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Reposted

Nature Cell Biology @natcellbio.nature.com · 4d

💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology

Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

bit.ly

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paveltomancak.bsky.social @paveltomancak.bsky.social · 4h

We have lost a brilliant mind.

Max Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 9h

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend.

mpl.mpg.de/news/article...
@fau.de

📸 Stephan Spangenberg

Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).

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paveltomancak.bsky.social @paveltomancak.bsky.social · 4h

So sorry to hear this. Jochen was a brilliant scientist, facing enormous personal health challenges but you would never hear him complain or pity himself. A true hero of science. RIP

Reposted

Nicolas Chiaruttini @nkiaru.bsky.social · 1d

#QuPath + Imglib2 and #BDV ❤️

Promising start!

(Mainly Léo and Pete's work github.com/qupath/qupat... + a small addition)

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paveltomancak.bsky.social @paveltomancak.bsky.social · 1d

Jonathan's "Opus Magnum" is finally out. Fundamental discovery. Congratulations!

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 1d

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

Cracking organisms’ energy code

Researchers define rules governing how growing microorganisms use energy efficiently

www.mpi-cbg.de

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Reposted

Reto Fiolka @retof.bsky.social · 2d

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

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Reposted

Cian O'Donnell @cianodonnell.bsky.social · 2d

drosophila gene names never fail to crack me up

Screenshot from Neuroscience Bulletin journal webpage with text:

Sandman is a Sleep Switch in Drosophila

Research Highlight | Published: 13 September 2016
Volume 32, pages 503-504, (2016) Cite this article

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Reposted

Thibaut Brunet @thibautbrunet.bsky.social · 3d

Latest from ours: www.cell.com/cell-reports...

This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

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Maik Bischoff @maikbischoff.bsky.social · 5d

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls

Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨

🔗 www.nikonsmallworld.com/galleries/20...

#NikonSmallWorld #Microscopy #ScienceArt

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Reposted

Anders H. Lund @andershlund.bsky.social · 5d

We have an open group leader position in diabetes 1 research.
Please circulate!

www.nature.com/naturecareer....

164887 Professor or Associate Professor and Research Group Leader with special focus on molecular me - Copenhagen, Hovedstaden (DK) job with The Biotech Research and Innovation Centre (BRIC), Universi...

BRIC wishes to recruit a strongly motivated scientist at Associate Professor or Professor level for an independent research group leader position. ...

www.nature.com

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Reposted

TheLovelyLab @thelovelylab.bsky.social · 6d

good ole Louisville KY
@slewzeus.bsky.social @burgesslab.bsky.social @benoitbruneau.bsky.social @chrmosimann.bsky.social @lucksmith.bsky.social @docdellaire.bsky.social @fish4walking.bsky.social @daphsci.bsky.social @mads100tist.bsky.social

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Reposted

CEITEC @ceitec.eu · 7d

Yesterday, Radovan Fiala received the Silver Medal of Masaryk University for his outstanding contribution to NMR spectroscopy and structural biology 🔬 Congratulations! 👏
#CEITECScience
@masarykuniversity.bsky.social
📷 Martin Indruch

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Reposted

Joachim Goedhart @joachimgoedhart.bsky.social · 8d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Reposted

Heather Harrington @haharrington.bsky.social · 7d

Two years today! Very grateful 🙏 @mpi-cbg.de @csbdresden.bsky.social @math-mpicbg.bsky.social

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Reposted

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 8d

Schering Young Investigator Award 2025 by the Schering Stiftung for Agnes Toth-Petroczy @tothpetroczylab.bsky.social @mpi-cbg.de @csbdresden.bsky.social. She receives the award for her work on the evolution, diversity, and function of proteins. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...

New Perspectives on the Hidden World of Proteins

 Schering Young Investigator Award 2025 goes to Agnes Toth-Petroczy

www.mpi-cbg.de

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paveltomancak.bsky.social @paveltomancak.bsky.social · 9d

Some things never change. 30 years! #ISG

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paveltomancak.bsky.social @paveltomancak.bsky.social · 9d

Traveling in #Germany. The open hostility of a Sachsen lady at the Bahnhof store towards an immigrant customer who just wanted to buy cigarettes. He was on a job. How are they suppose to belong? Broken society. But then, super nice conversation with a Kosovo Albanian in a Heidelberg taxi. 🤷‍♂️

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Reposted

Gaowen Liu @gaowen.bsky.social · 10d

Sex or growth? Life must continually balance these strategies. We forced yeast to choose and captured the trade-off in real time. Evolution rewired existing regulators and fixed them through genetic assimilation, creating specialists for sex at the cost of growth.
www.biorxiv.org/cgi/content/...

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paveltomancak.bsky.social @paveltomancak.bsky.social · 11d

Fully agree, it is feedbacks all the way.

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Reposted

Akankshi Munjal @akankshi.bsky.social · 12d

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

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paveltomancak.bsky.social @paveltomancak.bsky.social · 11d

Looking for the inner fish?

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paveltomancak.bsky.social @paveltomancak.bsky.social · 11d

Do you mean to redirect it all to a centralized pre-print server, such as bioRxiv? Besides costing A LOT of money, this smells of a monopoly, which is never good.

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Reposted

Cells & Development @cellsdev.bsky.social · 12d

In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here:
doi.org/10.1016/j.cd...

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paveltomancak.bsky.social @paveltomancak.bsky.social · 12d

I cannot claim to understand the economics of it, but I think the hefty price tag on OA publication comes from having dedicated people perform these kinds of checks. (besides peer review and, well, profit). I don't see how bioRxiv can do anything near this and remain "free".

Reposted

Junior European Drosophila Investigators @fly-jedi.bsky.social · 12d

Dear JEDIs,
as we are self-organizing using the #EDRC as a nucleator we decided it is time for a JEDI database to boost our network! If you identify as a JEDI, please contact us here or send a mail to [email protected] to be added to our database.
#Drosophila
@fly-eds.bsky.social

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