Phil Corlett
@philcorlett.bsky.social
I study how the brain makes up the mind
Delusions, Hallucinations
Prediction Errors, Priors
Beliefs, Perception
He/Him
belieflab.yale.edu
Delusions, Hallucinations
Prediction Errors, Priors
Beliefs, Perception
He/Him
belieflab.yale.edu
Reposted by Phil Corlett
"I say we take off and nuke the site from orbit. It's the only way to be sure."
November 27, 2025 at 2:30 AM
"I say we take off and nuke the site from orbit. It's the only way to be sure."
Reposted by Phil Corlett
Altered striatal dopamine dynamics and behavior in Grin2a mutant mice, a genetic mouse model of schizophrenia https://www.biorxiv.org/content/10.1101/2025.11.24.690326v1
November 26, 2025 at 7:15 AM
Altered striatal dopamine dynamics and behavior in Grin2a mutant mice, a genetic mouse model of schizophrenia https://www.biorxiv.org/content/10.1101/2025.11.24.690326v1
Reposted by Phil Corlett
The trial found small reductions in voice severity at 12 weeks and small, sustained reductions in frequency. 📉
But no lasting impact on distress or broader outcomes. And almost 1 in 3 participants in the VR arm were admitted to hospital during treatment. ⚠️
But no lasting impact on distress or broader outcomes. And almost 1 in 3 participants in the VR arm were admitted to hospital during treatment. ⚠️
November 26, 2025 at 7:41 AM
The trial found small reductions in voice severity at 12 weeks and small, sustained reductions in frequency. 📉
But no lasting impact on distress or broader outcomes. And almost 1 in 3 participants in the VR arm were admitted to hospital during treatment. ⚠️
But no lasting impact on distress or broader outcomes. And almost 1 in 3 participants in the VR arm were admitted to hospital during treatment. ⚠️
Reposted by Phil Corlett
Cognition Disconnected: The Influence of Domain-General Cognition (g) in Lesion-Deficit Mapping https://www.biorxiv.org/content/10.1101/2025.11.25.690275v1
November 26, 2025 at 8:15 AM
Cognition Disconnected: The Influence of Domain-General Cognition (g) in Lesion-Deficit Mapping https://www.biorxiv.org/content/10.1101/2025.11.25.690275v1
Reposted by Phil Corlett
Understanding cortical computation through the lens of joint-embedding predictive architectures https://www.biorxiv.org/content/10.1101/2025.11.25.690220v1
November 26, 2025 at 8:15 AM
Understanding cortical computation through the lens of joint-embedding predictive architectures https://www.biorxiv.org/content/10.1101/2025.11.25.690220v1
Reposted by Phil Corlett
Brenda Milner showed the world that memory isn’t one thing — the hippocampus supports our life stories, while other circuits let us keep learning skills.
Her research on patient H.M. built the foundation of cognitive neuroscience.
#WomenInScience #MemoryResearch #NeuroHistory
Her research on patient H.M. built the foundation of cognitive neuroscience.
#WomenInScience #MemoryResearch #NeuroHistory
November 25, 2025 at 10:05 PM
Brenda Milner showed the world that memory isn’t one thing — the hippocampus supports our life stories, while other circuits let us keep learning skills.
Her research on patient H.M. built the foundation of cognitive neuroscience.
#WomenInScience #MemoryResearch #NeuroHistory
Her research on patient H.M. built the foundation of cognitive neuroscience.
#WomenInScience #MemoryResearch #NeuroHistory
Reposted by Phil Corlett
The Synthetic Nomological Net: A search engine to identify conceptual overlap in measures in the behavioral sciences: https://osf.io/nfgmv
November 25, 2025 at 2:44 PM
The Synthetic Nomological Net: A search engine to identify conceptual overlap in measures in the behavioral sciences: https://osf.io/nfgmv
This is really great work. Perception of the Ebbinghaus Illusion INCREASES under psilocybin, due to changes in divisive normalization. Seems to challenge REBUS - since the belief that underwrites the illusion is stronger, not relaxed?
Our new paper is out in Nature Communications! nature.com/articles/s41...
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
November 24, 2025 at 2:59 PM
This is really great work. Perception of the Ebbinghaus Illusion INCREASES under psilocybin, due to changes in divisive normalization. Seems to challenge REBUS - since the belief that underwrites the illusion is stronger, not relaxed?
Reposted by Phil Corlett
Our new paper is out in Nature Communications! nature.com/articles/s41...
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
November 23, 2025 at 10:26 PM
Our new paper is out in Nature Communications! nature.com/articles/s41...
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
We combined psychophysics, 7T fMRI, and computational modeling of vision with placebo, 5mg, and 10mg psilocybin, in the same group of participants, to clarify the computational mechanisms of psychedelics. 🧵
Reposted by Phil Corlett
First, we looked at visual perception using the Ebbinghaus illusion, a classic example of how context shapes what we perceive. The contextual surround illusion got systematically stronger! It's not just a figure of speech: we literally see the world differently with psilocybin👁️
November 23, 2025 at 10:26 PM
First, we looked at visual perception using the Ebbinghaus illusion, a classic example of how context shapes what we perceive. The contextual surround illusion got systematically stronger! It's not just a figure of speech: we literally see the world differently with psilocybin👁️
Reposted by Phil Corlett
The Thing (1982) is a Thanksgiving movie.
Thought of it while prepping a Friendsgiving turkey today.
Thought of it while prepping a Friendsgiving turkey today.
November 22, 2025 at 6:33 PM
The Thing (1982) is a Thanksgiving movie.
