Kevin Staras
@kevinstaras.bsky.social
280 followers 220 following 24 posts
NeuroProf at University of Sussex, UK • Synapses, Circuits, Plasticity, Disease, Decision-making https://www.thestaraslab.org/
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Reposted by Kevin Staras
pjsjostrom.bsky.social
🧪 We recently published our first micro-publication! This paper highlights the pitfalls of using extracellular stimulation to recruit synapses in neocortical circuits, as it lacks specificity. www.micropublication.org/journals/bio...
Reposted by Kevin Staras
carandinilab.net
I'd like to make a list of PhD programs that (1) are in Europe (which does include the UK); (2) offer opportunities in systems neuroscience; and obviously (3) pay a stipend. Please share and/or respond to add your suggestions?
Reposted by Kevin Staras
megancarey.bsky.social
We are super excited about this news!!! 🤩 #ERCAdG
Reposted by Kevin Staras
megancarey.bsky.social
Oops the original post was deleted! The news is here: bsky.app/profile/cham...
champalimaudr.bsky.social
👏 Congratulations to @megancarey.bsky.social, principal investigator at @champalimaudr.bsky.social on winning a 2.5M€ #AdvancedGrantInLifeSciences, awarded by the @erc.europa.eu, to develop the project 🧠 SCUPTABELLUM - Sculpting cerebellar activity across timescales.
Reposted by Kevin Staras
neuroluci.bsky.social
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇

bit.ly/44aVm9E
Reposted by Kevin Staras
mmaravall.bsky.social
Posting this after some recent conversations with potential international applicants - still time to apply to our Masters courses and International PhD Academy for 2025 entry - join the diverse and vibrant Neuroscience community on our beautiful campus next to Brighton
sussexneuro.bsky.social
Want to join our vibrant postgrad community?

Discover all our Neuroscience courses here: www.sussex.ac.uk/study/subjects/neuroscience

Including:
🏫 International PhD Academy
🏫 Masters courses
🏫 Opportunities across several schools: Life Science; Psychology; Computer Science & AI; and BSMS
Neuroscience : University of Sussex
Discover our undergraduate courses, Masters and PhD degrees in neuroscience.
www.sussex.ac.uk
Reposted by Kevin Staras
adrianawanner.bsky.social
I am very happy and thankful for having been part of this amazing journey. Enjoy exploring this incredibly rich dataset!
alleninstitute.org
How does the brain work?

Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵

🧠📈
Reposted by Kevin Staras
kevinstaras.bsky.social
Aw, we got the cover for our new paper on X-ray imaging and atlas building in the snail brain. www.pnas.org/doi/10.1073/... Thanks @pnas.org .. and to @sussexneuro.bsky.social @leverhulme.bsky.social @ukri.org for funding support #invertebrate #brain #neuroscience THREAD: bsky.app/profile/kevi...
kevinstaras.bsky.social
Michael Crossley led the experimental work, supported by Anna Simon, @arndroth.bsky.social and
@enzomarra.bsky.social Thanks to @sussexneuro.bsky.social @leverhulme.bsky.social @ukri.org and @diamondlightsource.bsky.social for funding support. Thanks for reading! 10/10
kevinstaras.bsky.social
Our approach should readily generalize to other model systems with comparable brain sizes (e.g. other molluscs, crustacea, annelids, insects). On its own, it won’t yield a full wiring diagram, but it does rapidly provide a detailed overview map for atlas building and comparative studies. 9/10
kevinstaras.bsky.social
This provides the locations of principal feeding-circuit cell types, including motoneurons, CPG neurons and modulatory cells, alongside a detailed summary of their main functional properties. 8/10
kevinstaras.bsky.social
We also brought together the anatomical mapping and functional information to establish the beginnings of a fully scalable functional cell atlas of the brain of Lymnaea stagnalis: sites.google.com/view/snailbr... 7/10
kevinstaras.bsky.social
The consistent positioning of neurons across Lymnaea brains means the atlas can guide follow-up functional experiments. Targeting a non-superficial region led to the discovery of DINE (“Diamond Neuron”), an apt name 😜 because it activates the food ingestion circuitry. 6/10
kevinstaras.bsky.social
The 3D reconstruction revealed the organization of neurons beneath the surface layer for the first time. It turns out around half the neurons (coloured orange) are non-superficial - a hidden world of circuit components that can now be studied. 5/10
kevinstaras.bsky.social
We then used the excellent volume image-sharing, annotation, and reconstruction platform
@webknossos.org to fully reconstruct the buccal ganglia (one side is shown here) housing the main feeding circuitry, yielding the first accurate estimate of the total number of neurons: ~1100. 4/10
kevinstaras.bsky.social
Michael Crossley led the experimental work, supported by Anna Simon, @arndroth.bsky.social and @enzomarra.bsky.social Thanks to @sussexneuro.bsky.social @leverhulme.bsky.social @ukri.org and @diamondlightsource.bsky.social for funding support. Thanks for reading! 10/10
kevinstaras.bsky.social
Our approach should readily generalize to other model systems with comparable brain sizes (e.g. other molluscs, crustacea, annelids, insects). On its own, it won’t yield a full wiring diagram, but it does rapidly provide a detailed overview map for atlas building and comparative studies. 9/10
kevinstaras.bsky.social
This provides the locations of principal feeding-circuit cell types, including motoneurons, CPG neurons and modulatory cells, alongside a detailed summary of their main functional properties. 8/10
Sample image showing detailed information on different neuron types in the Lymnaea brain.
kevinstaras.bsky.social
We also brought together the anatomical mapping and functional information to establish the beginnings of a fully scalable functional cell atlas of the brain of Lymnaea stagnalis: sites.google.com/view/snailbr... 7/10
kevinstaras.bsky.social
The consistent positioning of neurons across Lymnaea brains means the atlas can guide follow-up functional experiments. Targeting a non-superficial region led to the discovery of DINE (“Diamond Neuron”), an apt name 😜 because it activates the food ingestion circuitry. 6/10
Figure shows a cross section view of the ganglia with an orange neuron, DINE, highlighted. It also shows electrophysiological traces with DINE driving a robust fictive feeding rhythm.