Lightnews — Scholar-powered news

David Katz @katzlab.bsky.social · 18h

Really looking forward to visiting Rutgers and @barrlab.bsky.social tomorrow!

Maureen Barr @barrlab.bsky.social · 19h

Rutgers peeps: David Katz is presenting this exciting work tomorrow Oct 8 at 2pm in Waksman 1001. #celegans

David Katz @katzlab.bsky.social · 1d

Very excited to share our very exciting story on how misinherited chromatin affects individual cells to cause a behavior defect in C. elegans (a thread👇) www.pnas.org/doi/10.1073/...

2 5

David Katz @katzlab.bsky.social · 1d

If the same thing is true in the corresponding human patients, might it be possible to revert cognitive/behavior deficits in the human patients also?

a colorful background with the words stay tuned written on it

ALT: a colorful background with the words stay tuned written on it

media.tenor.com

1 1

David Katz @katzlab.bsky.social · 1d

So, expressing germline genes in neurons can block their function in a way that is reversible if you shut off the inappropriate transcription

the man is wearing a suit and tie and clapping his hands .

ALT: the man is wearing a suit and tie and clapping his hands .

media.tenor.com

1 1 2

David Katz @katzlab.bsky.social · 1d

Turning off the ectopic germline gene expression in the neurons of worms that already have a chemotaxis behavior defect, reverses the behavior back to normal

a man in a tuxedo and top hat is pointing a gun with the hashtag trendizisst below him

ALT: a man in a tuxedo and top hat is pointing a gun with the hashtag trendizisst below him

media.tenor.com

1 1 3

David Katz @katzlab.bsky.social · 1d

So, could the chemotaxis behavior defect be due to an ongoing defect in an intact nervous system? If so, might it be possible to reverse the chemotaxis behavior defect even after the nervous system has fully formed?

1 1

David Katz @katzlab.bsky.social · 1d

And an intact nervous system

1 1

David Katz @katzlab.bsky.social · 1d

No changes in the embryonic lineage

1 1

David Katz @katzlab.bsky.social · 1d

Progeny of spr-5 (lsd1) and met-2 (setdb1) double mutants have germline genes expressed in somatic cells, which causes a severe chemotaxis behavior defect, but surprise...

a picture of a minion with the words whaaat written on it

ALT: a picture of a minion with the words whaaat written on it

media.tenor.com

1 1

David Katz @katzlab.bsky.social · 1d

The invariant C. elegans lineage and adult nervous system provide the perfect opportunity to find out how every cell responds to inappropriately inherited chromatin and altered transcription

1 3

David Katz @katzlab.bsky.social · 1d

Ever wonder how something as broad as a chromatin mutant causes cell specific phenotypes?

a black and white photo of the milky way galaxy with the words `` you are here '' written on it .

ALT: a black and white photo of the milky way galaxy with the words `` you are here '' written on it .

media.tenor.com

1 1

David Katz @katzlab.bsky.social · 1d

Very excited to share our very exciting story on how misinherited chromatin affects individual cells to cause a behavior defect in C. elegans (a thread👇) www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

5 10 41

David Katz @katzlab.bsky.social · 5d

So proud of my graduate student Monica Reeves for winning program student of the year in the Genetics and Molecular Biology program at Emory University @emory-gmb.bsky.social

9

David Katz @katzlab.bsky.social · 26d

Really cool. Looking forward to reading it. The Peters’ lab publishes amazing science.

2

David Katz @katzlab.bsky.social · 29d

A lot of important views expressed here. I am just curious how the potential to flood the zone with fake papers feeds into all of this?

1

Reposted by David Katz

Oded Rechavi @odedrechavi.bsky.social · Aug 16

C. elegans initiating a small RNA response

1 3 28

David Katz @katzlab.bsky.social · Aug 11

Very excited to be back at the Epigenetics GRC, this time in Barcelona! #epigeneticsgrc2025

1 19

David Katz @katzlab.bsky.social · Aug 4

Stand up for science. Stand up as if our lives and our economy depend on it. Because, actually, they do. #standupforscience

Colette Delawalla @cdelawalla.bsky.social · Aug 4

Congress says they have our back...let's hold them to their word!

All gas, no breaks this August with the 31 Days of Action campaign.

Sign up for our daily action notes here: act.standupforscience.net/forms/31-day...

1 11 25

David Katz @katzlab.bsky.social · Aug 4

Quiet. Don’t tell anyone.

1

David Katz @katzlab.bsky.social · Jul 31

Thank you. I will put my head down and continue to do the best science that I can.

1 1

David Katz @katzlab.bsky.social · Jul 31

Harmit please tell us that it is all going to be alright.

1 1

David Katz @katzlab.bsky.social · Jul 30

Something seems to be wrong with the action network link, but the YouTube link for the lecture seems to be fine

David Katz @katzlab.bsky.social · Jul 29

Excited to be sharing the science from my lab on epigenetic inheritance and Alzheimer’s disease with the community. If you want to watch, here is the link www.youtube.com/live/O4AsL8m...
@standupforscience.bsky.social @sci4ga.bsky.social #StandUpForScience actionnetwork.org/events/teach...

actionnetwork.org

1 6 31

David Katz @katzlab.bsky.social · Jul 25

Looking forward to engaging with the community and telling people about our science.

Quinn Eastman @qeastman.bsky.social · Jul 24

#Epigenetics is a stretchy term -- looking forward to hearing @katzlab.bsky.social explain it next week (and connection to #Alzheimers) at Wild Heaven Toco Hills -- with @standupforscience.bsky.social @sci4ga.bsky.social #StandUpForScience actionnetwork.org/events/teach...

3 8

David Katz @katzlab.bsky.social · Jul 8

Great idea.

Dr. Lucky Tran @luckytran.com · Jul 8

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

3

David Katz @katzlab.bsky.social · Jul 8

Excited to be talking to the community about our work and about why funding science is so important. Come join us! @standupforscience.bsky.social @sci4ga.bsky.social

Quinn Eastman @qeastman.bsky.social · Jul 7

Looking forward to hearing @katzlab.bsky.social explain #epigenetics and connection between histone methylation and neurodegeneration -- part of our Teach In series w/ @standupforscience.bsky.social @sci4ga.bsky.social

1 1 7