Thought of it while prepping a Friendsgiving turkey today.
Thought of it while prepping a Friendsgiving turkey today.
Reposted by Phil Corlett
How do they know it’s because Batman is unexpected and not because he’s seen as a moral authority (albeit fictional)? What happens if you send in the Riddler? 🧪
The Batman Effect, just published in NATURE:
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
Unexpected events and prosocial behavior: the Batman effect - npj Mental Health Research
npj Mental Health Research - Unexpected events and prosocial behavior: the Batman effect
www.nature.com
November 22, 2025 at 1:17 PM
How do they know it’s because Batman is unexpected and not because he’s seen as a moral authority (albeit fictional)? What happens if you send in the Riddler? 🧪
Reposted by Phil Corlett
The Batman Effect, just published in NATURE:
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
Unexpected events and prosocial behavior: the Batman effect - npj Mental Health Research
npj Mental Health Research - Unexpected events and prosocial behavior: the Batman effect
www.nature.com
November 22, 2025 at 12:37 PM
The Batman Effect, just published in NATURE:
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
When an experimenter dressed as Batman boarded a train, passengers were significantly more likely to offer their seats to another “pregnant” experimenter than if Batman wasn’t present (67.21% vs. 37.66%) #SciComm 1/2
www.nature.com/articles/s44...
Reposted by Phil Corlett
This made me giggle
November 22, 2025 at 10:14 AM
This made me giggle
Reposted by Phil Corlett
Poetry Comics Month, Day 22
November 22, 2025 at 1:00 PM
Poetry Comics Month, Day 22
Reposted by Phil Corlett
“There’s a popular view that connectivity, in the Facebook sense, is a good thing. In my world, it’s really bad. Dense connectivity is the killer. It is death.” — Karl Friston. hbarjournal.substack.com/p/karl-frist...
Karl Friston — Functioning Brains and Psychotic Societies
On the Free Energy Principle, societal boundaries, cancer, and the beauty of sparsity.
hbarjournal.substack.com
November 21, 2025 at 6:13 PM
“There’s a popular view that connectivity, in the Facebook sense, is a good thing. In my world, it’s really bad. Dense connectivity is the killer. It is death.” — Karl Friston. hbarjournal.substack.com/p/karl-frist...
Reposted by Phil Corlett
Congratulations to Harriet De Wit, Ph.D., for being awarded the Barbara Fish Memorial Award! ☺️ #ACNP2026
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
November 21, 2025 at 7:10 PM
Congratulations to Harriet De Wit, Ph.D., for being awarded the Barbara Fish Memorial Award! ☺️ #ACNP2026
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
Reposted by Phil Corlett
📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 -
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
November 21, 2025 at 7:27 PM
📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 -
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
Reposted by Phil Corlett
Getting journal rejections like
November 21, 2025 at 5:50 PM
Getting journal rejections like
Reposted by Phil Corlett
Very cool new work from the Iglesias group at MGH: A probabilistic histological atlas of the human brain for MRI segmentation (also available at OpenNeuro - openneuro.org/datasets/ds0...) : www.nature.com/articles/s41...
A probabilistic histological atlas of the human brain for MRI segmentation - Nature
NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...
www.nature.com
November 21, 2025 at 3:32 PM
Very cool new work from the Iglesias group at MGH: A probabilistic histological atlas of the human brain for MRI segmentation (also available at OpenNeuro - openneuro.org/datasets/ds0...) : www.nature.com/articles/s41...
Reposted by Phil Corlett
also, never abbreviate "assistant professor' as "ass prof"
Science PSA: Never abbreviate “analysis” as “anal”. Ever.
November 21, 2025 at 11:00 AM
also, never abbreviate "assistant professor' as "ass prof"
Reposted by Phil Corlett
What happens if you hook up an energy-efficiency optimising RNN on active vision input?
It learns predictive remapping and path integration into allocentric scene coordinates.
Now out in patterns: www.cell.com/patterns/ful...
It learns predictive remapping and path integration into allocentric scene coordinates.
Now out in patterns: www.cell.com/patterns/ful...
November 21, 2025 at 8:01 AM
What happens if you hook up an energy-efficiency optimising RNN on active vision input?
It learns predictive remapping and path integration into allocentric scene coordinates.
Now out in patterns: www.cell.com/patterns/ful...
It learns predictive remapping and path integration into allocentric scene coordinates.
Now out in patterns: www.cell.com/patterns/ful...
Reposted by Phil Corlett
New preprint with super @manuelbaltieri.bsky.social !
Mathematical approaches to the study of agents
osf.io/preprints/ps...
Mathematical approaches to the study of agents
osf.io/preprints/ps...
OSF
osf.io
November 21, 2025 at 12:44 PM
New preprint with super @manuelbaltieri.bsky.social !
Mathematical approaches to the study of agents
osf.io/preprints/ps...
Mathematical approaches to the study of agents
osf.io/preprints/ps...
Reposted by Phil Corlett
Parietal cortex output neurons form a specialized population code that enhances the propagation of information to a downstream target and potentially improves the accuracy of decision-making
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Specialized structure of neural population codes in parietal cortex outputs - Nature Neuroscience
Cortical neurons comprising an output pathway form a specialized population code that enhances the propagation of information to a downstream target, potentially improving the accuracy of decision-mak...
www.nature.com
November 20, 2025 at 10:22 PM
Parietal cortex output neurons form a specialized population code that enhances the propagation of information to a downstream target and potentially improves the accuracy of decision-making
www.nature.com/articles/s41...
www.nature.com/articles/s41...