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kuba sędziński

@kuba-sedzinski.bsky.social

420 followers 630 following 37 posts

Studies how to build tissues. Cell developmental biology and biophysics of mucociliary epithelia. Group leader at reNEW, University of Copenhagen. https://renew.ku.dk/research/sedzinski_group/

renew.ku.dk

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Reposted by kuba sędziński

Seema Grewal @seemagrewal.bsky.social · 1d

So sad to hear the news - John truly was an inspiration to so many, and one of a kind.

www.cam.ac.uk/research/new...

Nobel Laureate Professor Sir John Gurdon dies aged 92

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.

www.cam.ac.uk

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Reposted by kuba sędziński

paveltomancak.bsky.social @paveltomancak.bsky.social · 1d

Jonathan's "Opus Magnum" is finally out. Fundamental discovery. Congratulations!

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 1d

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

Cracking organisms’ energy code

Researchers define rules governing how growing microorganisms use energy efficiently

www.mpi-cbg.de

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kuba sędziński @kuba-sedzinski.bsky.social · 4d

Lots of Polish letters😊

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kuba sędziński @kuba-sedzinski.bsky.social · 5d

Fantastic overview!

Barriga Lab @eliasbarrigalab.bsky.social · 6d

New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration

In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.

www.annualreviews.org/content/jour...

Bioelectricity in Morphogenesis

Bioelectricity is likely as old as life itself. From the moment the first proto-cell was enclosed in a lipid bilayer, a membrane potential arose. Thus, one can expect that bioelectrical activities inf...

www.annualreviews.org

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kuba sędziński @kuba-sedzinski.bsky.social · 11d

a man with a mustache is holding a piece of paper with the word science written on it .

ALT: a man with a mustache is holding a piece of paper with the word science written on it .

media.tenor.com

kuba sędziński @kuba-sedzinski.bsky.social · 12d

thank you🥰

kuba sędziński @kuba-sedzinski.bsky.social · 14d

Awesome! Please expect an email 😊

kuba sędziński @kuba-sedzinski.bsky.social · 14d

Thank you, Rikki! Curious if we could apply your model to determine pattern in this tissue😎. Here, there is lots of mixing of cells, especially in the very beginning. Looks like the pattern emerges fast, but it gets more defined with time! Would be great to try😊

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Reposted by kuba sędziński

Barriga Lab @eliasbarrigalab.bsky.social · 15d

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

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kuba sędziński @kuba-sedzinski.bsky.social · 15d

Thank you, Silvia! Much appreciated!

kuba sędziński @kuba-sedzinski.bsky.social · 15d

I hope so🤓

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Thanks, Vanessa! It looks so much better without the mp4 compression:) and when I manage to put it on a white background 🫠. Looking forward to your thoughts! Many thanks and hope to catch up soon 💪

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Thanks, Bianca! It would not be possible without your help!💪

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Thanks, Osvaldo! Looking forward to your feedback!

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Here, on a white background

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Here, on a white background

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Here, on a white background

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Here, on a white background

kuba sędziński @kuba-sedzinski.bsky.social · 16d

here, on a white background

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Thank you, Joaquin! I was dreaming about the 🔥Elmo🥰

kuba sędziński @kuba-sedzinski.bsky.social · 16d

Thanks, Marta! Still some room to improve🤓

kuba sędziński @kuba-sedzinski.bsky.social · 16d

14/14 Work was performed at @renewglobal.bsky.social. Many thanks to Mari Tolonen (main driver💪) Ziwei Xu, Varun Kapoor @kapoorlabs.bsky.social, and Bianca Dumitrascu @bimidu.bsky.social & Özgur Beker from @columbiauniversity.bsky.social . 🙏to all authors!👏

kuba sędziński @kuba-sedzinski.bsky.social · 16d

13/14 We're excited to make our experimental and computational pipeline open-source! Check it out and let us know your thoughts!
🔗 Code: github.com/kapoorlab/CopenhagenWorkflow & github.com/Sedzinski-Lab/trackomics/

GitHub - kapoorlab/CopenhagenWorkflow: Copenhagen Worklow

Copenhagen Worklow. Contribute to kapoorlab/CopenhagenWorkflow development by creating an account on GitHub.

github.com

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kuba sędziński @kuba-sedzinski.bsky.social · 16d

12/14 This is not a thoroughly solved problem, though! Technical hurdles (segmentation errors) and biological reality (overlapping but noisy phenotypes) remain challenges. The next frontier is integrating dynamic data with molecular profiles (from e.g., spatial transcriptomics).

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kuba sędziński @kuba-sedzinski.bsky.social · 16d

11/14 This morphodynamic approach offers a new layer of info. It could complement static snapshots from single-cell genomics (scRNA-seq) by providing a continuous, spatially-aware view of how cell states transition over time. Like the difference between a photo and a movie!

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