontal regions.

www.medrxiv.org/content/10.1...

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Reposted by Jordan Hamm

Rafael Yuste @rafaelyuste.bsky.social · Feb 10

Press release of our new article in Neuron: How Does the Brain Differentiate New Stimuli From Old Ones? | Columbia News news.columbia.edu/news/how-doe...

How Does the Brain Differentiate New Stimuli From Old Ones?

A study sheds light on how networks in the brain detect new information, offering insight into disorders like schizophrenia.

news.columbia.edu

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Jordan Hamm @jordanhamm.bsky.social · Feb 10

Stimulus features and stimulus context are distinctly represented across populations in both primary and higher order auditory areas.

Through computational modeling, we demonstrate that context and stimulus history may be encoded in ongoing activity in recurrent networks.

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Jordan Hamm @jordanhamm.bsky.social · Feb 10

Our new paper is out in Neuron! We characterize auditory prediction errors across primary and secondary regions, to simple and complex stimuli. Deviance detection (and context) are distinct from basic adaptation -- even in a simple oddball paradigm. 1/2

www.sciencedirect.com/science/arti...

Slow cortical dynamics generate context processing and novelty detection

The cortex amplifies responses to novel stimuli while suppressing redundant ones. Novelty detection is necessary to efficiently process sensory inform…

www.sciencedirect.com

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Reposted by Jordan Hamm

Phil Corlett @philcorlett.bsky.social · Jan 29

Comment on our recent paper challenging the link between MMN dysfunction and positive symptoms:

www.sciencedirect.com/science/arti...

Thanks @mattnour.bsky.social

I may have missed it but cognitive map dysfunction is also unrelated to positive symptoms so far?

If Mismatch Negativity Is the Answer, What Is the Question? On the Nature of Predictive Coding Abnormalities in Psychosis

www.sciencedirect.com

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Jordan Hamm @jordanhamm.bsky.social · Jan 22

www.nature.com/articles/s41...

Lots to unpack in this Nat Neuro paper on schiz genetics (ctx-wide GABA, amygdala, no DA?)

One thing: in terms of exc neurons, a vis-ctx specific cluster (133) and a ctx-wide cluster (123) is as implicated (if not, more) than the most prominent PFC cluster (404).

Mapping the cellular etiology of schizophrenia and complex brain phenotypes - Nature Neuroscience

Duncan and colleagues link specific human brain cell types to schizophrenia and other complex brain phenotypes, providing mechanistic insights and a cellular taxonomy for psychiatric disorders.

www.nature.com

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Reposted by Jordan Hamm

Daniel Trubman @danieltrubman.bsky.social · Jan 19

One of the disappointing trends for urban college neighborhoods over the last few years is the introduction and maintenance of restrictions on access in and thru formerly open walkways.

So it's great to see efforts to protect these public easements.
www.nydailynews.com/2025/01/15/a...

Admission denied: Columbia must reopen its gates

This is an open letter to Columbia University Interim President Katrina Armstrong. Dear President Armstrong,

www.nydailynews.com

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Reposted by Jordan Hamm

Rose Bagot @rcbagot.bsky.social · Jan 9

New lab preprint ! There is a lot of excitement about the therapeutic potential of psilocybin but what is the mechanism? A beautiful body of work from @alexkwan.bsky.social shows that PFC plasticity is important. But how does this unfold and in which cell types?

www.biorxiv.org/content/10.1...

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Reposted by Jordan Hamm

PsyPost @psypost.bsky.social · Jan 7

Individuals with psychosis struggle with visual pattern integration, linked to altered brain activity and weakened connectivity in key visual areas, particularly during tasks involving background noise #Psychosis #MentalHealth #VisualPerception #Neuroscience #BrainConnectivity

Study links visual perception deficits in psychosis to altered brain connectivity

Individuals with psychosis struggle with visual pattern integration, linked to altered brain activity and weakened connectivity in key visual areas, particularly during tasks involving background noise

www.psypost.org

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Jordan Hamm @jordanhamm.bsky.social · Dec 21

Wow! Really important connection! Well done silvia and @haberlmatt.bsky.social and team!

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Jordan Hamm @jordanhamm.bsky.social · Dec 17

We're all parts of institutions, and we're all vexed by seemingly pointless obstacles and bureaucracy at one point. Chesterton's fence provides a great lesson -- "Do not remove a fence until you know why it was constructed in the first place" #neuroskyence

fs.blog/chestertons-...

Chesterton’s Fence: A Lesson in Thinking

A core component of making great decisions is understanding previous decisions. If we don’t understand how we got “here,” we run the risk of making things much worse.

fs.blog

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Reposted by Jordan Hamm

Shari Wiseman @shariwiseman.bsky.social · Dec 9

Nature Neuroscience is hiring a computational/systems/cognitive editor! Come join our team! Happy to answer any questions.

springernature.wd3.myworkdayjobs.com/SpringerNatu...

Associate or Senior Editor, Nature Neuroscience

Job Title: Associate or Senior Editor, Nature Neuroscience Location: New York, Jersey City, Philadelphia, Washington D.C., Berlin or Shanghai Application Deadline: January 6, 2025 About Springer Natur...

springernature.wd3.myworkdayjobs.com

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Reposted by Jordan Hamm

Rebecca Solnit @rebeccasolnit.bsky.social · Dec 5

Here is a somber truth of creative life. If it goes well, people will begin to ask you for things. Each of those things, no matter how kind or flattering or genuine or even beneficial to your own career and finances as well as someone else's, will pull you from your true purpose.

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