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Ranit Kedmi

@kedmiranit.bsky.social

750 followers 150 following 48 posts

#newPI at @WeizmannScience | study immunity through the lens of antigen presentation | Dan Littman alum https://www.kedmilabweizmann.com

www.kedmilabweizmann.com

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Ranit Kedmi @kedmiranit.bsky.social · May 27

Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabucsf.bsky.social and @chrysothemisbrown.bsky.social , and our own (now in @nature.com, www.nature.com/articles/s41...), reports that the dietary pTreg program is initiated by RORγt⁺ APCs. /1

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Ranit Kedmi @kedmiranit.bsky.social · 2d

Simply wonderful!

Science News @scinews.bsky.social · 2d

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Reposted by Ranit Kedmi

Tcellogic (Sue Kaech) @tcellogic.bsky.social · 16d

“If you look back at the data, 250 years ago, 40% of kids never made it to adulthood. Today, it’s 4%. The majority of that decrease is due to vaccines. Vaccines have saved more lives than any other type of medical intervention, including antibiotics... -Dr. Drew Weissman, Nobel Laureate.

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Ranit Kedmi @kedmiranit.bsky.social · 18d

Simply wonderful!

Adrian Liston @labliston.bsky.social · 19d

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

currentprotocols.onlinelibrary.wiley.com

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Ranit Kedmi @kedmiranit.bsky.social · 24d

x.com/shouval/stat...

Ruth Shouval on X: "For the full text of the statement in English and Hebrew: https://t.co/bwk7HLRN49" / X

For the full text of the statement in English and Hebrew: https://t.co/bwk7HLRN49

x.com

Reposted by Ranit Kedmi

Joanna Groom @groomlab.bsky.social · 26d

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com
www.nature.com/articles/s41...

This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social

Thread below...

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity - Nature Immunology

Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...

www.nature.com

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Ranit Kedmi @kedmiranit.bsky.social · Aug 27

And she will also present a poster tomorrow afternoon. Go say hi! #EMBObarrierTissues

Ranit Kedmi @kedmiranit.bsky.social · Aug 27

I wish I could be there!
Our amazing @annarudnitsky.bsky.social will give a talk on Friday — don’t miss it!
www.nature.com/articles/s41...

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Ranit Kedmi @kedmiranit.bsky.social · Aug 23

The #IUIS2025 was way above my expectations! It was so great to meet old and new friends and to share our work. @iuis-online.bsky.social

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Ranit Kedmi @kedmiranit.bsky.social · Aug 23

Was great to meet you in person Brenda. Keep up the great work.

Ranit Kedmi @kedmiranit.bsky.social · Aug 20

It was mind blowing

Caetano Reis e Sousa @reisesousalab.bsky.social · Aug 20

Great keynote lecture by Ruslan Medzhitov on how the “educated” immune system of pet shop mice allows them to resist experimental allergic sensitisation. Thought provoking, as usual. #IUIS2025.

Reposted by Ranit Kedmi

Caetano Reis e Sousa @reisesousalab.bsky.social · Aug 20

Great keynote lecture by Ruslan Medzhitov on how the “educated” immune system of pet shop mice allows them to resist experimental allergic sensitisation. Thought provoking, as usual. #IUIS2025.

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Reposted by Ranit Kedmi

International Union of Immunological Societies @iuis-online.bsky.social · Aug 20

Some pics from the #RisingStars Day 2!

Don't forget to share — which sessions have you liked the most so far?

#ImmunologyWithoutBorders

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Reposted by Ranit Kedmi

International Union of Immunological Societies @iuis-online.bsky.social · Jul 28

Meet Dr @KedmiRanit, PI at Weizmann Institute. Her research reveals how immune cells coordinate to shape T cell responses. At #IUIS2025, she’ll present “A coordinated cellular network regulates intestinal tolerance.” 🔬🌍 https://loom.ly/CwagY2g #RisingStars2025 #RoadtoVienna

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Ranit Kedmi @kedmiranit.bsky.social · Jul 14

Very cool!

Reposted by Ranit Kedmi

Nature @nature.com · Jul 3

Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity, says Alon Chen

https://go.nature.com/40wXMx6

How we’re rebuilding the Weizmann Institute — and our hopes for a better future

Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity.

go.nature.com

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Ranit Kedmi @kedmiranit.bsky.social · Jun 28

Thanks for choosing me!
See you there 🌟

International Union of Immunological Societies @iuis-online.bsky.social · Jun 18

IUIS and its Early Career Committee are thrilled to announce the IUIS #RisingStars2025 Cohort! 🌟
https://loom.ly/f5Gq1f8
Fifteen exceptional early-career scientists from across the globe to join our #RisingStars Program
Don’t miss your chance to meet them https://loom.ly/CwagY2g

Ranit Kedmi @kedmiranit.bsky.social · Jun 9

Thank you

Ranit Kedmi @kedmiranit.bsky.social · Jun 2

Thanks Natalia! I would say so.

Ranit Kedmi @kedmiranit.bsky.social · May 30

Thank you.

Ranit Kedmi @kedmiranit.bsky.social · May 29

Free/public access: rdcu.be/enZTa

Reposted by Ranit Kedmi

Thiago Carvalho @cyrilpedia.bsky.social · May 28

'However, we now report that food-specific pTreg cells are exclusively induced by the recently identified RORγt APCs4–8 and not by cDCs. Instead, our data suggest that pTreg–cDC1 interactions in steady-state limit the expansion of food-specific CD8αβ T cells.'
www.nature.com/articles/s41...

A coordinated cellular network regulates tolerance to food - Nature

Nature - A coordinated cellular network regulates tolerance to food

www.nature.com

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Ranit Kedmi @kedmiranit.bsky.social · May 28

Thank you.

Ranit Kedmi @kedmiranit.bsky.social · May 27

As this story is the first story to come out from my lab, I want to specially thank ‪@eranelinav.bsky.social‬ and the entire Systems Immunology Department for putting their trust in me. /17

Ranit Kedmi @kedmiranit.bsky.social · May 27

A huge shoutout to the incredible Anna Rudnitsky that led this project as a master student at the @weizmanninstitute.bsky.social. Many thanks to other lab members that contribute to this work, and to our collaborators and next-door neighbors @zivshulman.bsky.social /16

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Ranit Kedmi @kedmiranit.bsky.social · May 27

We concluded that:

🚩 APCs are specialized, dedicated populations

🚩 Tolerance is built through an antigen-specific cellular network

🚩 Dietary immune responses can mount acute effector reactions when needed—within a broader strategy of tolerance
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